Positions
- Professor
-
Medicine-Immunology, Allergy and Rheumatology
Baylor College of Medicine
Houston, TX US
- Fulbright Endowed Chair in Pathology
-
Pathology & Immunology and Medicine
Immunology, Allergy & Rheumatology
Baylor College of Medicine
Houston, Texas United States
- Core Faculty
-
Center for Translational Research on Inflammatory Diseases (CTRID)
Michael E. DeBakey VA Medical Center
Baylor College of Medicine
Houston, Texas United States
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Addresses
- Baylor St. Luke's Medical Center (Clinic)
-
7200 Cambridge, Suite 10B
Houston, TX 77030
United States
Phone: (713) 798-3390
Education
- Fellowship at University of California, San Francisco Affiliate Hospitals
- 06/1996 - San Francisco, CA United States
- Pulmonary and Critical Care Medicine
- MD from University of Texas Southwestern Medical School
- 05/1988 - Dallas, TX United States
- Internship at Duke University Medical Center
- 06/1989 - Durham, NC United States
- Residency at Duke University Medical Center
- 06/1991 - Durham, United States
Certifications
- Internal Medicine
- American Board of Internal Medicine
- Pulmonary Medicine
- American Board of Internal Medicine
- Critical Care Medicine
- American Board of Internal Medicine
Professional Interests
- Asthma
- T cells
- Airway physiology
- Proteases
- Fungi
- Alzheimer's Disease
Websites
Selected Publications
- Wu Y, Zeng Z, Guo Y, Song L, Weatherhead JE, Huang X, Zeng Y, Bimler L, Chang C, Knight JM, Valladolid C, Sun H, Cruz MA, Hube B, Naglik JR, Luong AU, Kheradmand F, Corry DB. "Candida Albicans Elicits Protective Allergic Responses Via Platelet Mediated T helper 2 and T helper 17 Cell Polarization.." Immunity. 2021;54(11):2595-2610. Pubmed PMID: 34506733
- Wu Y, Du S, Johnson JL, Tung H-Y, Landers CT, Liu, Y, Seman BG, Wheeler RT, Costa-Mattioli M, Kheradmand F, Zheng H, Corry DB. "Microglia and Amyloid Precursor Protein Coordinate Control of Transient Candida Cerebritis With Memory Deficits.." Nat Commun. 2019;10(1):58. Pubmed PMID: 30610193
- Lu W, You R, Yuan X, Yang T, Samuel ELG, Marcano DC, Sikkema WKA, Tour JM, Rodriguez A, Kheradmand F and Corry DB. "The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote TH17 cell–dependent emphysema.." Nat Immunol. 2015;18:1185-1194. Pubmed PMID: 26437241
- Millien VO, Lu W, Shaw J, Yuan X, Mak G, Roberts L, Song L-Z, Knight JM, Creighton CJ, Luong A, Kheradmand F, Corry DB. "Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4." Science. 2013;341:792-796. Pubmed PMID: 23950537
- Mak G, Porter PC, Bandi V, Kheradmand F, Corry DB "Tracheobronchial mycosis in a retrospective case-series study of five status asthmaticus patients.." Clin. Immunol.. 2013 Feb;146(2):77-83. Pubmed PMID: 23280490
- Porter PC, Ongeri V, Luong A, Kheradmand F, Corry DB "Seeking common pathophysiology in asthma, atopy and sinusitis.." Trends Immunol.. 2011 Feb;32(2):43-9. Pubmed PMID: 21239229
- Corry DB, Grünig G, Hadeiba H, Kurup VP, Warnock ML, Sheppard D, Rennick DM, Locksley RM "Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice.." Mol. Med.. 1998 May;4(5):344-55. Pubmed PMID: 9642684
