Journal Articles — Thomas Lloyd, M.D., Ph.D.

Dr. Thomas Lloyd has authored and co-authored 119 journal articles. They are listed here in reverse chronological order and grouped by published year. Click on the Expand plus symbol or Collapse minus symbol symbol to expand/collapse the list of journal publications by year, respectively.

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2024

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Journal Articles Published in 2024 (n = 1)

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Mathias K, Konig MF, Lloyd T, Albayda J. Sarcoid myopathy: an insidious diagnosis that can mimic inclusion body myositis. Rheumatology (Oxford). 2024;:. PMID: 38466916.

2023

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Journal Articles Published in 2023 (n = 12)

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Berth SH, Lloyd TE. Disruption of axonal transport in neurodegeneration. J Clin Invest. 2023;133(11):. PMID: 37259916.

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Casal-Dominguez M, Pinal-Fernandez I, Pak K, Muñoz-Braceras S, Milisenda JC, Torres-Ruiz J, et al. Coordinated local RNA overexpression of complement induced by interferon gamma in myositis. Sci Rep. 2023;13(1):2038. PMID: 36739295.

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Fridman V, Sillau S, Bockhorst J, Smith K, Moroni I, Pagliano E, et al. Disease progression in Charcot-Marie-Tooth disease related to MPZ mutations: A longitudinal study. Ann Neurol. 2023;93(3):563-76. PMID: 36203352.

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Hosono Y, Sie B, Pinal-Fernandez I, Pak K, Mecoli CA, Casal-Dominguez M, et al. Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1? autoantibodies. Ann Rheum Dis. 2023;82(2):246-52. PMID: 36008132.

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Machado PM, McDermott MP, Blaettler T, Sundgreen C, Amato AA, Ciafaloni E, et al. Safety and efficacy of arimoclomol for inclusion body myositis: A multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2023;22(10):900-11. PMID: 37739573.

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Michelle EH, Pinal-Fernandez I, Casal-Dominguez M, Albayda J, Paik JJ, Tiniakou E, et al. Clinical subgroups and factors associated with progression in patients with inclusion body myositis. Neurology. 2023;100(13):e1406-17. PMID: 36690456.

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Milisenda JC, Pinal-Fernandez I, Lloyd TE, Grau-Junyent JM, Christopher-Stine L, Corse AM, et al. The pattern of MHC class I expression in muscle biopsies from patients with myositis and other neuromuscular disorders. Rheumatology (Oxford). 2023;62(9):3156-60. PMID: 36707996.

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Pinal-Fernandez I, Milisenda JC, Pak K, Muñoz-Braceras S, Casal-Dominguez M, Torres-Ruiz J, et al. Transcriptional derepression of CHD4/NuRD-regulated genes in the muscle of patients with dermatomyositis and anti-Mi2 autoantibodies. Ann Rheum Dis. 2023;82(8):1091-7. PMID: 37130727.

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Pinal-Fernandez I, Quintana A, Milisenda JC, Casal-Dominguez M, Muñoz-Braceras S, Derfoul A, et al. Transcriptomic profiling reveals distinct subsets of immune checkpoint inhibitor induced myositis. Ann Rheum Dis. 2023;82(6):829-36. PMID: 36801811.

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Record CJ, Skorupinska M, Laura M, Rossor AM, Pareyson D, Pisciotta C, et al. Genetic analysis and natural history of Charcot-Marie-Tooth disease CMTX1 due to GJB1 variants. Brain. 2023;146(10):4336-49. PMID: 37284795.

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Roy B, Lucchini M, Lilleker JB, Goyal NA, Naddaf E, Adler B, et al. Current status of clinical outcome measures in inclusion body myositis: a systematised review. Clin Exp Rheumatol. 2023;41(2):370-8. PMID: 36762744.

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Sahana TG, Chase KJ, Liu F, Lloyd TE, Rossoll W, Zhang K. c-Jun N-terminal kinase promotes stress granule assembly and neurodegeneration in C9orf72-mediated ALS and FTD. J Neurosci. 2023;43(17):3186-97. PMID: 37015810.

