Andrew Sikora Lab

Projects

Master
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Lab members working together to conduct research.
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Collaboration

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Lab members working together to conduct research

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Dr. Sikora works with his lab members.
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Lab Leadership

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Dr. Sikora works with his lab members.

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The following are our key focus areas of research:

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Human Papillomavirus (HPV)-Associated Head and Neck Cancer

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Cancers of the throat (known as the “oropharynx”) caused by HPV have sharply increased over the past decade, and HPV-related oropharyngeal cancers are projected to exceed cervical cancers in the United States by the year 2020. We study the unique immunobiology of HPV-related cancer in mouse models and human clinical trials in order to develop new diagnostic and therapeutic approaches for this rapidly increasing cancer.

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Mechanisms of Cancer-Mediated Immune Suppression

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The focus of this research is understanding interactions of radiotherapy and chemotherapy with the immune system. Radiation has both immunosuppressive and immune stimulating effects. We have developed strategies for modeling the tumor immune microenvironment in order to unleash the beneficial immune stimulating effects of radiation-based therapies.

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Andrew Sikora Lab

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Neurosensory Building
6501 Fannin St.
5th Floor, Suite NA5
Houston, TX 77030

Contact: Lab Manager, Falguni Parikh, M.S.
Phone: (713) 798-8609
Email: falguni.parikh@bcm.edu

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Clinical Trials

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Clinical trials are conducted to test whether a new drug, prevention strategy, or screening test is safe and effective in people.