Akash J. Patel, M.D.

Ruth Mitzner Professor in Neurosurgery

(713) 798-4696

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Email

akash.patel@bcm.edu

Positions

Ruth Mitzner Professor in Neurosurgery: Neurosurgery
Baylor College of Medicine
Houston, TX, US

Member: Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Professor (Joint Appointment): Department of Otolaryngology – Head & Neck Surgery
Baylor College of Medicine
Houston, Texas, United States

Residency Program Director: Neurosurgery
Baylor College of Medicine
Houston, Texas, United States

Director of Brain Tumor Surgery: Neurosurgery
Baylor College of Medicine
Houston, Texas, United States

Addresses

Baylor St. Luke's McNair Campus (Clinic): 7200 Cambridge
9th Floor
Houston, TX, 77030
United States
Phone: (713) 798-4696

Baylor St. Luke's McNair Campus (Office): 7200 Cambridge
9th Floor
Houston, TX, 77030
United States
Phone: (713) 798-4696

Education

BA from Rice University: Houston, Texas, United States; Biochemistry

MD from Baylor College of Medicine: Houston, Texas, United States

Residency at Baylor College of Medicine: Houston, Texas, United States

Certifications

Diplomate: American Board of Neurological Surgeons

Honors & Awards

Educator of the Year (2021): Congress of Neurological Surgeons

Christopher C. Getch Fellowship (2015): Congress of Neurological Surgeons

Leadership Fellow, CNS Leadership Institute (2017): Congress of Neurological Surgeons

Elected to the Society of Neurological Surgeons (2023): Society of Neurological Surgeons

Vanguard Leadership in Health Care, CNS Leadership Institute (2026): Congress of Neurological Surgeons

Elected to the American Academy of Neurological Surgery (2026): American Academy of Neurological Surgery

Professional Interests

Open and endoscopic surgery for malignant and benign brain tumors
Skull base tumors
Meningiomas, acoustic neuromas, glioblastomas
Brain tumor surgery in deep and eloquent brain regions
Surgery and genetics of meningiomas and schwannomas
Neurofibromatosis

Professional Statement

Dr. Patel is a board-certified neurosurgeon specializing in brain and skull base tumors, with particular expertise in meningiomas and vestibular schwannomas (acoustic neuromas). He provides individualized care through careful evaluation, advanced microsurgical techniques, and multidisciplinary collaboration. His NIH-funded laboratory studies the molecular biology of meningiomas to understand why they form, grow, and recur, with the goal of identifying new treatments.

Websites

Baylor College of Medicine Department of Neurosurgery

Akash Patel, MD | Brain Tumor & Skull Base Neurosurgery

Independent professional website of Dr. Patel, with clinical, research, and consultation information.

Google Scholar

Publications and citations on Google Scholar.

NCBI My Bibliography

Public bibliography of peer-reviewed publications.

Jan and Dan Duncan Neurologic Research Institute

Videos

Advancing Meningioma Research: Interview with the Texas Association of Neurological Surgeons (2026)

Dr. Patel discusses collaboration in neurosurgery and how his laboratory uses machine learning and AI to study meningioma biology and molecular classification.

Selected Publications

Bayley JC V, Hadley CC, Harmanci AO, Harmanci AS, Klisch TJ, Patel AJ. " Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies " Sci Adv. 2022 Feb 4; 8 (5)
Pubmed PMID: 35108039.
Jackson HN, Hadley CC, Khan AB, Gadot R, Bayley JC V, Shetty A, Mandel J, Jalali A, Gallagher KK, Sweeney AD, Harmanci AO, Harmanci AS, Klisch TJ, Gopinath SP, Rao G, Yoshor D, Patel AJ. " Racial and Socioeconomic Disparities in Patients With Meningioma: A Retrospective Cohort Study " Neurosurgery. 2022 Jan 1; 90 (1) : 114-123.
Pubmed PMID: 34982878.
Patel AJ, Wan YW, Al-Ouran R, Revelli JP, Cardenas MF, Oneissi M, Xi L, Jalali A, Magnotti JF, Muzny DM, Doddapaneni H, Sebastian S, Heck KA, Goodman JC, Gopinath SP, Liu Z, Rao G, Plon SE, Yoshor D, Wheeler DA, Zoghbi HY, Klisch TJ. " Molecular Profiling Predicts Meningioma Recurrence and Reveals Loss of DREAM Complex Repression in Aggressive Tumors " Proc Natl Acad Sci U S A. 2019 Oct 22; 116 (43) : 21715-21726.
Pubmed PMID: 31591222.
Patel AJ, Suki D, Hatiboglu M, Rao VY, Fox BD, Sawaya R. " Impact of Surgical Methodology on Functional Outcomes of Patients Undergoing Resection for Single Brain Metastasis " J Neurosurg. 2015 Mar 20; 1-12.
Pubmed PMID: 25794344.
Khan AB, English CW, Chen WC, Athukuri P, Bayley JC 5th, Brandt VL, Shetty A, Hadley CC, Choudhury A, Lu HC, Harmanci AO, Harmanci AS, Magill ST, Raleigh DR, Klisch TJ, Patel AJ. " Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma. " Acta Neuropathol. 2023 Apr ; 145 (4) : 501-503.
Pubmed PMID: 36729132.
Pugazenthi S, Patel B, English CW, Leidig WA, McGeehan KP, McCornack CR, Mok S, Anzaldua-Campos M, Nouri SH, Roberts K, Chatrath A, Khan A, Gadot R, Yano H, Klisch TJ, Harmanci AS, Patel AJ, Kim AH. " Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution. " Sci Adv. 2024 Oct 25; 10 (43) : eadn4419.
Pubmed PMID: 39441930.
Patel B, Pugazenthi S, English CW, Nitturi V, Pari SS, Mahlokozera T, Leidig WA, Lu HC, Yang A, Roberts K, DeSouza P, McGeehan KP, Mao DD, Sinha N, Ippolito JE, Dahiya S, Petti A, Yano H, Klisch TJ, Harmanci AS, Patel AJ, Kim AH. " NF2 loss-of-function and hypoxia drive radiation resistance in grade 2 meningiomas. " J Natl Cancer Inst. 2025 Jun 1; 117 (6) : 1175-1187.
Pubmed PMID: 39886924.

