Selected Publications
- Konduri V, Joseph SK, Byrd TT, Nawas Z, Vazquez-Perez J, Hofferek CJ, Halpert MM, Liu D, Liang Z, Baig Y, Oyewole-Said D, Tsimelzon A, Burns B, Chen C, Levitt JM, Yao Q, Ahmed NM, Hegde M, Decker WK. (2021). A Subset of Cytotoxic Effector Memory T cells Enhances CAR T cell Efficacy in a Model of Pancreatic Ductal Adenocarcinoma. Science Translational Medicine. In Press.
- Phoebe E. Lewis, Ethan C. Poteet, Dongliang Liu, Changyi Chen, Celia C. LaBranche, Sherry A. Stanfield-Oakley, David C. Montefiori, Guido Ferrari, and Qizhi Yao. (2020). CTLA-4 Blockade, during HIV Virus-Like Particles Immunization, Alters HIV-Specific B-Cell Responses. Vaccines. 8(2), 284.
- Eugene Lurie, Dongliang Liu, Emily L. LaPlante, Lillian R. Thistlethwaite, Qizhi Yao*, and Aleksandar Milosavljevic*. (2020). Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin. Oncogenesis. 9:62. *Co-corresponding authors.
- Duo Liu, Dan Zhou, Yanfa Sun, Jingjing Zhu, Dalia Ghoneim, Chong Wu, Qizhi Yao, Eric R. Gamazon, Nancy J. Cox, Lang Wu. (2020). Identification of candidate susceptibility genes for pancreatic cancer risk: A Transcriptome-Wide Association Study. Cancer Research. 80(20):4346-4354. doi: 10.1158/0008-5472.CAN-20-1353. Epub 2020 Sep 9.
- Poteet E, Liu D, Liang Z, Van Buren G, Chen C, Yao Q. (2019). Mesothelin and TGF-α predict pancreatic cancer cell sensitivity to EGFR inhibitors and effective combination treatment with trametinib. PLoS One. Mar 28;14(3):e0213294. doi: 10.1371/journal.pone.0213294. eCollection 2019 PMID: 30921351
- Ethan Poteet, Phoebe Lewis, Zhiyin Yu,Changyi Chen, Guojun Yang, Pramod N Nehete, K Jagannadha Sastry, Gary Fujii, Qizhi Yao. (2019). SHIV Virus-Like Particles (VLPs) Vaccination Induces Partial Protection from SHIV Challenge in a Rhesus Macaque Model. Journal of Vaccines and Vaccination. 10:406
- Lin-Kin Yong, Ethan Poteet, Changyi Chen, Qizhi Yao. (2018). Emerging roles of Semaphorin 3E in cancers. Trends in Cancer Research. 13: 113-129.
- Lin-Kin Yong, Syeling Lai, Zhengdong Liang, Ethan Poteet, Qianxing Mo, George Van Buren, William E. Fisher, Changyi Chen, Qizhi Yao. (2016) Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival. Oncotarget. 2016 Nov 29. doi: 10.18632/oncotarget.13704. [Epub ahead of print] PMID: 27911862.
- Ethan Poteet, Phoebe Lewis, Changyi Chen, Sam On Ho, Thai Do, SuMing Chiang, Celia Labranche, David Montefiori, Gary Fujii, Qizhi Yao. (2016). Toll-like Receptor 3 Adjuvant in Combination with Virus-like Particles Elicit a Strong Humoral Response Against HIV Vaccine. Vaccine, 2016 Nov 21;34(48):5886-5894. doi: 10.1016/j.vaccine.2016.10.036.
- Vanaja Konduri, Dali Li, Matthew M. Halpert, Dan Liang, Zhengdong Liang, Yunyu Chen, William E. Fisher, Silke Paust, Jonathan M. Levitt, Qizhi Cathy Yao*, William K. Decker*. (2016). Chemo-Immunotherapy Mediates Durable Cure of Orthotopic KrasG12D/p53-/- Pancreatic Ductal Adenocarcinoma. OncoImmunology. 2016 Jul 22;5(9):e1213933 *Co-corresponding authors. PMID: 27757308.
- Lü JM, Liang Z, Wang X, Gu J, Yao Q, Chen C. (2016). New polymer of lactic-co-glycolic acid-modified polyethylenimine for nucleic acid delivery. Nanomedicine (Lond). 2016 Aug;11(15):1971-91. doi: 10.2217/nnm-2016-0128. Epub 2016 Jul 26. PMID: 27456396
- Ethan Poteet, Phoebe Lewis, Changyi Chen, Sam On Ho, Thai Do, SuMing Chiang, Celia Labranche, David Montefiori, Gary Fujii, Qizhi Yao. (2016). Toll-like Receptor 3 Adjuvant in Combination with Virus-like Particles Elicit a Strong Humoral Response Against HIV Vaccine. Vaccine, 2016 Nov 21;34(48):5886-5894. doi: 10.1016/j.vaccine.2016.10.036.
- Rios A, Pottet EC, Siwak EB, Anderson DW, Yao QC. (2016). The Human Immune Response to HIV and Its Impact in the Potential Development of an Inactivated HIV Vaccine. AIDS Rev. 2016 Jul 19;18(3). [Epub ahead of print]. PMID: 27438575
- Ethan Poteet, Phoebe Lewis, Feng Li, Sheng Zhang, Jianhua Gu, Changyi Chen, Sam On Ho, Thai Do, SuMing Chiang, Gary Fujii, Qizhi Yao. (2015). A novel prime and boost regimen of HIV virus-like particles with TLR4 Adjuvant MPLA induces Th1 oriented immune responses against HIV. PlosOne. 10(8):e0136862. PMID: 26312747
- Marin-Muller, C., Li, D., Bharadwaj, U., Li, M., Chen, C., Hodges, SH., Fisher, WE., Mo, Q., Hung, MC., Yao Q. (2013). A Tumorigenic Factor Interactome Connected through Tumor Suppressor MicroRNA-198 in Human Pancreatic Cancer. Clinical Cancer Research, 19(21):5901-13.
- Zhang, S, Yong, L, Li D, Cubas, R, Chen, C, Yao, Q. (2013), Mesothelin virus-like particle immunization controls pancreatic cancer growth through CD8+ T cell induction and reduction in the frequency of CD4+foxp3+ICOS-regulatory T cells. PLoS One, 8(7):e68303.
- Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q. (2011), Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression. Mol Cancer, 10:106.
- Bharadwaj U, Marin-Muller C, Zhang Y, Li M, Chen C, Yao Q. (2011), Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation. Carcinogenesis, 32(7):1013-1024.
- Cubas R, Zhang S, Li M, Chen C, Yao Q. (2011), Chimeric Trop2 virus-like particles: a potential immunotherapeutic approach against pancreatic cancer. J Immunother, 34(3):251-263.
- Zhang S, Cubas R, Li M, Chen C, Yao Q. (2009), Virus-like particle vaccine activates conventional B2 cells and promotes B cell differentiation to IgG2a producing plasma cells. Mol Immunol, 46(10):1988-2001.