Journal Articles — Rachelle S. Doody, M.D., Ph.D.

Dr. Rachelle S. Doody has authored and co-authored 187 journal articles. They are listed here in reverse chronological order and grouped by published year. Click on the Expand plus symbol or Collapse minus symbol symbol to expand/collapse the list of journal publications by year, respectively.

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2022

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Journal Articles Published in 2022 (n = 2)

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Ostrowitzki S, Bittner T, Sink KM, Mackey H, Rabe C, Honig LS, et al. Evaluating the safety and efficacy of crenezumab vs placebo in adults with early Alzheimer disease: Two phase 3 randomized placebo-controlled trials. JAMA Neurol. 2022;79(11):1113-21. PMID: 36121669.

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Pavlik VN, Burnham SC, Kass JS, Helmer C, Palmqvist S, Vassilaki M, et al. Connecting Cohorts to Diminish Alzheimer's Disease (CONCORD-AD): A report of an international research collaboration network. J Alzheimers Dis. 2022;85(1):31-45. PMID: 34776434.

<2021

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Journal Articles Published in <2021 (n = 185)

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Fu X, Yu W, Ke M, Wang X, Zhang J, Luo T, et al. Chinese version of the Baylor Profound Mental Status Examination: A brief staging measure for patients with severe Alzheimer's disease. J Prev Alzheimers Dis. 2021;8(2):175-80. PMID: 33569564.

0     

Sood A, Pavlik V, Darby E, Chan W, Doody R. Different cognitive profiles are associated with progression rate and age at death in probable Alzheimer's disease. J Alzheimers Dis. 2021;80(2):735-47. PMID: 33579838.

0     

Balsis S, Geraci L, Benge J, Lowe DA, Choudhury TK, Tirso R, et al. Statistical model of dynamic markers of the Alzheimer's pathological cascade. J Gerontol B Psychol Sci Soc Sci. 2018;73(6):964-73. PMID: 29741663.

6

Jia J, Wei C, Jia L, Tang Y, Liang J, Zhou A, et al. Efficacy and safety of donepezil in Chinese patients with severe Alzheimer's disease: A randomized controlled trial. J Alzheimers Dis. 2017;56(4):1495-504. PMID: 28157100.

18

Li K, Chan W, Doody RS, Quinn J, Luo S, Alzheimer's Disease Neuroimaging Initiative. Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data. J Alzheimers Dis. 2017;58(2):361-71. PMID: 28436391.

9

Nave S, Doody RS, Boada M, Grimmer T, Savola JM, Delmar P, et al. Sembragiline in moderate Alzheimer's disease: Results of a randomized, double-blind, placebo-controlled phase ii trial (MAyflOwer RoAD). J Alzheimers Dis. 2017;58(4):1217-28. PMID: 28550255.

21

Woodward MR, Amrutkar CV, Shah HC, Benedict RH, Rajakrishnan S, Doody RS, et al. Validation of olfactory deficit as a biomarker of Alzheimer disease. Neurol Clin Pract. 2017;7(1):5-14. PMID: 28243501.

1

Alverson WA, Massman PJ, Doody RS. Prevalence and correlates of cognitive asymmetry in a large sample of Alzheimer's disease patients. J Clin Exp Neuropsychol. 2016;38(5):516-26. PMID: 26757777.

5

Bang J, Lobach IV, Lang AE, Grossman M, Knopman DS, Miller BL, et al. Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials. Parkinsonism Relat Disord. 2016;28:41-8. PMID: 27172829.

4

Benoit JS, Chan W, Luo S, Yeh HW, Doody R. A hidden Markov model approach to analyze longitudinal ternary outcomes when some observed states are possibly misclassified. Stat Med. 2016;35(9):1549-57. PMID: 26782946.

3

Doody RS, D'Amico S, Cutler AJ, Davis CS, Shin P, Ledon F, et al. An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results. CNS Spectr. 2016;21(6):450-9. PMID: 26471212.

10

Gordon MF, Lenderking WR, Duhig A, Chandler J, Lundy JJ, Miller DS, et al. Development of a patient-reported outcome instrument to assess complex activities of daily living and interpersonal functioning in persons with mild cognitive impairment: The qualitative research phase. Alzheimers Dement. 2016;12(1):75-84. PMID: 26079412.

0     

Hammond FM, Alexander DN, Cutler AJ, D'Amico S, Doody RS, Sauve W, et al. Erratum to: PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurol. 2016;16(1):160. PMID: 27590297.

15

Hammond FM, Alexander DN, Cutler AJ, D'Amico S, Doody RS, Sauve W, et al. PRISM II: An open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurol. 2016;16(1):89. PMID: 27276999.

2

Liang FW, Chan W, Chen PJ, Zimmerman C, Waring S, Doody R. Cognitively-related basic activities of daily living impairment greatly increases the risk of death in Alzheimers disease. PLoS One. 2016;11(8):e0160671. PMID: 27571265.

3

Luo S, Chan W, Detry MA, Massman PJ, Doody RS. Binomial regression with a misclassified covariate and outcome. Stat Methods Med Res. 2016;25(1):101-17. PMID: 22421539.

9

Doody RS, Demirovic J, Ballantyne CM, Chan W, Barber R, Powell S, et al. Lipoprotein-associated phospholipase A2, homocysteine, and Alzheimer's disease. Alzheimers Dement (Amst). 2015;1(4):464-71. PMID: 27239525.

