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Zechiedrich Laboratory

Houston, Texas

Supercoils in architecture echo the structure of DNA.
Zechiedrich Lab
not shown on screen

Kimberly M. Carlson-Banning

Photo Kimberly Carlson

Graduate Student
March 2010 - August 2013
Verna and Marrs McLean Department of Biochemistry and Molecular Biology

E-mail: kcarlson@bcm.edu
Phone: 713-798-5127
Fax: 713-798-7375

Research interest

Multi-drug resistant bacterial infections directly cause or contribute to ~100,000 deaths and cost over $3 billion dollars annually in the United States alone. The current antibiotic development pipeline is drying up, and the drugs in development are subject to existing drug resistance mechanisms. My research, in collaboration with Dr. Yongcheng Song in the Pharmacology Department, has focused on finding new compounds that are effective against multi-drug resistant E. coli, K. pneumoniae, and A. baumannii clinical isolates collected from local Houston hospitals. We have identified many compounds, and I am currently exploring through genetic screens and biochemical assays how our most promising compound functions in killing these drug resistant bacteria.

Professional Societies

American Society for Microbiology (since 2010)


Talks/Poster Presentations

Poster - Molecular Basis of Infectious Diseases Retreat Mar. 23, 2012

Talk- Verna and Marrs McLean Department of Biochemistry and Molecular Biology Annual Retreat Oct. 13-14, 2011

Poster- 111th General Meeting of the American Society for Microbiology May 21-24, 2011

Poster- Verna and Marrs McLean Department of Biochemistry and Molecular Biology Annual Retreat Oct. 13-14, 2010

Poster- BCM Graduate Student Symposium Oct. 2010

Poster- Verna and Marrs McLean Department of Biochemistry and Molecular Biology Annual Retreat Oct. 15-16, 2009

Poster- Verna and Marrs McLean Department of Biochemistry and Molecular Biology Annual Retreat Oct. 16-17, 2008

Publications

Carlson-Banning, K.M., Chou, A., Liu, Z., Hamill, R.J., Song, Y., and Zechiedrich, L. Toward repurposing ciclopirox as an antibiotic against drug-resistant Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae. PLOS ONE.

Swick, M.C., Morgan-Linnell, S.K., Carlson, K.M., and Zechiedrich, L. (2011). Expression of multidrug efflux pump genes acrAB-tolC, mdfA, and norE in Escherichia coli clinical isolates as a function of fluoroquinolone and multidrug resistance. Antimicrob. Agents Chemother. 55, 921-924

Awards

2nd place poster award, Molecular Basis of Infectious Diseases Retreat Houston, TX. Mar. 2012

Honorary Talk Award, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Annual Retreat Oct. 2011.