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BCM - Baylor College of Medicine

Giving life to possible

James Martin Lab

About the Lab

The main research interest of the Martin Lab is the study of molecular mechanisms controlling cell growth and differentiation in embryogenesis and their relation to congenital heart defects and heart muscle regeneration.

The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article.  Our lab is currently working to develop methods to remove Hippo signaling using small molecules that may prove useful to treat human patients that have suffered heart muscle destruction after a myocardial infarct (MI).