0     

Doody RS, Raman R, Sperling RA, Seimers E, Sethuraman G, Mohs R, et al. Peripheral and central effects of gamma-secretase inhibition by semagacestat in Alzheimer's disease. Alzheimers Res Ther. 2015;7(1):36. PMID: 26064192.

9

Grill JD, Raman R, Ernstrom K, Aisen P, Dowsett SA, Chen YF, et al. Comparing recruitment, retention, and safety reporting among geographic regions in multinational Alzheimer's disease clinical trials. Alzheimers Res Ther. 2015;7(1):39. PMID: 26120368.

12

Henley DB, Dowsett SA, Chen YF, Liu-Seifert H, Grill JD, Doody RS, et al. Alzheimer's disease progression by geographical region in a clinical trial setting. Alzheimers Res Ther. 2015;7(1):43. PMID: 26120369.

0     

 

Liu-Seifert H, Siemers E, Holdridge KC, Andersen SW, Lipkovich I, Carlson C, et al. Delayed-start analysis: Mild Alzheimer's disease patients in solanezumab trials, 3.5 years. Alzheimers Dement (N Y). 2015;1(2):111-21. DOI: 10.1016/j.trci.2015.06.006.

4

Lowe DA, Balsis S, Benge JF, Doody RS. Adding delayed recall to the ADAS-cog improves measurement precision in mild Alzheimer's disease: Implications for predicting instrumental activities of daily living. Psychol Assess. 2015;27(4):1234-40. PMID: 25938338.

3

Salmeron S, Huedo I, Lopez-Utiel M, Soler-Moratalla I, Flores-Ruano T, Fernandez-Sanchez M, et al. Validation of the Spanish Version of the Baylor Profound Mental Status Examination. J Alzheimers Dis. 2015;49(1):73-8. PMID: 26444781.

0     

 

Vellas B, Bateman R, Blennow K, Frisoni G, Johnson K, Katz R, et al. Endpoints for pre-dementia ad trials: A report from the EU/US/CTAD task force. J Prev Alz Dis. 2015;2(2):128-35.

133

Boxer AL, Lang AE, Grossman M, Knopman DS, Miller BL, Schneider LS, et al. Davunetide in patients with progressive supranuclear palsy: A randomised, double-blind, placebo-controlled phase 2/3 trial. Lancet Neurol. 2014;13(7):676-85. PMID: 24873720.

41

Doody RS, Farlow M, Aisen PS, Alzheimer's Disease Cooperative Study Data Analysis and Publication Committee. Phase 3 trials of solanezumab and bapineuzumab for Alzheimer's disease. N Engl J Med. 2014;370(15):1460. PMID: 24716687.

774

Doody RS, Thomas RG, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med. 2014;370(4):311-21. PMID: 24450890.

8

O'Bryant SE, Xiao G, Barber R, Cullum CM, Weiner M, Hall J, et al. Molecular neuropsychology: Creation of test-specific blood biomarker algorithms. Dement Geriatr Cogn Disord. 2014;37(1-2):45-57. PMID: 24107792.

8

Szigeti K, Kellermayer B, Lentini JM, Trummer B, Lal D, Doody RS, et al. Ordered subset analysis of copy number variation association with age at onset of Alzheimer's disease. J Alzheimers Dis. 2014;41(4):1063-71. PMID: 24787912.

5

Doody RS, Aisen PS, Iwatsubo T. Semagacestat for treatment of Alzheimer's disease. N Engl J Med. 2013;369(17):1661. PMID: 24152267.

530

Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. A phase 3 trial of semagacestat for treatment of Alzheimer's disease. N Engl J Med. 2013;369(4):341-50. PMID: 23883379.

10

Ferris S, Cummings J, Christensen D, Doody R, Farlow M, Sabbagh M, et al. Effects of donepezil 23 mg on Severe Impairment Battery domains in patients with moderate to severe Alzheimer's disease: Evaluating the impact of baseline severity. Alzheimers Res Ther. 2013;5(1):12. PMID: 23433097.

13

Pavlik V, Massman P, Barber R, Doody R. Differences in the association of peripheral insulin and cognitive function in non-diabetic Alzheimer's disease cases and normal controls. J Alzheimers Dis. 2013;34(2):449-56. PMID: 23241558.

50

Rountree SD, Atri A, Lopez OL, Doody RS. Effectiveness of antidementia drugs in delaying Alzheimer's disease progression. Alzheimers Dement. 2013;9(3):338-45. PMID: 23102979.

20

Sabbagh M, Cummings J, Christensen D, Doody R, Farlow M, Liu L, et al. Evaluating the cognitive effects of donepezil 23 mg/d in moderate and severe Alzheimer's disease: analysis of effects of baseline features on treatment response. BMC Geriatr. 2013;13:56. PMID: 23742728.

6

Senanarong V, Harnphadungkit K, Poungvarin N, Vannasaeng S, Chongwisal S, Chakorn T, et al. The dementia and disability project in Thai elderly: Rational, design, methodology and early results. BMC Neurol. 2013;13:3. PMID: 23305293.

2

Spiegel R, Doody RS, Hendrix S, Kahle-Wrobleski K. Modeling the course of Alzheimer's disease to improve clinical trials: Symposium report. Alzheimers Res Ther. 2013;5(3):29. PMID: 23767782.

17

Szigeti K, Lal D, Li Y, Doody RS, Wilhelmsen K, Yan L, et al. Genome-wide scan for copy number variation association with age at onset of Alzheimer's disease. J Alzheimers Dis. 2013;33(2):517-23. PMID: 23202439.

