Neurology: Case of the Month

All of the following are considered to be one of the multi-system atrophies EXCEPT:

The multi-system atrophies are most strongly associated with which of the following pathological inclusion bodies?

[ A ] An intracytoplasmic, eosinophilic neuronal inclusion with a surrounding halo
[ B ] An intracytoplasmic, eosinophilic oligodendroglial inclusion
[ C ] An intranuclear, eosinophilic neuronal inclusion
[ D ] An argyrophilic, intracytoplasmic neuronal inclusion
[ E ] An argyrophilic, intranuclear neuronal inclusion

All of the following are true statements regarding the multi-system atrophies EXCEPT:

[ A ] In Shy-Drager syndrome, the predominant features are parkinsonism and dysautonamia.
[ B ] In patients with parkinsonism, dysautonomia is diagnostic of Shy-Drager syndrome.
[ C ] Patients with OPCA may demonstrate gaze impairment, pyramidal dysfunction, and axial rigidity.
[ D ] Striatonigral degeneration is occasionally associated with cervical dystonias.
[ E ] Pyramidal signs are fairly common in patients with multi-system atrophy.

All of the following signs/symptoms may be found in patients with one of the multi-system atophies EXCEPT:

All of the following statements are TRUE regarding the multi-system atrophies EXCEPT:

[ A ] Patients with these conditions tend to respond poorly to DOPA replacement, in part, because the defect lies in loss of the dopamine receptor.
[ B ] Parkinsonism is found in most, if not all, cases of multi-system atrophy.
[ C ] Autonomic symptoms occur commonly in patients with MSA.
[ D ] Lewy bodies are the pathologic hallmark of this disease.
[ E ] Most cases of MSA present in a symmetrical fashion in contradistinction to Cortico-basal ganglionic degeneration.

Test Yourself — Patient 22