Medical Genetics Test Details
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|KIT Exon 9 & 11 Mutation Analysis - Germline|
|Test Information:||Indication for Study:
To distinguish germ line mutation from somatic mutation when a novel mutation(s) is identified.
Sequencing analysis of the region(s) containing the novel mutation(s) is performed in the forward and reverse directions in germ line cells|
This test can only be performed if there is a previously identified novel mutation(s) identified in KIT Exon 9 & 11 Mutation Analysis performed on FFPE samples (#9110) or Fresh Frozen Tissue (#9111). Only exon(s) containing the novel mutation(s) will be sequenced. If the original novel mutation(s) was identified in another laboratory, this testing must be discussed with one of our genetic counselors prior to sending a specimen.
This test is designed to distinguish germ line mutation from somatic mutation. The limit of the test is approximately 20 mutated cells in 100 total cells (20%).
Results of this test must always be interpreted in the context of relevant clinical and pathological data, and should not be used alone for a diagnosis of malignancy. This test is not intended to detect minimal residual disease.
- Optimal Use of Targeted Agents for Advanced Gastrointestinal Stromal Tumours
|Methodology:||Sequencing analysis of the region(s) containing the novel mutation(s) is performed in the forward and reverse directions in germ line cells
|Protein Name:||v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog|
|Test Type:||Mutation Analysis|
|Sample & Shipping Information|
|Test Requisition:||Tumor Analysis|
|Requirements:||Draw blood in an EDTA (purple-top) tube(s) and send 3-5 cc (Adults/Children) and 3 cc (Infant<2yrs).|
|Shipping Conditions:||Ship at ambient temperature (18-25°C/64-77°F) in an insulated container by overnight courier. Do not heat or freeze.
|Turn Around Time:||10 - 14 days|
|List Price:||*For Insurance or Institutional Prices, please call.|