0     

Vellas B, Carrillo MC, Sampaio C, Brashear HR, Siemers E, Hampel H, et al. Designing drug trials for Alzheimer's disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force. Alzheimers Dement. 2013;9(4):438-44. PMID: 23809364.

34

Zhang X, Li L, Zhang X, Xie W, Li L, Yang D, et al. Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer's disease neuropathology in APPSwe/PS1A246E transgenic mice. Neurobiol Aging. 2013;34(3):663-78. PMID: 22795785.

16

Atri A, Rountree SD, Lopez OL, Doody RS. Validity, significance, strengths, limitations, and evidentiary value of real-world clinical data for combination therapy in Alzheimer's disease: comparison of efficacy and effectiveness studies. Neurodegener Dis. 2012;10(1-4):170-4. PMID: 22327239.

20

Balsis S, Unger AA, Benge JF, Geraci L, Doody RS. Gaining precision on the Alzheimer's Disease Assessment Scale-cognitive: a comparison of item response theory-based scores and total scores. Alzheimers Dement. 2012;8(4):288-94. PMID: 22465173.

18

Doody RS, Cummings JL, Farlow MR. Reviewing the role of donepezil in the treatment of Alzheimer's disease. Curr Alzheimer Res. 2012;9(7):773-81. PMID: 22175653.

28

Doody RS, Geldmacher DS, Farlow MR, Sun Y, Moline M, Mackell J. Efficacy and safety of donepezil 23 mg versus donepezil 10 mg for moderate-to-severe Alzheimer's disease: A subgroup analysis in patients already taking or not taking concomitant memantine. Dement Geriatr Cogn Disord. 2012;33(2-3):164-73. PMID: 22572767.

11

Havins WN, Massman PJ, Doody R. Factor structure of the Geriatric Depression Scale and relationships with cognition and function in Alzheimer's disease. Dement Geriatr Cogn Disord. 2012;34(5-6):360-72. PMID: 23235472.

4

Hurko O, Black SE, Doody R, Doraiswamy PM, Gamst A, Kaye J, et al. The ADNI Publication Policy: Commensurate recognition of critical contributors who are not authors. Neuroimage. 2012;59(4):4196-200. PMID: 22100665.

10

Li Y, Shaw CA, Sheffer I, Sule N, Powell SZ, Dawson B, et al. Integrated copy number and gene expression analysis detects a CREB1 association with Alzheimer's disease. Transl Psychiatry. 2012;2:e192. PMID: 23168992.

3

Lowe DA, Balsis S, Miller TM, Benge JF, Doody RS. Greater precision when measuring dementia severity: Establishing item parameters for the Clinical Dementia Rating Scale. Dement Geriatr Cogn Disord. 2012;34(2):128-34. PMID: 23006935.

34

Rountree SD, Chan W, Pavlik VN, Darby EJ, Doody RS. Factors that influence survival in a probable Alzheimer disease cohort. Alzheimers Res Ther. 2012;4(3):16. PMID: 22594761.

117

Aisen PS, Andrieu S, Sampaio C, Carrillo M, Khachaturian ZS, Dubois B, et al. Report of the task force on designing clinical trials in early (predementia) AD. Neurology. 2011;76(3):280-6. PMID: 21178097.

7

Balsis S, Miller TM, Benge JF, Doody RS. Dementia staging across three different methods. Dement Geriatr Cogn Disord. 2011;31(5):328-33. PMID: 21555887.

11

Doody RS, Cole PE, Miller DS, Siemers E, Black R, Feldman H, et al. Global issues in drug development for Alzheimer's disease. Alzheimers Dement. 2011;7(2):197-207. PMID: 21414556.

6

Doody RS, Ferris SH, Salloway S, Meuser TM, Murthy AK, Li C, et al. Identifying amnestic mild cognitive impairment in primary care: A feasibility study. Clin Drug Investig. 2011;31(7):483-91. PMID: 21627337.

68

Mielke MM, Haughey NJ, Bandaru VV, Weinberg DD, Darby E, Zaidi N, et al. Plasma sphingomyelins are associated with cognitive progression in Alzheimer's disease. J Alzheimers Dis. 2011;27(2):259-69. PMID: 21841258.

5

Miller TM, Balsis S, Lowe DA, Benge JF, Doody RS. Item response theory reveals variability of functional impairment within clinical dementia rating scale stages. Dement Geriatr Cogn Disord. 2011;32(5):362-6. PMID: 22311305.

99

O'Bryant SE, Xiao G, Barber R, Huebinger R, Wilhelmsen K, Edwards M, et al. A blood-based screening tool for Alzheimer's disease that spans serum and plasma: Findings from TARC and ADNI. PLoS One. 2011;6(12):e28092. PMID: 22163278.

63

O'Bryant SE, Xiao G, Barber R, Reisch J, Hall J, Cullum CM, et al. A blood-based algorithm for the detection of Alzheimer's disease. Dement Geriatr Cogn Disord. 2011;32(1):55-62. PMID: 21865746.

2

Pavlik VN, Doody RS. Progress in understanding variability in cognitive responses to cholinesterase inhibitor treatment. Alzheimers Res Ther. 2011;3(5):30. PMID: 21999183.

30

Shaw CA, Li Y, Wiszniewska J, Chasse S, Zaidi SN, Jin W, et al. Olfactory copy number association with age at onset of Alzheimer disease. Neurology. 2011;76(15):1302-9. PMID: 21482944.

