Research News from IDDRC Investigators

No bioinformatics experience required to use new CRISPR data analytical tool
Posted: April 30, 2019
From the labs of: Huda Zoghbi, M.D. and Zhandong Liu, Ph.D.

Image of the Month: Art meets science to visualize the fruit fly’s brain
Posted: April 2, 2019
From the lab of: Hugo Bellen, DVM, Ph.D.

17p11.2 syndromes are much more than deletions and duplications
Posted: March 26, 2019
From the lab of: James Lupski, M.D., Ph.D. 

Understanding the cell waste disposal problems in Lou Gehrig’s disease
Posted: March 12, 2019
From the lab of: Hugo Bellen, DVM, Ph.D.

SHANK3: the good, the bad and the hopeful
Posted: March 3, 2019
From the lab of: Huda Zoghbi, M.D.

Tuberous sclerosis: it’s not all about mTORC1
Posted: Feb. 28, 2019
From the lab of: Marco Sardiello, Ph.D. 

Image of the Month: Neurogenesis in the adult mouse brain
Posted: Feb. 5, 2019
From the lab of: Benjamin R. Arenkiel, Ph.D.

Solving the mystery of CLN8’s connection with Batten disease
Posted: Jan. 24, 2019
From the lab of: Marco Sardiello, Ph.D. 

Connecting Zika virus and hereditary microcephaly
Posted: Jan. 17, 2019
From the lab of: Hugo Bellen, DVM, Ph.D.

Putting mind and heart together opens a window into the adult brain
Posted: Jan. 10, 2019
From the lab of: Benjamin R. Arenkiel, Ph.D. and James F. Martin, M.D., Ph.D.

The power of the microbiome: A microbe-based treatment reverses social deficits in mouse models of autism
Posted: Dec. 13, 2018
From the lab of: Mauro Costa-Mattioli, Ph.D.

Connecting mTOR and Src, two major players in cancer growth
Posted: Nov. 27, 2018
From the lab of: Marco Sardiello, Ph.D.

Research reveals defective transport of lysosomal enzymes causes a type of Batten disease
Posted: Nov. 7, 2018
From the lab of: Marco Sardiello, Ph.D.

INSiGHT into neuronal fate in the retina
Posted: Oct. 23, 2018
From the lab of: Melanie Samuel, Ph.D.

Connecting Tau aggregates, transposable elements and neurodegeneration in Alzheimer’s disease
Posted: Sept. 9, 2018
From the lab of: Joshua Shulman, M.D., Ph.D.

Thinking outside the box to fight back neurodegeneration
Posted: Aug. 28, 2018
From the lab of: Marco Sardiello, Ph.D.

Pay attention to the ‘noise’ in your brain
Posted: Aug. 23, 2018
From the lab of: Andreas Tolias, Ph.D.

Revealing unique features of the ‘antennae’ on light-sensing neurons
Posted: Aug. 21, 2018
From the laboratory of: Rui Chen, Ph.D.

The Hippo pathway: tailor of the developing heart
Posted: July 5, 2018
From the lab of: James Martin, M.D., Ph.D.

Sorting out what drives Huntington’s disease
Posted: July 12, 2018
From the lab of: Juan Botas, Ph.D.

Of fruit flies, genes and aortic aneurysms
Posted: June 21, 2018
From the lab of: Hugo Bellen, DVM, Ph.D.

Fruit flies: ‘living test tubes’ to rapidly screen potential disease-causing human genes
Posted: May 22, 2018
From the lab of: Shinya Yamamoto, DVM, Ph.D.

Two is better than one, to improve brain function on a mouse model of Alzheimer’s disease
Posted: April 24, 2018
From the lab of: Joanna Jankowsky, Ph.D.

When protein regulators go awry, neurological disease may follow
Posted: April 19, 2018
From the lab of: Huda Zoghbi, M.D.