Pharmacogenetics of Epilepsy Laboratory

Journal articles authored and co-authored by members of the Pharmacogenetics of Epilepsy Laboratory are listed here in reverse chronological order and grouped by published year. Click on the Expand plus symbol or Collapse minus symbol symbol to expand/collapse the list of journal publications by year, respectively.

Click on the PubMed link for details of that publication.

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2024

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Journal Articles Published in 2024 (n = 3)

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PubMed

Reference

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Abreo TJ, Thompson EC, Madabushi A, Soh H, Varghese N, Vanoye CG, et al. Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. bioRxiv. 2024;:. PMID: 38260608.

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Bottom-Tanzer S, Corella S, Meyer J, Sommer M, Bolanos L, Murphy T, et al. Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model. Cereb Cortex. 2024;34(2):. PMID: 38365273.

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Nguyen T, Xiao E, Clark A, Shamim A, Maheshwari A. Screening for ADHD in adult patients with epilepsy: Prevalence of symptoms and challenges to diagnosis. J Atten Disord. 2024;28(1):51-7. PMID: 37694675.

2023

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Journal Articles Published in 2023 (n = 4)

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PubMed

Reference

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Curry RN, Aiba I, Meyer J, Lozzi B, Ko Y, McDonald MF, et al. Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation. Neuron. 2023;111(5):682-95 e9. PMID: 36787748.

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Krishnan V, Wu J, Mazumder AG, Kamen JL, Schirmer C, Adhyapak N, et al. Clinicopathologic dissociation: Robust Lafora body accumulation in Malin KO mice without observable changes in home-cage behavior. bioRxiv. 2023;:. PMID: 37745312.

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Metzger BA, Kalva P, Mocchi MM, Cui B, Adkinson JA, Wang Z, et al. Intracranial stimulation and EEG feature analysis reveal affective salience network specialization. Brain. 2023;146(10):4366-77. PMID: 37293814.

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Varghese N, Moscoso B, Chavez A, Springer K, Ortiz E, Soh H, et al. KCNQ2/3 gain-of-function variants and cell excitability: Differential effects in CA1 versus L2/3 pyramidal neurons. J Neurosci. 2023;43(38):6479-94. PMID: 37607817.

2022

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Journal Articles Published in 2022 (n = 5)

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PubMed

Reference

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Jaramillo MA, Pham T, Kamrudin S, Khanna R, Maheshwari A. Seizure exacerbation with anti-seizure medications in adult patients with epilepsy. Epilepsy Res. 2022;181:106885. PMID: 35202904.

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Jing J, Dunbar C, Sonesra A, Chavez A, Park S, Yang R, et al. Removal of KCNQ2 from parvalbumin-expressing interneurons improves anti-seizure efficacy of retigabine. Exp Neurol. 2022;355:114141. PMID: 35691372.

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Mazzaferro S, Msekela DJ, Cooper EC, Maheshwari A, Sine SM. Genetic variant in nicotinic receptor alpha4-subunit causes sleep-related hyperkinetic epilepsy via increased channel opening. Int J Mol Sci. 2022;23(20):. PMID: 36292983.

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Nascimento FA, Jing J, Strowd R, Sheikh IS, Weber D, Gavvala JR, et al. Competency-based EEG education: A list of "must-know" EEG findings for adult and child neurology residents. Epileptic Disord. 2022;24(5):1-4. PMID: 35904042.

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Pham C, Roy C, Tang C, Maheshwari A. Low recognition of attention deficit hyperactivity disorder in adult patients admitted to the Epilepsy Monitoring Unit. Brain Behav. 2022;:e32731. PMID: 35899366.

<2021

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Journal Articles Published in <2021 (n = 33)

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PubMed

Reference

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Dunbar C, Lee M, Maheshwari A. High yield of screening for ADHD in the epilepsy monitoring unit. J Atten Disord. 2021;25(8):1120-8. PMID: 31707913.

0     

Esopenko C, Meyer J, Wilde EA, Marshall AD, Tate DF, Lin AP, et al. A global collaboration to study intimate partner violence-related head trauma: The ENIGMA consortium IPV working group. Brain Imaging Behav. 2021;15(2):475-503. PMID: 33405096.

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Nascimento FA, Chu J, Fussner S, Krishnan V, Maheshwari A, Gavvala JR. Neurostimulation EEG artifacts: VNS, RNS, and DBS. Arq Neuropsiquiatr. 2021;79(8):752-3. PMID: 34133495.

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Chourasia N, Maheshwari A, Kalamangalam G. Cognitive and functional status in late-onset Lennox-Gastaut syndrome: Variation on a classic phenotype. Epilepsy Behav. 2020;102:106660. PMID: 31770718.

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Hatcher A, Yu K, Meyer J, Aiba I, Deneen B, Noebels JL. Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model. J Clin Invest. 2020;130(5):2286-300. PMID: 32250339.

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Karas PJ, Giridharan N, Treiber JM, Prablek MA, Khan AB, Shofty B, et al. Accuracy and workflow improvements for responsive neurostimulation hippocampal depth electrode placement using robotic stereotaxy. Front Neurol. 2020;11:590825. PMID: 33424745.

0     

Maheshwari A. Rodent EEG: Expanding the Spectrum of Analysis. Epilepsy Curr. 2020;20(3):149-53. PMID: 32354231.

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Nascimento FA, Maheshwari A, Chu J, Gavvala JR. EEG education in neurology residency: Background knowledge and focal challenges. Epileptic Disord. 2020;22(6):769-74. PMID: 33399093.