2022

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Journal Articles Published in 2022 (n = 17)

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Angkeow JW, Monaco DR, Chen A, Venkataraman T, Jayaraman S, Valencia C, et al. Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses. Immunity. 2022;55(6):1051-66 e4. PMID: 35649416.

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Berth SH, Rich DJ, Lloyd TE. The role of autophagic kinases in regulation of axonal function. Front Cell Neurosci. 2022;16:996593. PMID: 36226074.

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Bourji KI, Mecoli CA, Paik JJ, Albayda J, Tiniakou E, Kelly W, et al. Prevalence of avascular necrosis in idiopathic inflammatory myopathies: A single-centre experience. Rheumatology (Oxford). 2022;61(3):936-42. PMID: 34175928.

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Britson KA, Ling JP, Braunstein KE, Montagne JM, Kastenschmidt JM, Wilson A, et al. Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis. Sci Transl Med. 2022;14(628):eabi9196. PMID: 35044790.

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Casal-Dominguez M, Pinal-Fernandez I, Pak K, Huang W, Selva-O'Callaghan A, Albayda J, et al. Performance of the 2017 European Alliance of Associations for Rheumatology/American College of Rheumatology classification criteria for idiopathic inflammatory myopathies in patients with myositis-specific autoantibodies. Arthritis Rheumatol. 2022;74(3):508-17. PMID: 34480833.

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Dubey SK, Maulding K, Sung H, Lloyd TE. Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD. Cell Rep. 2022;40(12):111379. PMID: 36130523.

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Fitzgerald KC, Mecoli CA, Douglas M, Harris S, Aravidis B, Albayda J, et al. Risk factors for infection and health impacts of the Coronavirus Disease 2019 (COVID-19) pandemic in people with autoimmune diseases. Clin Infect Dis. 2022;74(3):427-36. PMID: 33956972.

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Gao J, Mewborne QT, Girdhar A, Sheth U, Coyne AN, Punathil R, et al. Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Sci Transl Med. 2022;14(662):eabq3215. PMID: 36103513.

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Ikenaga C, Date H, Kanagawa M, Mitsui J, Ishiura H, Yoshimura J, et al. Muscle transcriptomics shows overexpression of cadherin 1 in inclusion body myositis. Ann Neurol. 2022;91(3):317-28. PMID: 35064929.

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Kim HJ, Mohassel P, Donkervoort S, Guo L, O'Donovan K, Coughlin M, et al. Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nat Commun. 2022;13(1):2306. PMID: 35484142.

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Korb M, Peck A, Alfano LN, Berger KI, James MK, Ghoshal N, et al. Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet J Rare Dis. 2022;17(1):23. PMID: 35093159.

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Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, et al. Publisher Correction: Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2022;25(2):264. PMID: 34934204.

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McLeish E, Slater N, Sooda A, Wilson A, Coudert JD, Lloyd TE, et al. Inclusion body myositis: The interplay between ageing, muscle degeneration and autoimmunity. Best Pract Res Clin Rheumatol. 2022;36(2):101761. PMID: 35760741.

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Pinal-Fernandez I, Pak K, Gil-Vila A, Baucells A, Plotz B, Casal-Dominguez M, et al. Anti-cortactin autoantibodies are associated with key clinical features in adult myositis but are rarely present in juvenile myositis. Arthritis Rheumatol. 2022;74(2):358-64. PMID: 34313394.

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Schiava M, Ikenaga C, Villar-Quiles RN, Caballero-Avila M, Topf A, Nishino I, et al. Genotype-phenotype correlations in valosin-containing protein disease: a retrospective muticentre study. J Neurol Neurosurg Psychiatry. 2022;:. PMID: 35896379.

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Sun C, Kannan S, Choi IY, Lim H, Zhang H, Chen GS, et al. Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment. Cell Stem Cell. 2022;29(4):610-9 e5. PMID: 35395188.

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Sung H, Lloyd TE. Defective axonal transport of endo-lysosomes and dense core vesicles in a Drosophila model of C9-ALS/FTD. Traffic. 2022;23(9):430-41. PMID: 35908282.

