Zhandong Liu, Ph.D.
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Zhandong Liu, Ph.D.
Associate Professor
Positions
- Associate Professor
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Pediatrics
Neurology
Baylor College of Medicine
Houston, Texas United States
- Chief of Computational Sciences
-
Pediatrics
Texas Children's Hospital
Houston, Texas United States
- Co-Director/Curriculum Chair
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Quantitative & Computational Biosciences Graduate Program
Baylor College of Medicine
Houston, Texas United States
- Member
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Genetics & Genomics Graduate Program
Baylor College of Medicine
Houston, Texas United States
Addresses
- Duncan Neurological Research Institute (Office)
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Room: NRI-1365.08
Houston, TX 77030
United States
Education
- Ph.D. from University Of Pennsylvania
- 01/2010 - Philadelphia, PA United States
- M.S. from Wayne State University
- 01/2003 - Detroit, MI United States
- B.S. from Nankai University
- 05/2001 - Tianjin, - China
Honors & Awards
- Outstanding Service Award
- The International Association for Intelligent Biology and Medicine (06/2018)
Professional Interests
- Bioinformatics, Big Data analysis, Machine Learning
- Genomics and Genetics
- Virtual and Augmented Reality
Professional Statement
My research interests include topics in genomics, transcription regulation, disease genes prioritization, and machine learning. I often examine problems in these areas using methods and models from computer science, statistics and related disciplines. Recently, I have been working on using Generalized Graphical models and Augmented Reality techniques to integrate multiple data types in the interest of advancing our understanding of neurological diseases.Websites
Selected Publications
- A. Raman, A. E. Pohodich, Y.-W. Wan, H. Yalamanchili, B. Lowry, H. Zoghbi, and Z. Liu "Apparent bias towards long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations." Nature Communications. 2018; Pubmed PMID: 30104565
- H. Yi, A. T. Raman, H. Zhang, G. I. Allen, Z. Liu "Detecting hidden batch factors through data-adaptive adjustment for biological effects." Bioinformatics. 2018; Pubmed PMID: 29617963
- H.-H. Jeong, S.-Y. Kim, M. W. Rousseaux, H. Y. Zoghbi, and Z. Liu "CRISPRcloud: A secure cloud-based pipeline for CRISPR pooled screen deconvolution." Bioinformatics. 2017; Pubmed PMID: 28541456
- J. Wang, R. Al-Ouran, Y. Hu, S.-Y. Kim, Y.-W. Wan, M. F. Wangler, S. Yamamoto, H.-T. Chao, A. Comjean, S. E. Mohr, UDN, N. Perrimon, Z. Liu*, and H. J. Bellen* "MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome." Am. J. Hum. Genet. 2017 Jun;100(6):843-853. Pubmed PMID: 28502612
- Zhong Y, Liu Z "Gene expression deconvolution in linear space.." Nat. Methods. 2011;9(1):41495. Pubmed PMID: 22205510
Memberships
- International Society of Computational Biology
- Member (01/2010)
- International Journal of Computational Biology and Drug Design
- Managing Editor (07/2012 - 06/2014)
Funding
- Functional Dissection of Alzheimer's Diseases Networks in Drosophila: from Association to Causal Modulators of Age-Dependent Neurodegeneration - #1R01AG057339
- $3,399,125.00 (09/01/2017 - 05/31/2022) Grant funding from NIH
- Development and Validation of a Network-Guided, Multi-Objective Optimization Model for Cancer Data Analysis - #RP170387
- $889,679.00 (12/01/2016 - 11/30/2019) Grant funding from CPRIT
- PFI-TT: Creation of an augmented-reality platform for treatment of phobias/anxiety in children with Autism Spectrum Disorder
- $199,977.00 (09/01/2018 - 08/30/2020) Grant funding from NSF
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