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Vittala A, Murphy N, Maheshwari A, Krishnan V. Understanding cortical dysfunction in schizophrenia with TMS/EEG. Front Neurosci. 2020;14:554. PMID: 32547362.

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Marafi D, Fussner S, Chen YY, Yoshor D, Van Ness P, Maheshwari A. Picking up the pace. Clin Neurophysiol. 2019;130(9):1528-30. PMID: 31295722.

3

Palagina G, Meyer JF, Smirnakis SM. Inhibitory units: An organizing nidus for feature-selective sub-networks in area V1. J Neurosci. 2019;39(25):4931-44. PMID: 30979814.

12

Meyer J, Maheshwari A, Noebels J, Smirnakis S. Asynchronous suppression of visual cortex during absence seizures in stargazer mice. Nat Commun. 2018;9(1):1938. PMID: 29769525.

2

Meyer JF, Golshani P, Smirnakis SM. The effect of single pyramidal neuron firing within layer 2/3 and layer 4 in mouse V1. Front Neural Circuits. 2018;12:29. PMID: 29713266.

20

Soh H, Park S, Ryan K, Springer K, Maheshwari A, Tzingounis AV. Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission. elife. 2018;7:. PMID: 30382937.

11

Lee S, Meyer JF, Park J, Smirnakis SM. Visually Driven Neuropil Activity and Information Encoding in Mouse Primary Visual Cortex. Front Neural Circuits. 2017;11:50. PMID: 28785207.

27

Lopez AY, Wang X, Xu M, Maheshwari A, Curry D, Lam S, et al. Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder. Mol Psychiatry. 2017;22(10):1464-72. PMID: 27956739.

6

Maheshwari A, Akbar A, Wang M, Marks RL, Yu K, Park S, et al. Persistent aberrant cortical phase-amplitude coupling following seizure treatment in absence epilepsy models. J Physiol. 2017;595(23):7249-60. PMID: 28901011.

23

Palagina G, Meyer JF, Smirnakis SM. Complex visual motion representation in mouse area V1. J Neurosci. 2017;37(1):164-83. PMID: 28053039.

12

Pohlen MS, Jin J, Tobias RS, Maheshwari A. Pharmacoresistance with newer anti-epileptic drugs in mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsy Res. 2017;137:56-60. PMID: 28941835.

17

Maheshwari A, Marks RL, Yu KM, Noebels JL. Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy. Epilepsia. 2016;57(1):79-88. PMID: 26663261.

4

Lillis KP, Dulla C, Maheshwari A, Coulter D, Mody I, Heinemann U, et al. WONOEP appraisal: Molecular and cellular imaging in epilepsy. Epilepsia. 2015;56(4):505-13. PMID: 25779014.

22

Maheshwari A, Fischer M, Gambetti P, Parker A, Ram A, Soto C, et al. Recent US case of variant Creutzfeldt-Jakob disease - global implications. Emerg Infect Dis. 2015;21(5):750-9. PMID: 25897712.

49

Chen DK, Maheshwari A, Franks R, Trolley GC, Robinson JS, Hrachovy RA. Brief group psychoeducation for psychogenic nonepileptic seizures: A neurologist-initiated program in an epilepsy center. Epilepsia. 2014;55(1):156-66. PMID: 24446955.

0     

Hannawi Y, Satpute SS, Maheshwari A. Mystery case: Eyelid myoclonia with absences in an adult patient. Neurology. 2014;82(8):e63-4. PMID: 24566229.

40

Maheshwari A, Noebels JL. Monogenic models of absence epilepsy: Windows into the complex balance between inhibition and excitation in thalamocortical microcircuits. Prog Brain Res. 2014;213:223-52. PMID: 25194492.

39

Olivetti PR, Maheshwari A, Noebels JL. Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome. Sci Transl Med. 2014;6(220):220ra12. PMID: 24452264.

28

Maheshwari A, Nahm WK, Noebels JL. Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice. Front Cell Neurosci. 2013;7:156. PMID: 24065886.

119

Kramer MA, Truccolo W, Eden UT, Lepage KQ, Hochberg LR, Eskandar EN, et al. Human seizures self-terminate across spatial scales via a critical transition. Proc Natl Acad Sci U S A. 2012;109(51):21116-21. PMID: 23213262.

6

Wray SH, Martinez-Hernandez E, Dalmau J, Maheshwari A, Chen A, King S, et al. Paraneoplastic upbeat nystagmus. Neurology. 2011;77(7):691-3. PMID: 21813784.

19

Meyer JF, Wolf B, Gross GW. Magnetic stimulation and depression of mammalian networks in primary neuronal cell cultures. IEEE Trans Biomed Eng. 2009;56(5):1512-23. PMID: 19203881.

95

Wuthrich C, Dang X, Westmoreland S, McKay J, Maheshwari A, Anderson MP, et al. Fulminant JC virus encephalopathy with productive infection of cortical pyramidal neurons. Ann Neurol. 2009;65(6):742-8. PMID: 19557867.

0     

 

Ilchmann F, Lob V, Meyer J, Ressler H, Wankerl B, Wiest J, et al. Automated cell analytics, application on sensor chips. Screening-Trends in Drug Discovery. 2008;9:21-3.

0     

Swint-Kruse L, Zhan H, Fairbanks BM, Maheshwari A, Matthews KS. Perturbation from a distance: Mutations that alter LacI function through long-range effects. Biochemistry. 2003;42(47):14004-16. PMID: 14636069.