Medical Genetics Test Details
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KIT Mutations, Melanoma | ||
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Test Information: | Predicts response to tyrosine kinase inhibitor (TKI) therapy. Detects activating mutations in KIT and PDGFRA. | |
Test Details | ||
Test Code: | 9103 | |
Special Notes: | Samples received will be tested by ARUP. | |
Technical Information | ||
Methodology: | Polymerase Chain Reaction/Sequencing of exons 9, 11, 13, and 17 of the KIT gene and exons 12, 14, 18 of the PDGFRA gene | |
Gene Name: | KIT and PDGFRA | |
Protein Name: | KIT: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog PDGFRA: platelet-derived growth factor receptor alpha |
Sample & Shipping Information | ||
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Test Requisition: | Tumor Analysis | |
Specimen Type: | FFPE - Slide(s) | |
Requirements: | 5 unstained 5um FFPE slides (Min: 4 slides) containing adequate amounts of tumor to be analyzed. Please include a copy of corresponding surgical pathology report. |
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Shipping Conditions: | Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months. Unacceptable Conditions: Less than 50 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives. Decalcified specimens. Stability: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable |
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Specimen Type: | FFPE - Tumor Block | |
Requirements: | Paraffin-embedded, formalin-fixed (10 percent neutral buffered formalin) tissue block containing adequate amounts of tumor to be analyzed. Please include a copy of corresponding surgical pathology report. |
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Shipping Conditions: | Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months. Unacceptable Conditions: Less than 50 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives. Decalcified specimens. Stability: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable |
Turn Around Time: | 10-12 days | |
Billing Information | ||
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List Price: | *For Insurance or Institutional Prices, please call. | |
CPT Codes: | 88381 x 1, 81272 x 1, 81314 x 1 |