Integrative Functional Genomics Laboratory

Click on the Expand plus sign sign to list the poster and platform presentations by year. Then click on the link to view that presentation.

2024

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    AD/PD
    2024 International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders in Lisbon, Portugal (March 5-9, 2024)
    • Dissecting oligogenic mechanisms of lysosomal susceptibility in Parkinson's disease.

      Zhao J, Gu M, Yu M, Barros De Paula R, Bellen H, Shulman J

2023

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    American Academy of Neurology (AAN)
    75th Annual Meeting in Boston, Mass. (April 22-28, 2023)
    • Precision neurology for dementia.

      Shulman J, Vanegas-Arroyave N, Fong J, Elsea S, Lin C, Saade H, et al.

2022

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    2022 Alzheimer's Association International Conference (AAIC)
    San Diego, Calif. (July 30 - Aug. 4, 2022)
    • "Hablemos de Alzheimer": Words Mexican Americans use to talk about Alzheimer's disease genetic testing. Implications for precision medicine education.

      Fong JC, Chavez F, Silos K, Castro GC, Arroyo-Miranda ML, Kunik ME, et al.

    • A matrisomal proteomics network modulates tau and amyloid-beta toxicity in fly AD models.

      Li-Kroeger D, Al-Ramahi I, Marella A, Amoh BK, Smith N, Botas J, et al.

    • Cell-specific responses to Tau pathology in the aging brain.

      Wu T, Guo C, Deger JM, Dhindsa J, Al-Ouran R, Shulman JM

    • Retromer subunit, VPS29, regulates vacuolar-type ATPase and lysosomal acidification in the aging brain.

      Ye H, Bagchi P, Wu T; Dammer EB, Seyfried NT, Shulman JM

<2021

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    Society for Neuroscience (SFN)
    Virtual Annual Meeting (Nov. 8-11, 2021)
    • Functional validation of the cytoskeletal protein Plectin in Alzheimer's disease.

      Lee TV, Allison K, Seyfried NT, Levey AI, Shulman JM

    • Alzheimer's disease risk gene CD2AP modulates synaptic structure and plasticity.

      Paveskovic M, Ojelade S, Pekarek B, Kochukov M, Arenkiel B, Shulman J

    2021 Alzheimer's Association International Conference (AAIC)
    Virtual Meeting (July 26-30, 2021)
    • Integrating multimodal data to support Alzheimer's disease target prioritization.

      Cary GA, Gockley J, Lehallier B, Leal K, Greenwood AK, Shulman JM, et al.

    • The Alzheimer's disease risk gene CD2AP modulates mammalian synaptic structure and plasticity.

      Paveskovic M, Ojelade SA, Kochukov M, Pekarek B, Arenkiel B, Shulman JM

    • Elucidiating cellular contributions to tau-mediated neurodegeneration using Drosophila and single cell transcriptomics.

      Wu T, Guo C, Shulman JM

    2020 Alzheimer's Association International Conference (AAIC)
    Virtual Meeting (July 27-31, 2020)
    • A consensus proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.

      Johnson ECB, Dammer EB, Duong D, Ping L, Zhou M, Yin L, et al.

    American Academy of Neurology (AAN)
    72nd Annual Meeting in Toronto, Ontario, Canada (April 25 - May 1, 2020)
    • Addressing challenges of clinical comprehensive genetic testing in Parkinson's disease.

      Hill E, Deger J, Robak L, Rao S, Saade H, Ripperger B, et al.

    Society for Neuroscience (SFN)
    49th Annual Meeting in Chicago, Ill. (Oct. 19-23, 2019)
    • Investigating the role of CD2AP, an Alzheimer's disease susceptibility gene, in mammalian synaptic structure and function.

      Paveskovic M, Ojelade SA, Pekarek BT, Arenkiel BR, Shulman JM

    American Neurological Association (ANA)
    144th Annual Meeting in St. Louis, Mo. (Oct. 13-15, 2019)
    • A consensus Alzheimer's disease brain protein co-expression network identifies robust biological alterations associated with early- and late-stage disease.

      Johnson ECB, Dammer EB, Duong DM, Yin L, Betarbet R, Shulman JM, et al.

    • Biological alterations associated with early- and late-stage disease.

      Johnson ECB, Dammer EB, Duong DM, Yin L, Betarbet R, Shulman JM, et al.