<2021

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Journal Articles Published in <2021 (n = 89)

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Amato AA, Hanna MG, Machado PM, Badrising UA, Chinoy H, Benveniste O, et al. Efficacy and safety of bimagrumab in sporadic inclusion body myositis: Long-term extension of RESILIENT. Neurology. 2021;96(12):e1595-607. PMID: 33597289.

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Casal-Dominguez M, Pinal-Fernandez I, Derfoul A, Graf R, Michelle H, Albayda J, et al. The phenotype of myositis patients with anti-Ku autoantibodies. Semin Arthritis Rheum. 2021;51(4):728-34. PMID: 34144382.

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Fitzgerald KC, Mecoli CA, Douglas M, Harris S, Aravidis B, Albayda J, et al. Risk factors for infection and health impacts of the COVID-19 pandemic in people with autoimmune diseases. medRxiv. 2021;:. PMID: 33564774.

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Grunseich C, Sarkar N, Lu J, Owen M, Schindler A, Calabresi PA, et al. Improving the efficacy of exome sequencing at a quaternary care referral centre: novel mutations, clinical presentations and diagnostic challenges in rare neurogenetic diseases. J Neurol Neurosurg Psychiatry. 2021;92(11):1186-96. PMID: 34103343.

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Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, et al. Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021;24(12):1673-85. PMID: 34782793.

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Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, et al. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. 2021;184(3):689-708 e20. PMID: 33482083.

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McCray BA, Diehl E, Sullivan JM, Aisenberg WH, Zaccor NW, Lau AR, et al. Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nat Commun. 2021;12(1):1444. PMID: 33664271.

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Milisenda JC, Pinal-Fernandez I, Lloyd TE, Grau JM, Miller FW, Selva-O'Callaghan A, et al. Accumulation of autophagosome cargo protein p62 is common in idiopathic inflammatory myopathies. Clin Exp Rheumatol. 2021;39(2):351-6. PMID: 32896253.

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NeuroLINCS Consortium , Li J, Lim RG, Kaye JA, Dardov V, Coyne AN, et al. An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. iScience. 2021;24(11):103221. PMID: 34746695.

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Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, et al. UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Rep. 2021;34(13):108925. PMID: 33789100.

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Azola A, Mulheren R, McKeon G, Lloyd T, Christopher-Stine L, Palmer J, et al. Dysphagia in myositis: A study of the structural and physiologic changes resulting in disordered swallowing. Am J Phys Med Rehabil. 2020;99(5):404-8. PMID: 31764229.

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Berth SH, Lloyd TE. Secondary causes of myositis. Curr Treat Options Neurol. 2020;22(11):38. PMID: 33041620.

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Bis-Brewer DM, Gan-Or Z, Sleiman P, Inherited Neuropathy Consortium , Hakonarson H, Fazal S, et al. Assessing non-Mendelian inheritance in inherited axonopathies. Genet Med. 2020;22(12):2114-9. PMID: 32741968.

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Cunningham KM, Maulding K, Ruan K, Senturk M, Grima JC, Sung H, et al. TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. elife. 2020;9:. PMID: 33300868.

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Fridman V, Sillau S, Acsadi G, Bacon C, Dooley K, Burns J, et al. A longitudinal study of CMT1A using Rasch analysis based CMT neuropathy and examination scores. Neurology. 2020;94(9):e884-96. PMID: 32047073.

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Montagne JM, Zheng XA, Pinal-Fernandez I, Milisenda JC, Christopher-Stine L, Lloyd TE, et al. Ultra-efficient sequencing of T Cell receptor repertoires reveals shared responses in muscle from patients with myositis. EBioMedicine. 2020;59:102972. PMID: 32891935.

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Pinal-Fernandez I, Casal-Dominguez M, Derfoul A, Pak K, Miller FW, Milisenda JC, et al. Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis. Ann Rheum Dis. 2020;79(9):1234-42. PMID: 32546599.

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Pipis M, Feely SME, Polke JM, Skorupinska M, Perez L, Shy RR, et al. Natural history of Charcot-Marie-Tooth disease type 2A: A large international multicentre study. Brain. 2020;143(12):3589-602. PMID: 33415332.