0     

Szigeti K, Doody RS. Should EOAD patients be included in clinical trials? Alzheimers Res Ther. 2011;3(1):4. PMID: 21345175.

0     

Szigeti K, Doody RS. Should persons with autosomal dominant AD be included in clinical trials? Authors' response. Alzheimers Res Ther. 2011;3(3):19. PMID: 21631907.

62

Zhang X, Heng X, Li T, Li L, Yang D, Zhang X, et al. Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer's disease transgenic mouse model. J Alzheimers Dis. 2011;24(4):739-49. PMID: 21321394.

9

Doody RS, Ferris S, Salloway S, Yijun S, Goldman R, Yikang X, et al. Safety and tolerability of donepezil in mild cognitive impairment: Open-label extension study. Am J Alzheimers Dis Other Demen. 2010;25(2):155-9. PMID: 19949165.

0     

Doody RS, Pavlik V, Massman P, Rountree S, Darby E, Chan W. Correction: Predicting progression of Alzheimer's disease. Alzheimers Res Ther. 2010;2(3):14. PMID: 20470369.

62

Doody RS, Pavlik V, Massman P, Rountree S, Darby E, Chan W. Predicting progression of Alzheimer's disease. Alzheimers Res Ther. 2010;2(1):2. PMID: 20178566.

0     

Doody RS. Clinical trials in AD. Rinsho Shinkeigaku. 2010;50(11):835. PMID: 21921461.

6

Doody RS. Evolving early (pre-dementia) Alzheimer's disease trials: Suit the outcomes to the population and study design. J Nutr Health Aging. 2010;14(4):299-302. PMID: 20306000.

287

Feldman HH, Doody RS, Kivipelto M, Sparks DL, Waters DD, Jones RW, et al. Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe. Neurology. 2010;74(12):956-64. PMID: 20200346.

41

Kunik ME, Snow AL, Davila JA, McNeese T, Steele AB, Balasubramanyam V, et al. Consequences of aggressive behavior in patients with dementia. J Neuropsychiatry Clin Neurosci. 2010;22(1):40-7. PMID: 20160208.

70

Kunik ME, Snow AL, Davila JA, Steele AB, Balasubramanyam V, Doody RS, et al. Causes of aggressive behavior in patients with dementia. J Clin Psychiatry. 2010;71(9):1145-52. PMID: 20361896.

17

Kwon OD, Khaleeq A, Chan W, Pavlik VN, Doody RS. Apolipoprotein E polymorphism and age at onset of Alzheimer's disease in a quadriethnic sample. Dement Geriatr Cogn Disord. 2010;30(6):486-91. PMID: 21252542.

160

O'Bryant SE, Xiao G, Barber R, Reisch J, Doody R, Fairchild T, et al. A serum protein-based algorithm for the detection of Alzheimer disease. Arch Neurol. 2010;67(9):1077-81. PMID: 20837851.

0     

Wolk DA, Dickerson BC, Alzheimer's Disease Neuroimaging Initiative. Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease. Proc Natl Acad Sci U S A. 2010;107(22):10256-61. PMID: 20479234.

32

Benge JF, Balsis S, Geraci L, Massman PJ, Doody RS. How well do the ADAS-cog and its subscales measure cognitive dysfunction in Alzheimer's disease? Dement Geriatr Cogn Disord. 2009;28(1):63-9. PMID: 19641319.

145

Doody RS, Ferris SH, Salloway S, Sun Y, Goldman R, Watkins WE, et al. Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial. Neurology. 2009;72(18):1555-61. PMID: 19176895.

4

Doody RS. Commentary on "a roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Centers of excellence in Alzheimer's disease: It is time to better integrate patient care and clinical research to improve the prevention and treatment of Alzheimer's disease. Alzheimers Dement. 2009;5(2):133-6. PMID: 19328443.

7

Doody RS. Dimebon as a potential therapy for Alzheimer's disease. CNS Spectr. 2009;14(8 Suppl 7):14-6; discussion 16-8. PMID: 19890242.

0     

Khachaturian ZS, Snyder PJ, Doody R, Aisen P, Comer M, Dwyer J, et al. A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement. 2009;5(2):85-92. PMID: 19328434.

10

Na HR, Lee SH, Lee JS, Doody RS, Kim SY. Korean version of the Baylor Profound Mental Status Examination: A brief staging measure for patients with severe Alzheimer's disease. Dement Geriatr Cogn Disord. 2009;27(1):69-75. PMID: 19145080.

20

Pavlik VN, Doody RS, Rountree SD, Darby EJ. Vitamin E use is associated with improved survival in an Alzheimer's disease cohort. Dement Geriatr Cogn Disord. 2009;28(6):536-40. PMID: 20016184.

0     

Rountree SD, Chan W, Pavlik VN, Darby EJ, Siddiqui S, Doody RS. Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease. Alzheimers Res Ther. 2009;1(2):7. PMID: 19845950.

527

Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology. 2009;73(24):2061-70. PMID: 19923550.

15

Schneider LS, Raman R, Schmitt FA, Doody RS, Insel P, Clark CM, et al. Characteristics and performance of a modified version of the ADCS-CGIC CIBIC+ for mild cognitive impairment clinical trials. Alzheimer Dis Assoc Disord. 2009;23(3):260-7. PMID: 19812469.