    • Parkinson's disease susceptibility in carriers of lysosomal storage disorder genes.

      Robak L, Shulman J

    2019 Alzheimer's Association International Conference (AAIC)
    Los Angeles, Calif. (July 14-18, 2019)
    • Tau-mediated disruption of the spliceosome triggers cryptic RNA splicing and neurodegeneration in Alzheimer's disease.

      Guo C, Hsieh Y-C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, et al.

    • Functional dissection of an Alzheimer's disease susceptibility gene network.

      Lee TV, Allison KS, Ojelade SA, Lah JJ, Levey AI, Seyfried NT, et al.

    • Functional dissection of Alzheimer's disease brain gene expression signatures in humans and mouse models.

      Mangleburg CG, Wan Y-W, Al-Ouran R, Lee TV, Allison KS, Logsdon BA, et al.

    American Academy of Neurology (AAN)
    71st Annual Meeting in Philadelphia, Penn. (May 4-10, 2019)
    • Genome-wide association study meta-analysis for Parkinson disease motor subtypes.
      [Platform Presentation]

      Alfradique-Dunham I, Blauwendraat C, Al-Ouran R, von Coelln R, Tan M, Hill EJ, et al.

    • Capturing Parkinson's disease heterogeneity with quantitative mobility measures.
      [Platform Presentation]

      Hill EJ, Alfradique-Dunham I, Mangleburg CG, Ripperger B, Stillwell A, Rao S, et al.

    Society for Neuroscience (SFN)
    48th Annual Meeting in San Diego, Calif. (Nov. 3-7, 2018)
    • Sex specific Alzheimer's disease heterogeneity identified through cross study integrative analysis of RNA-seq data from the AMP-AD consortium.

      Logsdon B, Perumal TM, Swarup V, Funk C, Allen M, Wang M, et al.

    • cindr, the Drosophila homolog of CD2AP, plays a conserved role in synapse function and protein turnover.

      Ojelade SA, Lee TV, Giagtzoglou N, Shulman J

    • A druggable genome screen identifies modifiers of α-synuclein levels via a tiered cross-species validation approach.

      Vazquez-Velez G, Rousseaux MW, Al-Ramahi I, Jeong H-H, Bajic AS, Revelli J-P, et al.

    Movement Disorder Society (MDS)
    22nd International Congress of Parkinson's Disease and Movement Disorders in Hong Kong, China (Oct. 5-9, 2018)
    • Integrated whole exome sequencing and chromosomal microarray in familial Parkinson's disease.

      Robak L, Du R, Yuan B, Gu S, Akdemir Z, Jankovic J, et al.

    • Quantitative mobility metrics from a body-fixed sensor predict incident parkinsonism in older adults.

      von Coelln R, Dawe R, Shulman J, Yu L, Leurgans S, Hausdorff J, et al.

    • Loss of VPS29 disrupts retromer function and synaptic transmission, leading to neurodegeneration in Drosophila.

      Ye H, Li-Kroeger D, Li Y, Bellen H, Shulman J

    2018 Alzheimer's Association International Conference (AAIC)
    Chicago, Ill. (July 22-26, 2018)
    • Cindr, the Drosophila homolog of CD2AP, affects synapse function and protein turnover.

      Ojelade SA, Lee TV, Giagtzoglou N, Shulman JM

    American Academy of Neurology (AAN)
    70th Annual Meeting in Los Angeles, Calif. (April 21-27, 2018)
    • Whole exome sequencing in essential tremor.

      Alfradique-Dunham I, Robak L, Kaw A, Fagbongbe OI, Akdemir ZC, Young E, et al.

    • Integrated whole exome sequencing and chromosomal microarray in familial Parkinson's disease.

      Robak L, Du R, Yuan B, Gu S, Akdemir ZC, Tejomurtula A, et al.

    Society for Neuroscience (SFN)
    47th Annual Meeting in Washington, DC (Nov. 11-15, 2017)
    • Systems biology resource for Alzheimer's disease target prioritization: The AMP-AD Knowledge Portal.

      Daily K, Logsdon B, Peters M, Al-Ouran R, Wan YW, Shulman JM, et al.

    • Tau-mediated disruption of the spliceosome in Alzheimer's disease models.

