H. Xu, S.O. Skinner, A.M. Sokac, I. Golding. "Stochastic Kinetics of Nascent RNA." Physical Review Letters, 2016 September 13. [Physical Review Letters]
I. Golding. "Single-Cell Studies of Phage λ: Hidden Treasures Under Occam's Rug." Annual Review of Virology, 2016 July 22. [Annual Reviews]
L. Figard, M. Wang, L. Zheng, I. Golding, A.M. Sokac. "Membrane Supply and Demand Regulates F-Actin in a Cell Surface Reservoir." Developmental Cell, 2016 May 9. [Developmental Cell]
L.A. Sepúlveda, H. Xu, J. Zhang, M. Wang, I. Golding. "Measurement of gene regulation in individual cells reveals rapid switching between promoter states." Science, 2016 March 11. [Science]
S.O. Skinner, H. Xu, S. Nagarkar-Jaiswal, P.R. Freire, T.P. Zwaka, I. Golding. "Single-cell analysis of transcription kinetics across the cell cycle." eLife, 2016 January 29. [eLife] See also eLife Insight.
T.Y.-T. Hsu, ..., S.O. Skinner, ..., I. Golding, ..., T.F. Westbrook. "The spliceosome is a therapeutic vulnerability in MYC-driven cancer." Nature, 2015 Sept. 02. doi:10.1038 [Nature]
Xu, L.A. Sepúlveda, L. Figard, A.M. Sokac, I. Golding. “Combining protein and mRNA quantification to decipher transcriptional regulation.” Nature Methods, 2015 June 22 [PubMed]
Fei, D. Singh, Q. Zhang, S. Park, D. Balasubramanian, I. Golding, C.K. Vanderpool, T. Ha. “Determination of in vivo target search kinetics of regulatory noncoding RNA.” Science, 2015 March 20;347(6228):1371-74 [PubMed]
A.J. Gordon, D Satory, M. Wang, J.A. Halliday, I. Golding, C. Herman. “Removal of 8-oxo-GTP by MutT hydrolase is not a major contributor to transcriptional fidelity.” Nucleic Acids Research, 2014 Oct 29;42(19):12015-2 [PubMed]
Koirala, P.J. Mears, M. Sim, I. Golding, Y.R. Chemla, P.D. Aldridge, C.V. Rao. “A Nutrient-Tunable Bistable Switch Controls Motility in Salmonella enterica Serovar Typhimurium.” mBio, 2014 August 26;5(5):e01611-14 [PubMed]
Bednarz, J.A. Halliday, C. Herman, I. Golding. "Revisiting Bistability in the Lysis/Lysogeny Circuit of Bacteriophage Lambda." PloS one 9 (6), e100876 [PubMed]
P.J. Mears, S. Koirala, C.V. Rao, I. Golding, Y.R. Chemla. "Escherichia coli swimming is robust against variations in flagellar number." eLife 2014 Feb 11;3:e01916. [PubMed]
Figard, H. Xu, H.G. Garcia, I. Golding, A.M. Sokac. "The Plasma Membrane Flattens Out to Fuel Cell-Surface Growth during Drosophila Cellularization." Dev Cell. 2013 Dec 23;27(6):648-55 [PubMed]
Zheng, L.A. Sepúlveda, R.C. Lua, O. Lichtarge, I. Golding, A.M. Sokac. "The Maternal-to-Zygotic Transition Targets Actin to Promote Robustness during Morphogenesis." PLoS Genet., 9(11): e1003901. [PubMed]
S.O. Skinner, L.A. Sepúlveda, H. Xu, I. Golding. "Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization." Nat. Protoc. 2013 Jun;8(6):1100-13. [PubMed] See also: Human Frontier Science Program
L. Min, P. J. Mears, I. Golding, Y.R. Chemla. "Chemotactic adaptation kinetics of individual Escherichia coli cells." Proc. Natl. Acad. Sci. USA, 2012 Jun 19;109(25):9869-74. Epub 2012 Jun 7. [PubMed]
J.D. Kessler, ..., S.O. Skinner, ..., I. Golding, ..., T.F. Westbrook. "A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis." Science, 2012 Jan 20;335(6066):348-53 [PubMed]
