N. Tony Eissa, M.D.
- Innate immunity
- Cellular regulation of misfolded proteins
- Cystic fibrosis
- Interstitial lung diseases
- Alpha one antitrypsin deficiency
Our laboratory is interested in two related aspects of innate immunity and inflammation. These are: the process of elimination of pathogens by autophagy and the regulation of nitric oxide synthesis by inducible nitric oxide synthase (iNOS). Our work on autophagy involves determining the molecular pathways regulating autophagy during pathogen infection. Autophagy has been recently shown to be an important component of the innate immune response by degrading foreign microbial invaders.