      Hsieh Y-C, Guo C, Yalamanchili HK, Li Y, Lasagna-Reeves CA, Xu Y, et al.

    Movement Disorder Society (MDS)
    21st International Congress of Parkinson's Disease and Movement Disorders in Vancouver, BC, Canada (June 4-8, 2017)
    American Academy of Neurology (AAN)
    69th Annual Meeting in Boston, Mass. (April 22-28, 2017)
    Society of General Internal Medicine (SGIM)
    2017 Southern Regional Meeting in New Orleans, La. (Feb. 10-12, 2017)
    • Ataxia: The first sign of breast cancer.

      Rizk CB, Savitt DJ, Yu M, Kung D

    American Academy of Neurology (AAN)
    68th Annual Meeting in Vancouver, BC, Canada (April 15-21, 2016)
    • A case of neurosarcoidosis masquerading as subacute inflammatory demylelinating polyneuropathy.

      Rizk C, Savitt D, Jain S, Kass J

    American Academy of Pediatrics (AAP)
    2015 National Conference and Exhibition in Washington, DC (Oct. 23-27, 2015)
    • Teaching mental health in middle schools: Two initiatives targeting students in two urban middle schools.

      Hernandez S, Billups D, Michael S, Peicher V, Rizk CB, Idicula S

    Society for Pediatric Pathology (SPP)
    Fall Meeting in Toronto, Ontario, Canada (Oct. 1-4, 2015)
    • Rare placental tumor: A report of two mesenchymomas.

      Shinnick JK, Lou LH, Ilse A, Rizk CB, Shahid R, Thomson L, et al.

    Movement Disorder Society (MDS)
    19th International Congress of Parkinson's Disease and Movement Disorders in San Diego, Calif. (June 14-18, 2015)
    • Dystonia-spasticity in a patient with a novel SLC25A12 mutation.

      Parnes M, Robak L, Shulman JM, Stocco A, Jankovic J

    American Academy of Neurology (AAN)
    67th Annual Meeting in Washington, DC (April 18-25, 2015)
    American Academy of Neurology (AAN)
    65th Annual Meeting in San Diego, Calif. (March 16-23, 2013)
    • Exploring the impact of Parkinson disease (PD) susceptibility genes in elders without PD.
      [Platform Presentation]

      Shulman J, Yu L, Buchman A, Evans D, Schneider J, Bennett D, et al.

    American Neurological Association (ANA)
    137th Annual Meeting in Boston, Mass. (Oct. 7-9, 2012)
    • Genetic susceptibility for amyloid pathology in Alzheimer's disease.

      Shulman JM, Chen K, Keenan BT, Chibnik LB, Thiyyagura P, McCabe C, et al.

    • Integrating human and fly genetics to understand Alzheimer's disease susceptibility.

      Shulman JM, Imboywa S, Diamond AE, Chipendo P, De Jager PL, Feany MB

    Parkinson Study Group (PSG)
    26th Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson Disease and Other Movement Disorders in Irving, Texas (May 11, 2012)
    • Genetic analyses of Parkinson's disease endophenotypes.
      [Platform Presentation]

      Shulman JM

    American Neurological Association (ANA)
    136th Annual Meeting in San Diego, Calif. (Sept. 25-27, 2011)
    • Integrating genome-wide association and functional validation to understand susceptibility for Alzheimer's pathology.
      [Platform Presentation]

      Shulman JM, Chipendo PI, Chibnik LB, Keenan BT, Tran D, Huentelman MA, et al.

    Michael J. Fox Parkinson's Research Foundation
    Genetic Epidemiology of Parkinson's Disease Consortium Meeting in Evanston, Ill. (Sept. 18-21, 2011)
    • What can endophenotypes teach us about Parkinson's disease?
      [Oral Presentation]

      Shulman JM

    2011 International Conference on Alzheimer's Disease (ICAD)
    Paris, France (July 16-21, 2011)
    • A candidate causal variant in the CR1 locus.

      Keenan B, Shulman J, Chibnik L, Corneveaux J, Allen A, Myers A, et al.

    • Alzheimer's disease susceptibility loci: Evidence for natural selection and altered gene expression.

      Raj T, Shulman J, Chibnik L, Keenan B, Stranger B, Evans D, et al.

    • Genetic factors associated with the rate of cognitive decline in Alzheimer's disease.

