Andre Catic, M.D., Ph.D.
Picture
Positions
- Assistant Professor & CPRIT Scholar in Cancer Research
-
since 2014
Huffington Center on Aging
Baylor College of Medicine
Houston, Texas United States
- Instructor in Medicine
-
2007-2014
Center for Regenerative Medicine
Massachusetts General Hospital
Boston, Massachusetts United States
- Research Fellow
-
2007-2014
Harvard Stem Cell Institute
Boston, Massachusetts United States
- Post-doctoral Associate
-
2006
Whitehead Institute/MIT
Cambridge, Massachusetts United States
- Medical Resident
-
2000-2001
Charité Hospital
Berlin, Germany
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Education
- MD from University of Ulm
- 10/1999 - Ulm, Germany
- PhD from Harvard University
- 06/2006 - Cambridge, MA United States
Professional Interests
- We study protein quality control mechanisms and their involvement in gene regulation, metabolism, and aging.
Professional Statement
Transcription factors are key determinants of cellular metabolism and developmental potential. Their short lifespan allows cells to react quickly to changes in environment and fate. However, it remains largely unexplored how the removal of these regulators affects gene expression and facilitates cellular adaption.Dr. Catic’s research aims to define the degradation patterns of transcription factors in the context of metabolism, aging, stem cell and cancer biology. The goal of these studies is to change the turnover of select transcription factors and thereby alter distinct genetic programs.
Websites
Selected Publications
- "The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes." Sci Rep.. 2020; Pubmed PMID: 32811853
Funding
- Transcript decay regulates hematopoietic aging - #R01DK115454 Grant funding from NIDDK
Log In to edit your profile