Medical Genetics Test Details

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The American Medical Association (AMA) Current Procedural Terminology (CPT) codes and Healthcare Common Procedure Coding System (HCPCS) codes listed, are provided for informational purposes only. The codes reflect our interpretation of CPT/HCPCS coding requirements based upon AMA guidelines published annually. CPT/HCPCS codes are provided only as guidance to assist clients with billing. Baylor Genetics strongly recommends that clients confirm CPT/HCPCS codes with their Medicare Administrative Contractor (MAC) or other payer being billed, as requirements may differ. CPT coding is the sole responsibility of the billing party. Baylor Genetics assumes no responsibility for billing errors due to reliance on the CPT codes listed. Please direct any questions regarding CPT coding to the payer being billed.

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NPM1 Mutation Detection by RT-PCR, Quantitative
Test Information:	Detect and quantify NPM1 mutant transcripts (types A, B, and D). Detect NPM1 mutations at diagnosis in patients with acute myeloid leukemia (AML) for initial prognostication. Monitor levels of mutant NPM1 transcripts during treatment in patients with NPM1-mutated acute myeloid leukemia and assess minimal residual disease (MRD).
Test Details
Test Code:	9005
Special Notes:	Samples received will be tested by ARUP.
Technical Information
Methodology:	Quantitative Reverse-Transcription Polymerase Chain Reaction
Gene Name:	NPM1
Protein Name:	Nucleophosmin/Nucleoplasmin Family, member 1

Sample & Shipping Information
Test Requisition:	Tumor Analysis
Specimen Type:	Bone Marrow
Requirements:	Draw bone marrow in an EDTA (purple-top) tube(s) and send 3 mL (Min: 1 mL). Specimens must be received within 48 hours of collection due to lability of RNA.
Shipping Conditions:	CRITICAL REFRIGERATED. Separate specimens must be submitted when multiple tests are ordered. Unacceptable Conditions: Serum, plasma, or FFPE tissue. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens. Stability: Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable
Specimen Type:	Whole Blood
Requirements:	Draw whole blood in an EDTA (purple-top) tube(s) and send 5 mL (Min: 1 mL).
Shipping Conditions:	CRITICAL REFRIGERATED. Separate specimens must be submitted when multiple tests are ordered. Unacceptable Conditions: Serum, plasma, or FFPE tissue. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens. Stability: Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable

Billing Information
Turn Around Time:	5-7 days
List Price:	*For Insurance or Institutional Prices, please call.
CPT Codes:	81310x1

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