8

Snyder PJ, Papp KV, Bartkowiak J, Jackson CE, Doody RS. Commentary on "A roadmap for the prevention of dementia II. Leon Thal Symposium 2008." Recruitment of participants for Alzheimer's disease clinical trials: The role of trust in caregivers, clinical researchers, regulatory authorities, and industry sponsors. Alzheimers Dement. 2009;5(2):122-4. PMID: 19328439.

27

Doody RS, Corey-Bloom J, Zhang R, Li H, Ieni J, Schindler R. Safety and tolerability of donepezil at doses up to 20 mg/day: Results from a pilot study in patients with Alzheimer's disease. Drugs Aging. 2008;25(2):163-74. PMID: 18257603.

384

Doody RS, Gavrilova SI, Sano M, Thomas RG, Aisen PS, Bachurin SO, et al. Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: A randomized, double-blind, placebo-controlled study. Lancet. 2008;372(9634):207-15. PMID: 18640457.

73

 

Doody RS, Tariot PN, Pfeiffer E, Olin JT, Graham SM. Meta-analysis of six-month memantine trials in Alzheimer's disease. Alzheimers Dement. 2008;3(1):7-17.

9

Doody RS. Cholinesterase inhibitors and memantine: Best practices. CNS Spectr. 2008;13(10 Suppl 16):34-5. PMID: 18955960.

13

Doody RS. We should not distinguish between symptomatic and disease-modifying treatments in Alzheimer's disease drug development. Alzheimers Dement. 2008;4(1 Suppl 1):S21-5. PMID: 18631995.

108

Jack CR, Jr, Petersen RC, Grundman M, Jin S, Gamst A, et al. Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI. Neurobiol Aging. 2008;29(9):1285-95. PMID: 17452062.

51

Jones RW, Kivipelto M, Feldman H, Sparks L, Doody R, Waters DD, et al. The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): Design and baseline characteristics. Alzheimers Dement. 2008;4(2):145-53. PMID: 18631958.

21

Kelly PA, Dyer CB, Pavlik V, Doody R, Jogerst G. Exploring self-neglect in older adults: Preliminary findings of the self-neglect severity scale and next steps. J Am Geriatr Soc. 2008;56 Suppl 2:S253-60. PMID: 19016968.

40

Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, et al. A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium. Alzheimers Dement. 2008;4(3):156-63. PMID: 18631960.

255

O'Bryant SE, Waring SC, Cullum CM, Hall J, Lacritz L, Massman PJ, et al. Staging dementia using Clinical Dementia Rating Scale Sum of Boxes scores: a Texas Alzheimer's research consortium study. Arch Neurol. 2008;65(8):1091-5. PMID: 18695059.

74

Yan JH, Rountree S, Massman P, Doody RS, Li H. Alzheimer's disease and mild cognitive impairment deteriorate fine movement control. J Psychiatr Res. 2008;42(14):1203-12. PMID: 18280503.

24

Atchison TB, Massman PJ, Doody RS. Baseline cognitive function predicts rate of decline in basic-care abilities of individuals with dementia of the Alzheimer's type. Arch Clin Neuropsychol. 2007;22(1):99-107. PMID: 17174522.

182

Black SE, Doody R, Li H, McRae T, Jambor KM, Xu Y, et al. Donepezil preserves cognition and global function in patients with severe Alzheimer disease. Neurology. 2007;69(5):459-69. PMID: 17664405.

208

Cummings JL, Doody R, Clark C. Disease-modifying therapies for Alzheimer disease: challenges to early intervention. Neurology. 2007;69(16):1622-34. PMID: 17938373.

21

Park KW, Pavlik VN, Rountree SD, Darby EJ, Doody RS. Is functional decline necessary for a diagnosis of Alzheimer's disease? Dement Geriatr Cogn Disord. 2007;24(5):375-9. PMID: 17914262.

59

Rountree SD, Waring SC, Chan WC, Lupo PJ, Darby EJ, Doody RS. Importance of subtle amnestic and nonamnestic deficits in mild cognitive impairment: Prognosis and conversion to dementia. Dement Geriatr Cogn Disord. 2007;24(6):476-82. PMID: 17992015.

24

Dyer CB, Kelly PA, Pavlik VN, Lee J, Doody RS, Regev T, et al. The making of a self-neglect severity scale. J Elder Abuse Negl. 2006;18(4):13-23. PMID: 17972656.

0     

Fillit HM, Doody RS, Binaso K, Crooks GM, Ferris SH, Farlow MR, et al. Recommendations for best practices in the treatment of Alzheimer's disease in managed care. Am J Geriatr Pharmacother. 2006;4 Suppl A:S9-S24; quiz S25-S28. PMID: 17157793.

78

Geldmacher DS, Frolich L, Doody RS, Erkinjuntti T, Vellas B, Jones RW, et al. Realistic expectations for treatment success in Alzheimer's disease. J Nutr Health Aging. 2006;10(5):417-29. PMID: 17066215.

37

Pavlik VN, Doody RS, Massman PJ, Chan W. Influence of premorbid IQ and education on progression of Alzheimer's disease. Dement Geriatr Cogn Disord. 2006;22(4):367-77. PMID: 16954693.

136

Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ. A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease. Arch Neurol. 2006;63(1):49-54. PMID: 16401736.

29

Schneider LS, Clark CM, Doody R, Ferris SH, Morris JC, Raman R, et al. ADCS Prevention Instrument Project: ADCS-clinicians' global impression of change scales (ADCS-CGIC), self-rated and study partner-rated versions. Alzheimer Dis Assoc Disord. 2006;20(4 Suppl 3):S124-38. PMID: 17135806.