Zeng, I. Golding. "Following Cell-fate in E. coli After Infection by Phage Lambda." J Vis Exp, 2011 Oct 14;(56) [PubMed]
Zhang, E. Rothenberg, G. Fruhwirth, P. D. Simonson, F. Ye, I. Golding, T. Ng, W. Lopes, P. R. Selvin. "Two-photon 3D FIONA of individual quantum dots in an aqueous environment." Nano Lett.2011 Oct 12;11(10):4074-8 [PubMed]
Mir, Z. Wang, Z. Shen, M. Bednarz, R. Bashir, I. Golding, S. G. Prasanth, and G. Popescu. "Optical measurement of cycle-dependent cell growth." Proc. Natl. Acad. Sci. USA, 2011 Aug 9;108(32):13124-9 [PubMed] See also: UIUC press
Rothenberg, L. A. Sepúlveda, S. O. Skinner, L. Zeng, P. R. Selvin, and I. Golding. "Single-Virus Tracking Reveals a Spatial Receptor-Dependent Search Mechanism." Biophys. J., 2011 Jun 22;100(12):2875-82 [PubMed]
Golding. "Decision Making in Living Cells: Lessons from a Simple System." Annual Review of Biophysics, 2011 Jun 9;40:63-80 [PubMed]
L.-h. So, A. Ghosh, C. Zong, L. A. Sepúlveda, R. Segev, and I. Golding. "General properties of transcriptional time series in Escherichia coli." Nature Genetics, 2011 May 1. [PubMed] See also: Nature Reviews Genetics Research Highlights, Human Frontier Science Program
L.-h. So. Gene Regulation in Escherichia coli Beyond the 'Rate' Approximation. Ph.D. thesis. Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL.
Zong, L.-h. So, L. A. Sepúlveda, S. O. Skinner, and I. Golding. "Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene." Molecular Systems Biology, 2010, 6:440 [PubMed]
Saini, S. Koirala, E. Floess, P. J. Mears, Y. R. Chemla,I. Golding, C. Aldridge, P. D. Aldridge, and C.V. Rao. "FliZ induces a kinetic switch in flagellar gene expression." J. Bacteriol., 2010 Dec;192(24):6477-81. [PubMed]
Zeng, S. O. Skinner, C. Zong, J. Sippy, M. Feiss and I. Golding. "Decision making at a subcellular level determines the outcome of bacteriophage infection." Cell, 2010 May 14, 141(4): 682-91. [PubMed] See also: BCM press, Nature Research Highlights
M. Min, P. J. Mears, L. M. Chubiz, C. V. Rao, I. Golding, and Y. R. Chemla. "High-resolution, long-term characterization of bacterial motility using optical tweezers." Nature Methods, 2009, 6, 831-5 [PubMed] See also: UIUC press
Chia, I. Golding and Nigel Goldenfeld. "Lambda-prophage induction modeled as a cooperative failure mode of lytic repression." Phys. Rev. E. Rapid Communications, 80, 030901 (R):1-4 (2009). [PubMed] See also: UIUC press
Wang, L. Guo, I. Golding, E. C. Cox and N. P. Ong. “Quantitative transcription factor binding kinetics at the single-molecule level.” Biophys. J.96 (2) 609-620 (2009).[PubMed]
I. Golding and E. C. Cox. “Spatiotemporal Dynamics in Bacterial Cells: Real-Time Studies with Single-Event Resolution.” In: H. W. Detrich, and J. J. Correia (Editors), Methods in Cell Biology, Vol. 89, Biophysical Tools for Biologists, Vol. 2: In Vivo Techniques, Academic Press (2008). [PubMed]
I. Golding and E. C. Cox. “Protein synthesis molecule by molecule.” Genome Biol. 7:212 (2006). [PubMed]
I. Golding and E. C. Cox. "Eukaryotic transcription: what does it mean for a gene to be 'on'?" Curr. Biol. 2006 May 23;16(10)R371-R373 [PubMed]
