Positions

Assistant Professor
Department of Pediatrics
Section of Gastroenterology, Hepatology & Nutrition
Baylor College of Medicine and Texas Children's Hospital
Houston, Texas, United States

Education

Clinical Fellowship at Baylor College of Medicine & Texas Children's Hospital
Pediatric Gastroenterology, Hepatology & Nutrition
Residency at Baylor College of Medicine & Texas Children's Hospital
Pediatrics
Internship at Baylor College of Medicine & Texas Children's Hospital
Pediatrics
MD from Baylor College Of Medicine
PhD from Baylor College of Medicine
Translational Biology and Molecular Medicine
AB from Harvard University
Physics, cum laude

Certifications

Medical License
Texas Medical Board
Board Certification - General Pediatrics
American Board of Pediatrics

Professional Interests

  • Neonatal Gastroenterology, Hepatology & Nutrition
  • Sex Differences in Nutritional Physiology
  • Gut Microbiome and Probiotics
  • Neurogastroenterology and Motility
  • Liver and Intestinal Physiology
  • Undernutrition
  • Bile Acids
  • Metabolomics and Biomarkers
  • Nuclear Hormone Receptors
  • Tropical Medicine

Professional Statement

Our goal is to define mechanisms through which early life undernutrition alters metabolism and to determine how undernutrition influences intestinal and liver function. Undernutrition causes acute medical problems, but also long term health problems that may result from permanent epigenetic changes that alter transcription or via changes in the gut microbiome. Current studies focus on how malnutrition alters hepatic secretion, transcriptional programming, gastrointestinal motility, and host-microbiome interactions to impact growth. Our work is pertinent to those suffering from nutritional deficiencies caused by a wide range of medical and socioeconomic factors, including preterm and underweight newborns in the neonatal intensive care unit, adolescents with anorexia nervosa, and children with severe acute malnutrition in the developing world.

Selected Publications

Funding

K08 Mentored Clinical Scientist Research Career Development Award - #1 K08 DK113114-01
Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
Nuclear Receptor Mediated Bile Acid Alterations and Coagulopathy in Protein-Energy Undernutrition
AGA-Rome Foundation Functional GI and Motility Disorders Pilot Award
Grant funding from American Gastroenterological Association / Rome Foundation
Bile Acid Mediated Dysmotility in Protein-Energy
Undernutrition
Chao Physician-Scientist Award
Grant funding from Ting Tsung and Wei Fong Chao Foundation
Nuclear Receptor Mediated Bile Acid Alterations and Coagulopathy in Protein-Energy Undernutrition
ANMS Research Grant
Grant funding from American Neurogastroenterology and Motility Society
Bile Acids and Intestinal Dysmotility in Early-Life Undernutrition
Functional and Mechanistic Award
Grant funding from The Alkek Center for Metagenomics and Microbiome Research
Microbial Mechanisms of Pathogenesis Underlying non-Helicobacter Gastritis
Pilot/Feasibility Award
Grant funding from The Texas Medical Center Digestive Disease Center
Persistent Epigenetic and Metabolic Consequences of Early Undernutrition.
NASPGHAN Foundation / Nestle Nutrition Research Young Investigator Development Award
Grant funding from North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Glycan metabolism shapes the undernourished intestinal microbiome and influences weight gain
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) - #5T32DK007664
Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
Mechanisms of Dysregulation of Bile Acid Synthesis in Protein-Energy Undernutrition
Early Career Award
Grant funding from Thrasher Research Fund
The Intestinal Microbiome as a Biomarker and Therapeutic Target in Severe Acute Malnutrition
Young Investigator Grant for Probiotics Research
Grant funding from Global Probiotics Council
Elucidating the Role of the Intestinal Microbiome in Protein-Energy Undernutrition
Ruth L. Kirschstein National Research Service Award for Individual Predoctoral M.D./Ph.D. Fellows (F30) - #5F30DK081269
Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
Mechanisms of Immunomodulation by Probiotic L. reuteri in Acute Gastroenteritis