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Roy B, Nowak RJ, Roda R, Khokhar B, Patwa HS, Lloyd T, et al. Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical care. J Neurol Sci. 2020;414:116930. PMID: 32460041.

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Woolums BM, McCray BA, Sung H, Tabuchi M, Sullivan JM, Ruppell KT, et al. TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2). Nat Commun. 2020;11(1):2679. PMID: 32471994.

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Amici DR, Pinal-Fernandez I, Pagkatipunan R, Mears A, de Lorenzo R, Tiniakou E, et al. Muscle endurance deficits in myositis patients despite normal manual muscle testing scores. Muscle Nerve. 2019;59(1):70-5. PMID: 30028529.

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Berth SH, Lloyd TE. How can an understanding of the C9orf72 gene translate into amyotrophic lateral sclerosis therapies? Expert Rev Neurother. 2019;19(10):895-7. PMID: 31233365.

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Britson KA, Black AD, Wagner KR, Lloyd TE. Performing human skeletal muscle xenografts in immunodeficient mice. J Vis Exp. 2019;(151):. PMID: 31566598.

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Hanna MG, Badrising UA, Benveniste O, Lloyd TE, Needham M, Chinoy H, et al. Safety and efficacy of intravenous bimagrumab in inclusion body myositis (RESILIENT): a randomised, double-blind, placebo-controlled phase 2b trial. Lancet Neurol. 2019;18(9):834-44. PMID: 31397289.

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Ho L, Zhao D, Ono K, Ruan K, Mogno I, Tsuji M, et al. Heterogeneity in gut microbiota drive polyphenol metabolism that influences ?-synuclein misfolding and toxicity. J Nutr Biochem. 2019;64:170-81. PMID: 30530257.

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Pinal-Fernandez I, Amici DR, Parks CA, Derfoul A, Casal-Dominguez M, Pak K, et al. Myositis autoantigen expression correlates with muscle regeneration but not autoantibody specificity. Arthritis Rheumatol. 2019;71(8):1371-6. PMID: 30861336.

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Pinal-Fernandez I, Casal-Dominguez M, Derfoul A, Pak K, Plotz P, Miller FW, et al. Identification of distinctive interferon gene signatures in different types of myositis. Neurology. 2019;93(12):e1193-e1204. PMID: 31434690.

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Tao F, Beecham GW, Rebelo AP, Blanton SH, Moran JJ, Lopez-Anido C, et al. Modifier gene candidates in Charcot-Marie-Tooth Disease type 1A: A case-only genome-wide association study. J Neuromuscul Dis. 2019;6(2):201-11. PMID: 30958311.

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Tao F, Beecham GW, Rebelo AP, Svaren J, Blanton SH, Moran JJ, et al. Variation in SIPA1L2 is correlated with phenotype modification in Charcot- Marie-Tooth Disease type 1A. Ann Neurol. 2019;85(3):316-30. PMID: 30706531.

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Thomas S, Ajroud-Driss S, Dimachkie MM, Gibbons C, Freeman R, Simpson DM, et al. Peripheral Neuropathy Research Registry: A prospective cohort. J Peripher Nerv Syst. 2019;24(1):39-47. PMID: 30629307.

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Britson KA, Yang SY, Lloyd TE. New developments in the genetics of inclusion body myositis. Curr Rheumatol Rep. 2018;20(5):26. PMID: 29611059.

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Machamer JB, Woolums BM, Fuller GG, Lloyd TE. FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons. Brain Res. 2018;1693(Pt A):55-66. PMID: 29625118.

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McCray BA, Hurst W, Crawford TO, Lloyd TE. Fifteen-year longitudinal follow-up of a patient with severe early-onset Charcot-Marie-Tooth disease type 2A. Muscle Nerve. 2018;57(5):E126-8. PMID: 29266326.

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Vogler TO, Wheeler JR, Nguyen ED, Hughes MP, Britson KA, Lester E, et al. TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle. Nature. 2018;563(7732):508-13. PMID: 30464263.

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Zhang K, Coyne AN, Lloyd TE. Drosophila models of amyotrophic lateral sclerosis with defects in RNA metabolism. Brain Res. 2018;1693(Pt A):109-20. PMID: 29752901.

