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Genetic Labs

Houston, Texas

Genetic Laboratory
Baylor Genetics Laboratories
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Medical Genetics Test Details

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The American Medical Association (AMA) Current Procedural Terminology (CPT) codes and Healthcare Common Procedure Coding System (HCPCS) codes listed, are provided for informational purposes only. The codes reflect our interpretation of CPT/HCPCS coding requirements based upon AMA guidelines published annually. CPT/HCPCS codes are provided only as guidance to assist clients with billing. Baylor Genetics strongly recommends that clients confirm CPT/HCPCS codes with their Medicare Administrative Contractor (MAC) or other payer being billed, as requirements may differ. CPT coding is the sole responsibility of the billing party. Baylor Genetics assumes no responsibility for billing errors due to reliance on the CPT codes listed. Please direct any questions regarding CPT coding to the payer being billed.


ClariFindTM Comprehensive DNA Panel
Test Information: ClariFind interrogates all coding regions (+/- 5-10 bp flanking intronic sequences) of 277 key cancer genes for both solid tumors and hematologic malignancies. Genomic alterations detected in these genes include important diagnostic, prognostic, and predictive biologic markers. Through the use of a unique molecular barcoding approach, which allows for amplification-based target enrichment (ideal for tumor samples with limited starting material) but with the ability to account for each unique starting molecule, our assay mitigates PCR duplicates and bias and allows for confident low-level variant detection. Additionally, the chemistry is designed for improved coverage of GC-rich regions in genes such as CEBPA and CCND1. Each ClariFind report provides annotated genomic findings, associated targeted therapies, and potential clinical trials when available.
Test Details
Test Code: 20010
Special Notes: This panel is designed to identify single nucleotide changes, copy number alterations (39 genes), and indels. For further details and a complete gene list, please visit baylorgenetics.com/Clarifind.
Technical Information
Methodology: Amplicon-based targeted next-generation sequencing utilizing unique molecular identifiers
Test Type: Next Generation Sequencing
Sample & Shipping Information
Test Requisition: Tumor Analysis
Specimen Type: Blood or Bone Marrow
Requirements: 3-5 cc (2 yrs-adult), 2-3 cc (newborn-2 yrs) in EDTA (purple-top) tube.
Attach clinical notes and concurrent laboratory reports (such as CBC, flow cytometry, cytogenetics, FISH, molecular testing, and pathology reports). Concurrent laboratory reports may be sent later as soon as they become available.
Shipping Conditions: Ship at room or refrigerated temperature in an insulated container by overnight courier. Do not heat or freeze. Specimen should arrive in laboratory within 24-48 hours of collection.

Specimen Type: DNA (Extracted)
Requirements: At least 100 ng with minimum concentration of 25 ng/L. Attach clinical notes, concurrent laboratory reports, and/or surgical pathology report, as applicable. Please send a corresponding representative H&E slide if available.

Extracted DNA/RNA will only be accepted if the isolation of nucleic acids for clinical testing occurs in a CLIA-certified laboratory or a laboratory meeting equivalent requirements as determined by the CAP and/or the CMS.
Shipping Conditions: Ship at room or refrigerated temperature in an insulated container by overnight courier. May also be shipped frozen on minimum of 10 lbs. of dry ice in an insulated container by overnight courier.

Specimen Type: FFPE Block
Requirements: Paraffin-embedded, formalin-fixed tissue block containing >20% tumor nuclei with a minimum tumor surface area of 5 mm x 5 mm (25 mm2).
A surgical pathology report MUST be attached for all tissue samples.
Shipping Conditions: Ship at room temperature in an insulated container by overnight courier.
If shipping during the summer months, please include a cold-pack to avoid extreme temperatures. Do not heat or freeze.

Unacceptable Conditions: Decalcified specimens are not accepted.


Specimen Type: FFPE Slide(s)
Requirements: 10-15 unstained 5 m FFPE slides containing >20% tumor nuclei with a minimum tumor surface area of 5 mm x 5 mm (25 mm2). For smaller specimens, 20 or more unstained 5 m FFPE slides containing >20% tumor nuclei should be submitted. A surgical pathology report MUST be attached for all tissue samples.
Shipping Conditions: Ship at room temperature in an insulated container by overnight courier.
If shipping during the summer months, please include a cold-pack to avoid extreme temperatures. Do not heat or freeze.

Unacceptable Conditions: Decalcified specimens are not accepted.


Specimen Type: Fresh Frozen Tissue
Requirements: 150 mg fresh tissue snap frozen at <-20C. Store at <-20C.
A surgical pathology report MUST be attached for all tissue samples. Surgical pathology report may be sent later as soon as it becomes available.
Shipping Conditions: Ship on minimum of 10 lbs. of dry ice in an insulated container by overnight courier.

Specimen Type: Fresh Tissue in Medium
Requirements: 0.5-1 cm3 or more fresh tissue in a sterile, screw-top container filled with tissue culture transport medium. If tissue culture transport medium is not available, collect in plain RPMI, Hanks solution, or saline. Please send a corresponding representative H&E slide if available. A surgical pathology report MUST be attached for all tissue samples. Surgical pathology report may be sent later as soon as it becomes available.
Shipping Conditions: Ship at refrigerated or room temperature in an insulated container by overnight courier. Do not heat or freeze. Specimen should arrive in laboratory within 48 hours of collection.

Turn Around Time: 14 days
Billing Information
List Price: *For Insurance or Institutional Prices, please call.
CPT Codes: 81455 x 1


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