45

Doody R, Pavlik V, Massman P, Kenan M, Yeh S, Powell S, et al. Changing patient characteristics and survival experience in an Alzheimer's center patient cohort. Dement Geriatr Cogn Disord. 2005;20(2-3):198-208. PMID: 16088145.

13

Doody RS. Refining treatment guidelines in Alzheimer's disease. Geriatrics. 2005;Suppl:14-20. PMID: 16025771.

44

Graham DP, Kunik ME, Doody R, Snow AL. Self-reported awareness of performance in dementia. Brain Res Cogn Brain Res. 2005;25(1):144-52. PMID: 15919186.

56

Hoyt BD, Massman PJ, Schatschneider C, Cooke N, Doody RS. Individual growth curve analysis of APOE epsilon 4-associated cognitive decline in Alzheimer disease. Arch Neurol. 2005;62(3):454-9. PMID: 15767511.

54

Pavlik VN, Hyman DJ, Doody R. Cardiovascular risk factors and cognitive function in adults 30-59 years of age (NHANES III). Neuroepidemiology. 2005;24(1-2):42-50. PMID: 15459509.

1340

Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352(23):2379-88. PMID: 15829527.

80

Roman GC, Wilkinson DG, Doody RS, Black SE, Salloway SP, Schindler RJ. Donepezil in vascular dementia: Combined analysis of two large-scale clinical trials. Dement Geriatr Cogn Disord. 2005;20(6):338-44. PMID: 16192723.

15

Snow AL, Graham DP, Molinari VA, Orengo CA, Doody RS, Norris MP, et al. Factors affecting deficit awareness in persons with dementia. Dement Geriatr Cogn Disord. 2005;20(2-3):133-9. PMID: 16020941.

53

Snow AL, Kunik ME, Molinari VA, Orengo CA, Doody R, Graham DP, et al. Accuracy of self-reported depression in persons with dementia. J Am Geriatr Soc. 2005;53(3):389-96. PMID: 15743279.

72

Waring SC, Doody RS, Pavlik VN, Massman PJ, Chan W. Survival among patients with dementia from a large multi-ethnic population. Alzheimer Dis Assoc Disord. 2005;19(4):178-83. PMID: 16327343.

44

Doody R, Wirth Y, Schmitt F, Mobius HJ. Specific functional effects of memantine treatment in patients with moderate to severe Alzheimer's disease. Dement Geriatr Cogn Disord. 2004;18(2):227-32. PMID: 15256834.

29

Doody RS, Dunn JK, Huang E, Azher S, Kataki M. A method for estimating duration of illness in Alzheimer's disease. Dement Geriatr Cogn Disord. 2004;17(1-2):1-4. PMID: 14560058.

39

Graham DP, Cully JA, Snow AL, Massman P, Doody R. The Alzheimer's Disease Assessment Scale-Cognitive subscale: Normative data for older adult controls. Alzheimer Dis Assoc Disord. 2004;18(4):236-40. PMID: 15592137.

635

Grundman M, Petersen RC, Ferris SH, Thomas RG, Aisen PS, Bennett DA, et al. Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol. 2004;61(1):59-66. PMID: 14732621.

33

Snow AL, Norris MP, Doody R, Molinari VA, Orengo CA, Kunik ME. Dementia Deficits Scale. Rating self-awareness of deficits. Alzheimer Dis Assoc Disord. 2004;18(1):22-31. PMID: 15198084.

285

Clark CM, Xie S, Chittams J, Ewbank D, Peskind E, Galasko D, et al. Cerebrospinal fluid tau and beta-amyloid: How well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol. 2003;60(12):1696-702. PMID: 14676043.

14

Davis RN, Massman PJ, Doody RS. Effects of blood pressure on neuropsychological functioning in Alzheimer's disease. Arch Clin Neuropsychol. 2003;18(1):19-32. PMID: 14591475.

11

Davis RN, Massman PJ, Doody RS. WAIS-R factor structure in Alzheimer's disease patients: A comparison of alternative models and an assessment of their generalizability. Psychol Aging. 2003;18(4):836-43. PMID: 14692868.

66

Doody RS. Current treatments for Alzheimer's disease: Cholinesterase inhibitors. J Clin Psychiatry. 2003;64 Suppl 9:11-7. PMID: 12934969.

6

Doody RS. Update on Alzheimer drugs (donepezil). Neurologist. 2003;9(5):225-9. PMID: 12971832.

1537

Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ, et al. Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med. 2003;348(14):1333-41. PMID: 12672860.

0     

 

Smith RG, Roher AE, Appel SH, Doody RS, Killian JM, Corey-Bloom J, et al. Autonomic sudomotor dysfunction in Alzheimer's disease. Curr Med Chem - Imun Endoc Metab Agents. 2003;3(1):77-84.

273

Wilkinson D, Doody R, Helme R, Taubman K, Mintzer J, Kertesz A, et al. Donepezil in vascular dementia: a randomized, placebo-controlled study. Neurology. 2003;61(4):479-86. PMID: 12939421.

37

Quinn J, Moore M, Benson DF, Clark CM, Doody R, Jagust W, et al. A videotaped CIBIC for dementia patients: Validity and reliability in a simulated clinical trial. Neurology. 2002;58(3):433-7. PMID: 11839844.

35

Weiner MF, Doody RS, Sairam R, Foster B, Liao TY. Prevalence and incidence of major depressive disorder in Alzheimer's disease: findings from two databases. Dement Geriatr Cogn Disord. 2002;13(1):8-12. PMID: 11731709.