Projects

GammaTile Surgically Targeted Radiation Therapy (STaRT) in Intracranial Brain Neoplasms (GTM-101): GT Medical Technologies, Inc.; Baylor College of Medicine, Houston, TX; Site Principal Investigator, Baylor College of Medicine (2023-present). Multicenter observational study of GammaTile Surgically Targeted Radiation Therapy (STaRT) in intracranial brain neoplasms.
ROADS: Post-Surgical Stereotactic Radiotherapy versus GammaTile for Newly Diagnosed Metastatic Brain Tumors (GTM-102): GT Medical Technologies, Inc.; Baylor College of Medicine, Houston, TX; Site Principal Investigator, Baylor College of Medicine (2024-2025). Phase 3 randomized controlled trial of post-surgical stereotactic radiotherapy (SRT) versus Surgically Targeted Radiation Therapy with GammaTile for newly diagnosed metastatic brain tumors.
Single-Fraction versus Fractionated Post-Surgical Stereotactic Radiosurgery for Resected Brain Metastases (Alliance A071801): Alliance for Clinical Trials in Oncology; Baylor College of Medicine, Houston, TX; Site Principal Investigator, Baylor College of Medicine (2021-2022). Phase III trial comparing post-surgical single-fraction stereotactic radiosurgery (SRS) with fractionated SRS for resected metastatic brain disease.

Memberships

Congress of Neurological Surgeons: Executive Committee; 2027 Annual Meeting Chair; Education Committee Chair & Senior Advisor (01/2007)

American Association of Neurological Surgeons: Fellow (01/2007)

Texas Association of Neurological Surgeons: Vice President (01/2008)

North American Skull Base Society: Member (01/2017)

American Academy of Neurological Surgery: Member

Society of Neurological Surgeons: Executive Council; Chair, Medical Student Committee

American Association of South Asian Neurosurgeons: Secretary

AANS/CNS Section on Tumors: Executive Committee; Education Subcommittee

Funding

Establishing the Genomic Landscape of Human Atypical Meningiomas #K08NS102474: (07/01/2017 - 06/30/2022); Grant funding from NIH

Understanding the Epigenetic Drivers of Gene Expression Subtypes of Human Meningiomas #19RDM005: (11/01/2019 - 12/01/2020); Grant funding from Roderick D. MacDonald Research Grant

Establishing the Genomic Landscape of Human Atypical Meningiomas #16RDM004: (01/01/2017 - 12/31/2017); Grant funding from Roderick D. MacDonald Research Grant

Decoding Cellular Heterogeneity of Malignant Glioma #5-RP160192: (07/01/2015 - 06/01/2018); Grant funding from Cancer Prevention & Research Institute of Texas

Identifying the Biological Determinants of Aggressive Meningioma #RP240263: Grant funding from Cancer Prevention & Research Institute of Texas (CPRIT); Principal Investigator (2024-2027)

Harnessing Anti-Meningioma Immunity #NW 73990-I: Grant funding from Helis Medical Research Foundation; Co-Principal Investigator (2024-2027)

Genomic and Biochemical Mechanisms Underlying Meningioma Race Disparity Across Social and Structural Drivers of Health #1U54CA302452-01: Grant funding from National Cancer Institute (NCI); Co-Investigator (PI: David Raleigh) (2025-2030)

Intellectual Property

Systems and Methods for Identifying Molecular Groups of Meningioma Using Radiographic and Radiomic Features: Method Patent (Pending); Patent application filed June 2024.; Co Inventors: Tiemo Klisch

Languages

Gujarati