Andrew Sikora Lab

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Key Research Questions

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  • What are the cellular and molecular mechanisms by which cancer-induced inflammation leads to immunosuppression and cancer immune escape?
  • What is the impact of standard therapies – such as surgery, chemotherapy, and radiotherapy – on anti-tumor immunity and response to immunotherapies?
  • How can we use information about changes in the genomic, metabolic, and immunological profile of patients and their tumors to select the therapies most effective for their cancer?
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To answer these questions we perform studies in mouse- and chick egg-based model tumor systems; human cell and cell-line culture experiments; studies of patient samples collected before and after treatment; and clinical trials with new immune-based therapies.

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Andrew Sikora Lab

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Contact: Lab Manager, Falguni Parikh, M.S.
Phone: (713) 798-8609
Email: falguni.parikh@bcm.edu

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Learning to make a difference through science

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Hsuan-Chen Liu, Baylor College of Medicine graduate student in the Translational Biology and Molecular Medicine Program and Sikora Lab member talks about life as a student and researcher.

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Clinical Trials

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Clinical trials are conducted to test whether a new drug, prevention strategy, or screening test is safe and effective in people.