167

Davis RN, Massman PJ, Doody RS. Cognitive intervention in Alzheimer disease: a randomized placebo-controlled study. Alzheimer Dis Assoc Disord. 2001;15(1):1-9. PMID: 11236819.

105

Doody RS, Dunn JK, Clark CM, Farlow M, Foster NL, Liao T, et al. Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord. 2001;12(4):295-300. PMID: 11351141.

317

Doody RS, Geldmacher DS, Gordon B, Perdomo CA, Pratt RD. Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol. 2001;58(3):427-33. PMID: 11255446.

126

Doody RS, Massman P, Dunn JK. A method for estimating progression rates in Alzheimer disease. Arch Neurol. 2001;58(3):449-54. PMID: 11255449.

714

Doody RS, Stevens JC, Beck C, Dubinsky RM, Kaye JA, Gwyther L, et al. Practice parameter: Management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001;56(9):1154-66. PMID: 11342679.

446

Mohs RC, Doody RS, Morris JC, Ieni JR, Rogers SL, Perdomo CA, et al. A 1-year, placebo-controlled preservation of function survival study of donepezil in AD patients. Neurology. 2001;57(3):481-8. PMID: 11502917.

3314

Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, et al. Current concepts in mild cognitive impairment. Arch Neurol. 2001;58(12):1985-92. PMID: 11735772.

0     

Tangalos E, Doody R, Tariot P. Alzheimer's disease in long-term care: Maximizing treatment options. J Am Med Dir Assoc. 2001;2(4):H17-20. PMID: 12812557.

23

Doody RS, Azher SN, Haykal HA, Dunn JK, Liao T, Schneider L. Does APO epsilon4 correlate with MRI changes in Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2000;69(5):668-71. PMID: 11032626.

38

Doody RS. Mortality from pneumonia and hip fractures in patients with advanced dementia. Jama. 2000;284(19):2447; author reply 2448. PMID: 11074768.

0     

Doody RS. The issue of representation in brain research. Brain Cogn. 2000;42(1):26-8. PMID: 10739589.

10

Hanna PA, Doody RS. Alien limb sign. Adv Neurol. 2000;82:135-45. PMID: 10624477.

862

Mulnard RA, Cotman CW, Kawas C, van Dyck CH, Sano M, Doody R, et al. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. Jama. 2000;283(8):1007-15. PMID: 10697060.

227

Rogers SL, Doody RS, Pratt RD, Ieni JR. Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: Final analysis of a US multicentre open-label study. Eur Neuropsychopharmacol. 2000;10(3):195-203. PMID: 10793322.

16

Doody RS, Strehlow SL, Massman PJ, Feher EP, Clark C, Roy JR. Baylor profound mental status examination: A brief staging measure for profoundly demented Alzheimer disease patients. Alzheimer Dis Assoc Disord. 1999;13(1):53-9. PMID: 10192643.

21

Doody RS, Vacca JL, Massman PJ, Liao TY. The influence of handedness on the clinical presentation and neuropsychology of Alzheimer disease. Arch Neurol. 1999;56(9):1133-7. PMID: 10488815.

19

Doody RS. Clinical benefits of a new piperidine-class AChE inhibitor. Eur Neuropsychopharmacol. 1999;9 Suppl 2:S69-77. PMID: 10332937.

69

Doody RS. Clinical profile of donepezil in the treatment of Alzheimer's disease. Gerontology. 1999;45 Suppl 1:23-32. PMID: 9876215.

21

Doody RS. Therapeutic standards in Alzheimer disease. Alzheimer Dis Assoc Disord. 1999;13 Suppl 2:S20-6. PMID: 10622675.

2

Doody R, Whitehouse PJ, Chen Q, Wang L, Wu Q, Rosser M, et al. Alzheimer disease-related activities in China: a report from the International Working Group on the Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1998;12(4):263-5. PMID: 9876954.

41

Doody RS, Massman PJ, Mawad M, Nance M. Cognitive consequences of subcortical magnetic resonance imaging changes in Alzheimer's disease: comparison to small vessel ischemic vascular dementia. Neuropsychiatry Neuropsychol Behav Neurol. 1998;11(4):191-9. PMID: 9845410.

636

Rogers SL, Doody RS, Mohs RC, Friedhoff LT. Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group. Arch Intern Med. 1998;158(9):1021-31. PMID: 9588436.

1404

Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Neurology. 1998;50(1):136-45. PMID: 9443470.

2

Amaducci L, Baldereschi M, Doody R, Chandra V, Gaines AD. Cultural issues in the clinical diagnosis of Alzheimer disease. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:19-21. PMID: 9305509.

2

Antuono P, Doody R, Gilman S, Huff J, Scheltens P, Ueda K, et al. Diagnostic criteria for dementia in clinical trials. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:22-5. PMID: 9305510.

35

Clark CM, Ewbank D, Lerner A, Doody R, Henderson VW, Panisset M, et al. The relationship between extrapyramidal signs and cognitive performance in patients with Alzheimer's disease enrolled in the CERAD Study. Consortium to Establish a Registry for Alzheimer's Disease. Neurology. 1997;49(1):70-5. PMID: 9222172.

6

 

Doody RS. Treatment of Alzheimer's disease. Neurologist. 1997;3(6):333-43.

