Mechanisms of Perceptual Learning in Primary Visual Cortex
Study the basic mechanisms of Learning, Perceptual Inference and Decision Making in mouse and monkey animal systems. Our work spans multiple levels of analysis from singe neurons to circuits. We use multi-electrode recordings and in vivo two-photon imaging in awake, behaving animals. We are also interested to study animal models of diseases in mice and use molecular tools to manipulate genes both in mice and primates. To this end, we are interested to use siRNAs in primates.
Relevance of the project to IDDRC mission:
Deficits in learning and intelligence are basic features of mental retardation. My research focuses in understand the mechanisms of learning and inference. Inference is basically the ability to make useful predictions about the environment under novel instances and is the hallmark of intelligence. We are studying these mechanisms in a number of decision making tasks both in the adult and during development (mouse). We are interested to extend our studies in animal models of diseases.