Positions

Director
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States
Professor
Department of Medicine
Baylor College of Medicine
Houston, Texas, United States
Dudley and Tina Sharp Chair for Cancer Research
Baylor College of Medicine
Houston, Texas, United States

Education

Advanced Training from National Cancer Institute
Medical Oncology
Residency from Johns Hopkins Hospital
Internal Medicine
M.D. from University of Missouri Medical School
Medicine
A.B. from University Of Missouri
Zoology
Fellowship at National Cancer Institute
Medical Oncology
Residency at Johns Hopkins University Hospital
Internal Medicine
MD from University of Missouri - Columbia School of Medicine

Certifications

American Board of Internal Medicine
American Board of Internal Medicine, Medical Oncology
Medical Oncology
American Board of Internal Medicine

Professional Interests

  • Diagnosis and treatment of breast cancer
  • Biology of breast cancer
  • Resistance to ER and HER2-targeted therapies in breast cancer
  • Breast Disease and Cancer

Selected Publications

Funding

Cancer Center Support Grant
- #P30 CA125123-06
Grant funding from NIH
The mission of the DLDCC is to further reduce suffering and mortality from cancer through its research, education, patient care, and outreach activities. Our Center is a matrix cancer center with research members from nearly all College departments and academic units who have a commitment to cancer research and/or patient care. The DLDCC exists to facilitate the research of its members, to bring together researchers from different departments and centers for collaborative, multidisciplinary approaches to cancer, and to provide infrastructure support for the conduct of cancer research.
MUSC/Baylor Breast Cancer Research Initiative for Developing Growth & Education (BRIDGE) Program
- #BC103072
Grant funding from CDMRP through MUSC
The overall goal of this proposal is to mentor the MUSC in developing a Breast Cancer Research Program.
Komen Promise Grant
- #PG 221410
Grant funding from Komen Foundation
Restoring hormone sensitivity of late recurrences in breast cancer patients. The overall goal of this proposal is to use novel preclinical models developed for these studies and equally unique patient samples, to develop novel drug strategies to target the SRCs themselves and upstream kinases.
Development of Coactivator-Dependent, First-in-class Therapies for Breast Cancer
- #BC120894
Grant funding from DOD
The major goal of this grant is to identify accurate predictors and novel therapeutic drug approaches to prevent and overcome the development of late recurrence and hormone-resistant metastases of BCs
SPORE - Translational Research in Breast Cancer
Grant funding from NIH/NCI
The major goal of this large Specialized Program of Resource Excellence is to expedite the translation of basic research into applied clinical applications in breast cancer detection, treatment, and prevention. There are 4 Projects and 4 Cores Resources including a Pathology Resource and Tissue Resource.