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Zhang K, Daigle JG, Cunningham KM, Coyne AN, Ruan K, Grima JC, et al. Stress granule assembly disrupts nucleocytoplasmic transport. Cell. 2018;173(4):958-71 e17. PMID: 29628143.

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Amici DR, Pinal-Fernandez I, Mázala DA, Lloyd TE, Corse AM, Christopher-Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5(1):24. PMID: 28330496.

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Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, et al. Mutant huntingtin disrupts the nuclear pore complex. Neuron. 2017;94(1):93-107 e6. PMID: 28384479.

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Güttsches AK, Brady S, Krause K, Maerkens A, Uszkoreit J, Eisenacher M, et al. Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis. Ann Neurol. 2017;81(2):227-39. PMID: 28009083.

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Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, et al. Tdp-43 cryptic exons are highly variable between cell types. Mol Neurodegener. 2017;12(1):13. PMID: 28153034.

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Johnson C, Rosen P, Lloyd T, Horton M, Christopher-Stine L, Oddis CV, et al. Exploration of the MUC5B promoter variant and ILD risk in patients with autoimmune myositis. Respir Med. 2017;130:52-4. PMID: 29206633.

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Lloyd TE, Pinal-Fernandez I, Michelle EH, Christopher-Stine L, Pak K, Sacktor N, et al. Overlapping features of polymyositis and inclusion body myositis in HIV-infected patients. Neurology. 2017;88(15):1454-60. PMID: 28283597.

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Panosyan FB, Laura M, Rossor AM, Pisciotta C, Piscosquito G, Burns J, et al. Cross-sectional analysis of a large cohort with X-linked Charcot-Marie-Tooth disease (CMTX1). Neurology. 2017;89(9):927-35. PMID: 28768847.

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Pinal-Fernandez I, Casal-Dominguez M, Carrino JA, Lahouti AH, Basharat P, Albayda J, et al. Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity. Ann Rheum Dis. 2017;76(4):681-7. PMID: 27651398.

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Thomas HS, Brodsky MB, Ewen JB, Bergey GK, Lloyd TE, Haughey NJ, et al. Internal grant review to increase grant funding for junior investigators. Ann Neurol. 2017;82(4):497-502. PMID: 28869672.

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Tiniakou E, Pinal-Fernandez I, Lloyd TE, Albayda J, Paik J, Werner JL, et al. More severe disease and slower recovery in younger patients with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy. Rheumatology (Oxford). 2017;56(5):787-94. PMID: 28096458.

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Basharat P, Lahouti AH, Paik JJ, Albayda J, Pinal-Fernandez I, Bichile T, et al. Statin-induced anti-HMGCR-associated myopathy. J Am Coll Cardiol. 2016;68(2):234-5. PMID: 27386780.

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Bharadwaj R, Cunningham KM, Zhang K, Lloyd TE. FIG4 regulates lysosome membrane homeostasis independent of phosphatase function. Hum Mol Genet. 2016;25(4):681-92. PMID: 26662798.

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Chhabra A, Carrino JA, Farahani SJ, Thawait GK, Sumner CJ, Wadhwa V, et al. Whole-body MR neurography: Prospective feasibility study in polyneuropathy and Charcot-Marie-Tooth disease. J Magn Reson Imaging. 2016;44(6):1513-21. PMID: 27126998.

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Freund B, Maddali M, Lloyd TE. A case of Morvan syndrome mimicking amyotrophic lateral sclerosis with frontotemporal dementia. J Clin Neuromuscul Dis. 2016;17(4):207-11. PMID: 27224435.

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Lloyd TE, Christopher-Stine L, Pinal-Fernandez I, Tiniakou E, Petri M, Baer A, et al. Cytosolic 5'-nucleotidase 1A as a target of circulating autoantibodies in autoimmune diseases. Arthritis Care Res (Hoboken). 2016;68(1):66-71. PMID: 25892010.

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Price MA, Barghout V, Benveniste O, Christopher-Stine L, Corbett A, de Visser M, et al. Mortality and causes of death in patients with sporadic inclusion body myositis: Survey study based on the clinical experience of specialists in Australia, Europe and the USA. J Neuromuscul Dis. 2016;3(1):67-75. PMID: 27854208.

