NMDA Receptor Modulation for Hyperarousal in PTSD

Purpose: The purpose of this study is to determine whether lanicemine works in the brain in areas believed to be important in post traumatic stress disorder (PTSD). In this study, we will compare lanicemine to a placebo, a saline solution that looks like lanicemine but contains no medication. Placebos are used in research studies to see if the results are due to the study drug or other reasons. Whether you receive lanicemine or placebo is determined by randomization, similar to the roll of a die or toss of a coin. You will have an equal chance (one in two) of being assigned to lanicemine or placebo. This is also a “double-blind” study which means that neither you nor the study staff will know to which treatment you are assigned.

Description: Baylor College of Medicine and the Michael E. DeBakey VA Medical Center are conducting a clinical trial in individuals between the ages of 21-65 to investigate a drug (lanicemine) for the treatment of PTSD. The study is funded by the NIH.

If eligible, participants will receive the study treatments and all study-related care at no cost. Compensation will also be provided for time and travel.

All inquiries are confidential.


Study Coordinator mood@bcm.eduPhone 1: (713) 689-9856
IRB: h-36371




Oct 23, 2018