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  T. Chao

Hsiao-Tuan Chao, Post-doc

Phone: 713-798-3540

Joined the lab: May 2005

1999-2002: University of Texas at Austin, BA in Plan II Honors, BS in Biochemistry
2002-current: Baylor College of Medicine, Medical Scientist Training Program, Department of Neuroscience.

  Project: Role of Excitation and Inhibition in Rett Syndrome.

Rett syndrome (RTT) is a progressive neurodevelopmental disease caused by mutations in the X-linked gene encoding the transcriptional repressor, methyl-CpG-binding protein 2 (MECP2) gene.  Classic RTT manifests in female patients by the onset of tremors, seizures, stereotypies, loss of motor skills, and social behavioral abnormalities including lack of communication, and withdrawn behavior reminiscent of features seen in autistic patients. I hypothesize that MeCP2 dysfunction results in abnormal excitatory-inhibitory neuronal activity, which ultimately contributes to altered social behavior and stereotyped behavior.

  Hobbies or interests:
Gardening…as much as one can with a balcony.

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Last Modified: July 27, 2010