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Zhang K, Grima JC, Rothstein JD, Lloyd TE. Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD. Nucleus. 2016;7(2):132-7. PMID: 27116041.

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Fridman V, Bundy B, Reilly MM, Pareyson D, Bacon C, Burns J, et al. CMT subtypes and disease burden in patients enrolled in the Inherited Neuropathies Consortium natural history study: a cross-sectional analysis. J Neurol Neurosurg Psychiatry. 2015;86(8):873-8. PMID: 25430934.

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Mammen AL, Casciola-Rosen L, Christopher-Stine L, Lloyd TE, Wagner KR. Myositis-specific autoantibodies are specific for myositis compared to genetic muscle disease. Neurol Neuroimmunol Neuroinflamm. 2015;2(6):e172. PMID: 26668818.

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Paik JJ, Wigley FM, Lloyd TE, Corse AM, Casciola-Rosen L, Shah AA, et al. Spectrum of muscle histopathologic findings in forty-to scleroderma patients with weakness. Arthritis Care Res (Hoboken). 2015;67(10):1416-25. PMID: 25989455.

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Sanmaneechai O, Feely S, Scherer SS, Herrmann DN, Burns J, Muntoni F, et al. Genotype-phenotype characteristics and baseline natural history of heritable neuropathies caused by mutations in the MPZ gene. Brain. 2015;138(Pt 11):3180-92. PMID: 26310628.

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Wu MN, Lloyd TE. Drosophila models of neurologic disease. Exp Neurol. 2015;274(Pt A):1-3. PMID: 26566006.

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Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, et al. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 2015;525(7567):56-61. PMID: 26308891.

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Chung T, Prasad K, Lloyd TE. Peripheral neuropathy: clinical and electrophysiological considerations. Neuroimaging Clin N Am. 2014;24(1):49-65. PMID: 24210312.

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Herrmann DN, Horvath R, Sowden JE, Gonzalez M, Sanchez-Mejias A, Guan Z, et al. Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy. Am J Hum Genet. 2014;95(3):332-9. PMID: 25192047.

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Liu S, Lamaze A, Liu Q, Tabuchi M, Yang Y, Fowler M, et al. WIDE AWAKE mediates the circadian timing of sleep onset. Neuron. 2014;82(1):151-66. PMID: 24631345.

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Lloyd TE, Mammen AL, Amato AA, Weiss MD, Needham M, Greenberg SA. Evaluation and construction of diagnostic criteria for inclusion body myositis. Neurology. 2014;83(5):426-33. PMID: 24975859.

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Machamer JB, Collins SE, Lloyd TE. The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction. Hum Mol Genet. 2014;23(14):3810-22. PMID: 24569165.

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Roda RH, Schindler AB, Blackstone C, Mammen AL, Corse AM, Lloyd TE. Laing distal myopathy pathologically resembling inclusion body myositis. Ann Clin Transl Neurol. 2014;1(12):1053-8. PMID: 25574480.

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Wong CO, Chen K, Lin YQ, Chao Y, Duraine L, Lu Z, et al. A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 2014;84(4):764-77. PMID: 25451193.

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Bharadwaj R, Roy M, Ohyama T, Sivan-Loukianova E, Delannoy M, Lloyd TE, et al. Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. Development. 2013;140(3):627-38. PMID: 23293294.

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Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, et al. Top3beta is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nat Neurosci. 2013;16(9):1238-47. PMID: 23912945.

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Lloyd TE, Machamer J, O'Hara K, Kim JH, Collins SE, Wong MY, et al. The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini. Neuron. 2012;74(2):344-60. PMID: 22542187.

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Lloyd TE. Axonal transport disruption in peripheral nerve disease: From Jack's discoveries as a resident to recent contributions. J Peripher Nerv Syst. 2012;17 Suppl 3(0 3):46-51. PMID: 23279432.

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Mammen AL, Gaudet D, Brisson D, Christopher-Stine L, Lloyd TE, Leffell MS, et al. Increased frequency of DRB1*11:01 in anti-hydroxymethylglutaryl-coenzyme A reductase-associated autoimmune myopathy. Arthritis Care Res (Hoboken). 2012;64(8):1233-7. PMID: 22422616.