I. Golding and E. C. Cox. "Physical nature of bacterial cytoplasm." Phys. Rev. Lett. 2006 Mar 10;96(9):098 102. Epub 2006 Mar 10 [PubMed]
I. Golding, J. Paulsson, S. M. Zawilski and E. C. Cox. "Real-time kinetics of gene activity in individual bacteria." Cell, 2005, 123(6);1025-1036. [PubMed]
Y. M. Wang, J. O. Tegenfeldt, W. Reisner, R. Riehn, X.-J. Guan, L. Guo, I. Golding, E. C. Cox, J. Sturm and R. H. Austin. “Single-molecule studies of repressor-DNA interactions show long-range interactions.” Proc. Natl. Acad. Sci. USA 102 (28) 9796-9801 (2005). [PubMed]
Y. Chen, I. Golding, S. Sawai, L. Guo and E. C. Co. "Population fitness and the regulation of Escherichia coli genes by bacterial viruses." PloS Biol. 2005 Jul 3(7):e229. Epub 2005 June 21. [PubMed]
I. Golding and E. C. Cox. "RNA dynamics in live E. coli cells." Proc. Natl. Acad. Sci USA, 2004 Aug 3;101(31) 11310-11315. [PubMed]
U. Nevo, I. Golding, A. U. Neumann, M. Schwartz and S. Akselrod. “Autoimmunity as an immune defense against degenerative processes: a primary mathematical model illustrating the bright side of autoimmunity.” Journal of Theoretical biology 227 (4) 583-592 (2004). [PubMed]
U. Nevo, J. Kipnis, I. Golding, I. Shaked, A. Neumann, S. Akselrod and M. Schwartz. “Autoimmunity as a special case of immunity: removing threats from within.” Trends in Molecular Medicine 9 (3) 88-93 (2003). [PubMed]
I.G. Ron, I. Golding, B. Lifsitz-Mercer and E. Ben-Jacob. “Bursts of sectors in expanding bacterial colonies as a possible model for tumor growth and metastases.” Physica A 320 485-496 (2003).
O. Shefi, I. Golding, R. Segev, E. Ben-Jacob and A. Ayali. “Morphological characterization of in-vitro neuronal networks.” Phys. Rev. E. 66 (2) 021905 (2002). [PubMed]
I. Golding, B. Drossel, Y. Shapira and E. Ben-Jacob. “A Quantitative Study of the Dynamics of Adaptive Mutation Appearance.” Physica A 294 (1-2) 195-212 (2001).
I. Golding and E. Ben-Jacob. “The artistry of bacterial colonies and the antibiotic crisis” in Coherent Structures in Complex Systems (D. Reguera, L.L. Bonilla, and J.M. Rubí, Eds.), Springer-Verlag, Heidelberg (2001).
E. Ben-Jacob, I. Cohen, I. Golding, D.L. Gutnick, M. Tcherpakov, D. Helbing and I.G. Ron. “Bacterial cooperative organization under antibiotic stress.” Physica A 282 (1-2) 247-282 (2000).
I. Golding, I. Cohen and E. Ben-Jacob. “Studies of sector formation in expanding bacterial colonies.” Europhys. Lett. 48 (5) 587-593 (1999).
I. Cohen, I. Golding, Y. Kozlovsky and E. Ben-Jacob. “Continuous and discrete models of cooperation in complex bacterial colonies.” Fractals 7 (3) 235-247 (1999).
Y. Kozlovsky, I. Cohen, I. Golding and E. Ben-Jacob. “Lubricating bacteria model for branching growth of bacterial colonies.” Phys. Rev. E. 59 (6) 7025-7035 (1999).
I. Golding, Y. Kozlovsky, I. Cohen and E. Ben-Jacob. “Studies of bacterial branching growth using reaction-diffusion models of colonial development.” Physica A 260 (3-4) 510-554 (1998).
I. Golding and Y. Kantor. “Two-dimensional polymers with random short-range interactions.” Phys. Rev. E 56 (2) R1318-R1321 (1997).