- Grünig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, Sheppard D, Mohrs M, Donaldson DD, Locksley RM, Corry DB "Requirement for IL-13 independently of IL-4 in experimental asthma.." Science. 1998 Dec 18;282(5397):2261-3. Pubmed PMID: 9856950
- Greenlee KJ, Corry DB, Engler DA, Matsunami RK, Tessier P, Cook RG, Werb Z, Kheradmand F "Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation.." J. Immunol.. 2006 Nov 15;177(10):7312-21. Pubmed PMID: 17082650
- Porter PC, Yang T, Luong A, Delclos GL, Abramson SL, Kheradmand F, Corry DB "Proteinases as molecular adjuvants in allergic airway disease.." Biochim. Biophys. Acta. 2011 Nov;1810(11):1059-65. Pubmed PMID: 21712069
- Corry DB, Irvin CG "Promise and pitfalls in animal-based asthma research: building a better mousetrap.." Immunol. Res.. 2006;35(3):279-94. Pubmed PMID: 17172652
- Polikepahad S, Knight JM, Naghavi AO, Oplt T, Creighton CJ, Shaw C, Benham AL, Kim J, Soibam B, Harris RA, Coarfa C, Zariff A, Milosavljevic A, Batts LM, Kheradmand F, Gunaratne PH, Corry DB "Proinflammatory Role for let-7 MicroRNAS in Experimental Asthma.." J. Biol. Chem.. 2010 Sep 24;285(39):30139-49. Pubmed PMID: 20630862
- Polikepahad S, Corry DB "Profiling of T helper cell-derived small RNAs reveals unique antisense transcripts and differential association of miRNAs with argonaute proteins 1 and 2.." Nucleic Acids Res.. 2013 Jan 1;41(2):1164-77. Pubmed PMID: 23185045
- Corry DB, Kiss A, Song LZ, Song L, Xu J, Lee SH, Werb Z, Kheradmand F "Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines.." FASEB J.. 2004 Jun;18(9):995-7. Pubmed PMID: 15059974
- Yang T, Ramocki MB, Neul JL, Lu W, Roberts L, Knight J, Ward CS, Zoghbi HY, Kheradmand F, Corry DB "Overexpression of Methyl-CpG Binding Protein 2 Impairs TH1 Responses.." Sci Transl Med. 2012 Dec 5;4(163):163ra158. Pubmed PMID: 23220634
- Porter PC, Roberts L, Fields A, Knight M, Qian Y, Delclos GL, Han S, Kheradmand F, Corry DB "Necessary and sufficient role for T helper cells to prevent fungal dissemination in allergic lung disease.." Infect. Immun.. 2011 Nov;79(11):4459-71. Pubmed PMID: 21875960
- Tai W, Roberts L, Seryshev A, Gubatan JM, Bland CS, Zabriskie R, Kulkarni S, Soong L, Mbawuike I, Gilbert B, Kheradmand F, Corry DB "Multistrain influenza protection induced by a nanoparticulate mucosal immunotherapeutic.." Mucosal Immunol. 2011 Mar;4(2):197-207. Pubmed PMID: 20736998
- Reid JG, Nagaraja AK, Lynn FC, Drabek RB, Muzny DM, Shaw CA, Weiss MK, Naghavi AO, Khan M, Zhu H, Tennakoon J, Gunaratne GH, Corry DB, Miller J, McManus MT, German MS, Gibbs RA, Matzuk MM, Gunaratne PH "Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes.." Genome Res.. 2008 Oct;18(10):1571-81. Pubmed PMID: 18614752
- Shan M, Cheng HF, Song LZ, Roberts L, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Storness-Bliss C, Ramchandani M, Lee SH, Corry DB, Kheradmand F "Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.." Sci Transl Med. 2009 Oct 28;1(4):4ra10. Pubmed PMID: 20368170
- Porter P, Susarla SC, Polikepahad S, Qian Y, Hampton J, Kiss A, Vaidya S, Sur S, Ongeri V, Yang T, Delclos GL, Abramson S, Kheradmand F, Corry DB "Link between allergic asthma and airway mucosal infection suggested by proteinase-secreting household fungi.." 2009 Nov;2(6):504-17. Pubmed PMID: 19710638
- Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, Locksley RM "Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.." J. Exp. Med.. 1996 Jan 1;183(1):109-17. Pubmed PMID: 8551213
- Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C "Interleukin 25 promotes the initiation of proallergic type 2 responses.." J. Exp. Med.. 2007 Jul 9;204(7):1509-17. Pubmed PMID: 17562814
- Wang ZE, Zheng S, Corry DB, Dalton DK, Seder RA, Reiner SL, Locksley RM "Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major.." Proc. Natl. Acad. Sci. U.S.A.. 1994 Dec 20;91(26):12932-6. Pubmed PMID: 7809149
- Chavez J, Young HW, Corry DB, Lieberman MW "Interactions between leukotriene C4 and interleukin 13 signaling pathways in a mouse model of airway disease.." Arch. Pathol. Lab. Med.. 2006 Apr;130(4):440-6. Pubmed PMID: 16594735
- Corry DB, Kheradmand F "Induction and regulation of the IgE response.." Nature. 1999 Nov 25;402(6760):B18-23. Pubmed PMID: 10586891
- Corry DB "IL-13 in allergy: home at last.." Curr. Opin. Immunol.. 1999 Dec;11(6):610-4. Pubmed PMID: 10631543
- Sawa T, Corry DB, Gropper MA, Ohara M, Kurahashi K, Wiener-Kronish JP "IL-10 improves lung injury and survival in Pseudomonas aeruginosa pneumonia.." J. Immunol.. 1997 Sep 15;159(6):2858-66. Pubmed PMID: 9300709
- Singh M, Lee SH, Porter P, Xu C, Ohno A, Atmar RL, Greenberg SB, Bandi V, Gern J, Amineva S, Aminev A, Skern T, Smithwick P, Perusich S, Barrow N, Roberts L, Corry DB, Kheradmand F "Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease.." J. Allergy Clin. Immunol.. 2010 Jun;125(6):1369-1378.e2. Pubmed PMID: 20430426
- Roth I, Corry DB, Locksley RM, Abrams JS, Litton MJ, Fisher SJ "Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10.." J. Exp. Med.. 1996 Aug 1;184(2):539-48. Pubmed PMID: 8760807
- Lee SH, Corry DB "Homing alone? CD18 in infectious and allergic disease.." Trends Mol Med. 2004 Jun;10(6):258-62. Pubmed PMID: 15177189
- Shearer WT, Corry DB "High prevalence of asthma in HIV-infected adults: New insights.." J. Allergy Clin. Immunol.. 2012 Mar;129(3):715-6. Pubmed PMID: 22296750
- Pakdaman MN, Corry DB, Luong A "Fungi linking the pathophysiology of chronic rhinosinusitis with nasal polyps and allergic asthma.." Immunol. Invest.. 2011;40(41463):767-85. Pubmed PMID: 21985305
- Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M "Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.." J. Immunol.. 2008 May 1;180(9):6000-9. Pubmed PMID: 18424720
- Van Dyken SJ, Garcia D, Porter P, Huang X, Quinlan PJ, Blanc PD, Corry DB, Locksley RM "Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration.." J. Immunol.. 2011 Sep 1;187(5):2261-7. Pubmed PMID: 21824866
- Xu J, Park PW, Kheradmand F, Corry DB "Endogenous attenuation of allergic lung inflammation by syndecan-1.." J. Immunol.. 2005 May 1;174(9):5758-65. Pubmed PMID: 15843578
- Hong JS, Greenlee KJ, Pitchumani R, Lee SH, Song LZ, Shan M, Chang SH, Park PW, Dong C, Werb Z, Bidani A, Corry DB, Kheradmand F "Dual Protective Mechanisms of Matrix Metalloproteinases 2 and 9 in Immune Defense against Streptococcus pneumoniae.." J. Immunol.. 2011 Jun 1;186(11):6427-36. Pubmed PMID: 21508260