91

Perkins P, Annegers JF, Doody RS, Cooke N, Aday L, Vernon SW. Incidence and prevalence of dementia in a multiethnic cohort of municipal retirees. Neurology. 1997;49(1):44-50. PMID: 9222168.

79

Reisberg B, Schneider L, Doody R, Anand R, Feldman H, Haraguchi H, et al. Clinical global measures of dementia. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:8-18. PMID: 9305508.

23

Sabbagh MN, Lynn P, Jhingran S, Massman P, Villanueva-Meyer J, Olup J, et al. Correlations between SPECT regional cerebral blood flow and psychometric testing in patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1997;9(1):68-74. PMID: 9017531.

519

Schneider LS, Olin JT, Doody RS, Clark CM, Morris JC, Reisberg B, et al. Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord. 1997;11 Suppl 2:S22-32. PMID: 9236949.

29

Strite D, Massman PJ, Cooke N, Doody RS. Neuropsychological asymmetry in Alzheimer's disease: Verbal versus visuoconstructional deficits across stages of dementia. J Int Neuropsychol Soc. 1997;3(5):420-7. PMID: 9322400.

34

Thal LJ, Carta A, Doody R, Leber P, Mohs R, Schneider L, et al. Prevention protocols for Alzheimer disease. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:46-9. PMID: 9305516.

0     

 

Kataki M, Winikates J, Kirkpatrick J, Doody RS. Longitudinal study of aphasia in Creutzfeldt-Jakob disease. Neuropsychiatry Neuropsychol Behav Neurol. 1996;9(4):284-7.

20

Massman PJ, Doody RS. Hemispheric asymmetry in Alzheimer's disease is apparent in motor functioning. J Clin Exp Neuropsychol. 1996;18(1):110-21. PMID: 8926290.

66

Massman PJ, Kreiter KT, Jankovic J, Doody RS. Neuropsychological functioning in cortical-basal ganglionic degeneration: Differentiation from Alzheimer's disease. Neurology. 1996;46(3):720-6. PMID: 8618672.

41

Olin JT, Schneider LS, Doody RS, Clark CM, Ferris SH, Morris JC, et al. Clinical evaluation of global change in Alzheimer's disease: identifying consensus. J Geriatr Psychiatry Neurol. 1996;9(4):176-80. PMID: 8970010.

63

Doody RS, Massman P, Mahurin R, Law S. Positive and negative neuropsychiatric features in Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1995;7(1):54-60. PMID: 7711492.

62

Kotrla KJ, Chacko RC, Harper RG, Doody R. Clinical variables associated with psychosis in Alzheimer's disease. Am J Psychiatry. 1995;152(9):1377-9. PMID: 7653698.

107

Kotrla KJ, Chacko RC, Harper RG, Jhingran S, Doody R. SPECT findings on psychosis in Alzheimer's disease. Am J Psychiatry. 1995;152(10):1470-5. PMID: 7573586.

21

 

Shaibani A, Sabbagh M, Doody RS. Laughter and crying in neurologic disorders. Neuropsychiatry Neuropsychol Behav Neurol. 1994;7(4):243-50.

7

Doody RS. A reappraisal of localization theory with reference to aphasia. Part 1: Historical considerations. Brain Lang. 1993;44(3):296-326. PMID: 8513406.

2

Doody RS. A reappraisal of localization theory with reference to aphasia. Part 2: Language theories from outside neurology. Brain Lang. 1993;44(3):327-48. PMID: 8513407.

610

Davis KL, Thal LJ, Gamzu ER, Davis CS, Woolson RF, Gracon SI, et al. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group. N Engl J Med. 1992;327(18):1253-9. PMID: 1406817.

8

Doody RS, Hrachovy RA, Feher EP. Recurrent fluent aphasia associated with a seizure focus. Brain Lang. 1992;42(4):419-30. PMID: 1611466.

126

Doody RS, Jankovic J. The alien hand and related signs. J Neurol Neurosurg Psychiatry. 1992;55(9):806-10. PMID: 1402972.

0     

 

Doody RS. Sense and non-sense: Dissemination and empiricism in practice. Ethos. 1992;20(2):220-9.

147

Feher EP, Mahurin RK, Doody RS, Cooke N, Sims J, Pirozzolo FJ. Establishing the limits of the Mini-Mental State. Examination of 'subtests'. Arch Neurol. 1992;49(1):87-92. PMID: 1728269.

0     

 

Doody RS. Aphasia as postmodern (anthropological) discourse. J Anthropol Res. 1991;47(3):285-303.

4

Feher EP, Doody RS, Whitehead J, Pirozzolo FJ. Progressive nonfluent aphasia with dementia: A case report. J Geriatr Psychiatry Neurol. 1991;4(4):236-40. PMID: 1789913.

2

Doody RS, Rosenfield DB. Spasmodic dysphonia associated with palatal myoclonus. Ear Nose Throat J. 1990;69(12):829-32. PMID: 2079007.

2

Feher EP, Doody R, Pirozzolo FJ, Appel SH. Mental status assessment of insight and judgment. Clin Geriatr Med. 1989;5(3):477-98. PMID: 2680029.

155

Ornish D, Scherwitz LW, Doody RS, Kesten D, McLanahan SM, Brown SE, et al. Effects of stress management training and dietary changes in treating ischemic heart disease. Jama. 1983;249(1):54-9. PMID: 6336794.

3

Doody RS, Grose NP. The family medical history: Assessing patient understanding of diabetes mellitus. Diabetes Care. 1981;4(2):285-8. PMID: 7215084.

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