0     

Wadhwa V, Thakkar RS, Maragakis N, Höke A, Sumner CJ, Lloyd TE, et al. Sciatic nerve tumor and tumor-like lesions - uncommon pathologies. Skeletal Radiol. 2012;41(7):763-74. PMID: 22410805.

0     

Werner JL, Christopher-Stine L, Ghazarian SR, Pak KS, Kus JE, Daya NR, et al. Antibody levels correlate with creatine kinase levels and strength in anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy. Arthritis Rheum. 2012;64(12):4087-93. PMID: 22933019.

0     

Wong MY, Zhou C, Shakiryanova D, Lloyd TE, Deitcher DL, Levitan ES. Neuropeptide delivery to synapses by long-range vesicle circulation and sporadic capture. Cell. 2012;148(5):1029-38. PMID: 22385966.

0     

Lanson NA, Jr, Maltare A, King H, Smith R, Kim JH, et al. A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43. Hum Mol Genet. 2011;20(13):2510-23. PMID: 21487023.

0     

Lloyd TE, Taylor JP. Flightless flies: Drosophila models of neuromuscular disease. Ann N Y Acad Sci. 2010;1184:e1-20. PMID: 20329357.

0     

Lloyd TE. Novel therapeutic approaches for inclusion body myositis. Curr Opin Rheumatol. 2010;22(6):658-64. PMID: 20827206.

0     

Jordan JD, Lloyd T, Pardo-Villamizar C. Case 16: Chasing the dragon. MedGenMed. 2007;9(2):14. PMID: 17955070.

0     

Lloyd TE, Atkinson R, Wu MN, Zhou Y, Pennetta G, Bellen HJ. Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell. 2002;108(2):261-9. PMID: 11832215.

0     

Seto ES, Bellen HJ, Lloyd TE. When cell biology meets development: endocytic regulation of signaling pathways. Genes Dev. 2002;16(11):1314-36. PMID: 12050111.

0     

Verstreken P, Kjaerulff O, Lloyd TE, Atkinson R, Zhou Y, Meinertzhagen IA, et al. Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell. 2002;109(1):101-12. PMID: 11955450.

0     

Fergestad T, Wu MN, Schulze KL, Lloyd TE, Bellen HJ, Broadie K. Targeted mutations in the syntaxin H3 domain specifically disrupt SNARE complex function in synaptic transmission. J Neurosci. 2001;21(23):9142-50. PMID: 11717347.

0     

Lloyd TE, Bellen HJ. pRIMing synaptic vesicles for fusion. Nat Neurosci. 2001;4(10):965-6. PMID: 11574826.

0     

Wu MN, Schulze KL, Lloyd TE, Bellen HJ. The ROP-syntaxin interaction inhibits neurotransmitter release. Eur J Cell Biol. 2001;80(2):196-9. PMID: 11302525.

0     

Lloyd TE, Verstreken P, Ostrin EJ, Phillippi A, Lichtarge O, Bellen HJ. A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron. 2000;26(1):45-50. PMID: 10798391.

0     

Mao Y, Nickitenko A, Duan X, Lloyd TE, Wu MN, Bellen H, et al. Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Cell. 2000;100(4):447-56. PMID: 10693761.

0     

Wu MN, Fergestad T, Lloyd TE, He Y, Broadie K, Bellen HJ. Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo. Neuron. 1999;23(3):593-605. PMID: 10433270.

0     

Lloyd TE, Yang L, Tang DN, Bennett T, Schober W, Lewis DE. Regulation of CD28 costimulation in human CD8+ T cells. J Immunol. 1997;158(4):1551-8. PMID: 9029089.

0     

Jeevan A, Bucana CD, Dong Z, Dizon VV, Thomas SL, Lloyd TE, et al. Ultraviolet radiation reduces phagocytosis and intracellular killing of mycobacteria and inhibits nitric oxide production by macrophages in mice. J Leukoc Biol. 1995;57(6):883-90. PMID: 7790771.

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