- Goswami S, Angkasekwinai P, Shan M, Greenlee KJ, Barranco WT, Polikepahad S, Seryshev A, Song LZ, Redding D, Singh B, Sur S, Woodruff P, Dong C, Corry DB, Kheradmand F "Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma.." Nat. Immunol.. 2009 May;10(5):496-503. Pubmed PMID: 19329997
- Vargas-Inchaustegui DA, Tai W, Xin L, Hogg AE, Corry DB, Soong L "Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice.." Infect. Immun.. 2009 Jul;77(7):2948-56. Pubmed PMID: 19364834
- Kheradmand F, Corry DB "Discovery of novel markers in allergic lung inflammation through proteomic-based technologies.." 2008 Feb;5(1):41529. Pubmed PMID: 18282117
- Lee SH, Prince JE, Rais M, Kheradmand F, Shardonofsky F, Lu H, Beaudet AL, Smith CW, Soong L, Corry DB "Differential requirement for CD18 in T-helper effector homing.." Nat. Med.. 2003 Oct;9(10):1281-6. Pubmed PMID: 14502280
- Corry DB, Reiner SL, Linsley PS, Locksley RM "Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis.." J. Immunol.. 1994 Nov 1;153(9):4142-8. Pubmed PMID: 7523517
- Lee SH, Prince JE, Rais M, Kheradmand F, Ballantyne CM, Weitz-Schmidt G, Smith CW, Corry DB "Developmental control of integrin expression regulates Th2 effector homing.." J. Immunol.. 2008 Apr 1;180(7):4656-67. Pubmed PMID: 18354189
- Corry DB, Rishi K, Kanellis J, Kiss A, Song Lz LZ, Xu J, Feng L, Werb Z, Kheradmand F "Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency.." Nat. Immunol.. 2002 Apr;3(4):347-53. Pubmed PMID: 11887181
- Corry DB, Lewis DE "Cytokine storm and an anti-CD28 monoclonal antibody.." N. Engl. J. Med.. 2006 Dec 14;355(24):2592; author re. Pubmed PMID: 17171820
- Corry DB, Ampel NM, Christian L, Locksley RM, Galgiani JN "Cytokine production by peripheral blood mononuclear cells in human coccidioidomycosis.." J. Infect. Dis.. 1996 Aug;174(2):440-3. Pubmed PMID: 8699085
- Drouin SM, Corry DB, Kildsgaard J, Wetsel RA "Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy.." J. Immunol.. 2001 Oct 15;167(8):4141-5. Pubmed PMID: 11591733
- Hesselbacher SE, Ross R, Schabath MB, Smith EO, Perusich S, Barrow N, Smithwick P, Mammen MJ, Coxson H, Krowchuk N, Corry DB, Kheradmand F "Cross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokers.." Int J Environ Res Public Health. 2011 May;8(5):1324-40. Pubmed PMID: 21655122
- Corry DB, Locksley RM "Construction of polycompetitors for competitive PCR.." Methods Mol. Med.. 1999;26:253-64. Pubmed PMID: 21340883
- Reiner SL, Zheng S, Corry DB, Locksley RM "Constructing polycompetitor cDNAs for quantitative PCR.." J. Immunol. Methods. 1993 Sep 27;165(1):37-46. Pubmed PMID: 8409467
- Reiner SL, Zheng S, Corry DB, Locksley RM "Constructing polycompetitor cDNAs for quantitative PCR (J. Immunol. Methods 165 (1993) 37-46).." J. Immunol. Methods. 1994 Jul 12;173(1):133. Pubmed PMID: 8034981
- Reiner SL, Zheng S, Corry DB, Locksley RM "Constructing polycompetitor cDNAs for quantitative PCR (J. Immunol. Methods 165 (1993) 37-46; 173(1994) 133).." J. Immunol. Methods. 1994 Oct 14;175(2):275. Pubmed PMID: 7930655
- Shan M, Yuan X, Song LZ, Roberts L, Zarinkamar N, Seryshev A, Zhang Y, Hilsenbeck S, Chang SH, Dong C, Corry DB, Kheradmand F "Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema.." Sci Transl Med. 2012 Jan 18;4(117):117ra9. Pubmed PMID: 22261033