      Sherva R, Tripodis Y, Shulman J, Chibnik L, Crane P, Bennett D, et al.

    • A genome-wide association scan for episodic memory decline in aging.

      Shulman J, Chibnik L, Keenan B, Destefano A, Leurgans S, Wilson R, et al.

    • Integrating genome-wide association and functional validation to understand susceptibility for Alzheimer's pathology.
      [Platform Presentation]

      Shulman J, Chipendo P, Chibnik L, Keenan B, Tran D, Aubin C, et al.

    American Academy of Neurology (AAN)
    63rd Annual Meeting in Honolulu, Hawaii (April 9-16, 2011)
    • A genome-wide association scan for episodic memory decline in aging.
      [Platform Presentation]

      Shulman JM, Chibnik LB, Leurgans SE, Wilson RS, Tran D, Keenan BT, et al.

    • Functional fine mapping of the CR1 locus identifies a causal variant for Alzheimer's disease susceptibility.
      [Platform Presentation]

      Shulman JM, Keenan BT, Chibnik LB, Raj T, Tran D, Aubin C, et al.

    Keystone Symposium
    Symposium on Neurodegenerative Diseases in Taos, N.M. (Feb. 21-26, 2011)
    • Enhancing power for gene discovery in Alzheimer's disease: Intermediate phenotypes and functional validation in drosophila.
      [Platform Presentation]

      Shulman JM

    Rush University
    ROS/MAP Investigator Meeting in Chicago, Ill. (2011)
    • Genomics of cognitive decline and neuropathology.
      [Oral Presentation]

      Shulman JM

    American Society of Human Genetics (ASHG)
    60th Annual Meeting in Washington, DC (Nov. 2-6, 2010)
    • Enhancing power for gene discovery in Alzheimer's disease: Intermediate phenotypes and functional validation in drosophila.
      [Platform Presentation]

      Shulman JM, Chipendo1 P, Aubin C, Kramer P, Schneider JA, Bennett DA, et al.

    American Academy of Neurology (AAN)
    62nd Annual Meeting in Toronto, Canada (April 10-17, 2010)
    • Relation of the Alzheimer's disease susceptibility allele at the CR1 locus to cognitive decline and Alzheimer's disease neuropathology in older persons.
      [Platform Presentation]

      De Jager P, Chibnik L, Aggarwal N, Shulman J, Schneider J, Evans D, et al.

    • Enhancing power for gene discovery in Alzheimer's disease: Intermediate phenotypes and functional validation in drosophila.
      [Platform Presentation]

      Shulman JM, Aubin C, Tran D, Kramer P, Feany MB, Bennett D, et al.

    • Alzheimer's disease risk alleles in PCDH11X and SORL1 are associated with the rate of cognitive decline in subjects with multiple sclerosis.
      [Platform Presentation]

      Xia Z, Chibnik LB, Shulman JM, Aubin C, Tran D, Glanz BI, et al.

    Rush University
    CHAP Investigator Meeting in Chicago, Ill. (2010)
    • Genome-wide association scans for cognitive decline.
      [Oral Presentation]

      Shulman JM

    Genetics Society of America (GSA)
    41st Annual Drosophila Research Conference in Pittsburgh, Penn. (March 22-26, 2000)
    • A role for PAR-1 in oocyte determination.
      [Platform Presentation]

      Shulman JM

    British Society for Developmental Biology (BSDB)
    BSCB/BSDB Joint Spring Meeting in Manchester, England (April 13-16, 1999)
    • A drosophila homologue of c. elegans PAR-1.
      [Platform Presentation]

      Shulman JM

    Genetics Society of America (GSA)
    40th Annual Drosophila Research Conference in Bellevue, Wash. (March 24-28, 1999)
    • A drosophila homologue of c. elegans PAR-1.
      [Platform Presentation]

      Shulman JM

    Genetics Society of America (GSA)
    39th Annual Drosophila Research Conference in Washington, DC (March 25-29, 1998)
    • Subcellular relocalization of dishevelled mediates polarity signaling.
      [Platform Presentation]

      Shulman JM

    Genetics Society of America (GSA)
    37th Annual Drosophila Research Conference in San Diego, Calif. (April 27 - May 1, 1996)
    • Dishevelled is a multifunctional signal transducer.
      [Platform Presentation]

      Shulman JM