- Brown DR, Fowell DJ, Corry DB, Wynn TA, Moskowitz NH, Cheever AW, Locksley RM, Reiner SL "Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses.." J. Exp. Med.. 1996 Oct 1;184(4):1295-304. Pubmed PMID: 8879201
- Hadeiba H, Corry DB, Locksley RM "Baseline airway hyperreactivity in A/J mice is not mediated by cells of the adaptive immune system.." J. Immunol.. 2000 May 1;164(9):4933-40. Pubmed PMID: 10779804
- Xu C, Hesselbacher S, Tsai CL, Shan M, Spitz M, Scheurer M, Roberts L, Perusich S, Zarinkamar N, Coxson H, Krowchuk N, Corry DB, Kheradmand F "Autoreactive T Cells in Human Smokers is Predictive of Clinical Outcome.." Front Immunol. 2012;3:267. Pubmed PMID: 22969766
- Kheradmand F, Shan M, Xu C, Corry DB "Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidence.." Expert Rev Clin Immunol. 2012 Mar;8(3):285-92. Pubmed PMID: 22390492
- Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson HO, Cogswell S, Storness-Bliss C, Corry DB, Kheradmand F "Antielastin autoimmunity in tobacco smoking-induced emphysema.." Nat. Med.. 2007 May;13(5):567-9. Pubmed PMID: 17450149
- Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, Kheradmand F "An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema.." PLoS Med.. 2004 Oct;1(1):e8. Pubmed PMID: 15526056
- Lee SH, Kiss A, Xu J, Qian Y, Bashoura L, Kheradmand F, Corry DB "Airway glycoprotein secretion parallels production and predicts airway obstruction in pulmonary allergy.." J. Allergy Clin. Immunol.. 2004 Jan;113(1):72-8. Pubmed PMID: 14713910
- Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA "Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.." J. Immunol.. 2002 Nov 15;169(10):5926-33. Pubmed PMID: 12421977
- Polikepahad S, Barranco WT, Porter P, Anderson B, Kheradmand F, Corry DB "A reversible, non-invasive method for airway resistance measurements and bronchoalveolar lavage fluid sampling in mice.." J Vis Exp. 2010;(38) Pubmed PMID: 20389278
- Kheradmand F, Kiss A, Xu J, Lee SH, Kolattukudy PE, Corry DB "A protease-activated pathway underlying Th cell type 2 activation and allergic lung disease.." J. Immunol.. 2002 Nov 15;169(10):5904-11. Pubmed PMID: 12421974
- Kiss A, Montes M, Susarla S, Jaensson EA, Drouin SM, Wetsel RA, Yao Z, Martin R, Hamzeh N, Adelagun R, Amar S, Kheradmand F, Corry DB "A new mechanism regulating the initiation of allergic airway inflammation.." J. Allergy Clin. Immunol.. 2007 Aug;120(2):334-42. Pubmed PMID: 17544098
- Corry DB, Kheradmand F "A new link to airway obstruction in asthma.." Nat. Med.. 2007 Jul;13(7):777-8. Pubmed PMID: 17618262
Funding
- Immunology Scientist Training Grant - #T32 AI053831
- $383,692.00 (01/01/2008 - 08/31/2019) Grant funding from NIH
- Fungal Pathogenesis of Moderate to Severe Asthma - #R01 AI135803
- $337,685.00 (03/01/2018 - 03/01/2023) Grant funding from NIH
- Mechanism and Function of Let-7, A Novel Modulator of Th17-Dependent Emphysema - #R01 HL140398
- $272,806.00 (09/01/2018 - 09/01/2023) Grant funding from NIH
- Molecular and Cellular Dissection of miRNAs in Controlling Allergic Airway Inflammation in Mice - #I01BX004828
- $610,000.00 (07/01/2020 - 06/30/2024) Grant funding from VA-ORD
Intellectual Property
- Product Patent #9,765,099 (Approved)
- Co Inventors: John McMurray, John Moran Knight, Pietro Mordicchi, Pijus Mandal
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