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Diabetes Center

Houston, Texas

The Diabetes and Endocrinology Research Center at BCM is located in the Margaret M. Alkek Building for Biomedical Research
Diabetes and Endocrinology Research Center
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Pilot and Feasibility Program

Dr. Lawrence Chan at the entrance of the Diabetes Research Center

Dr. Lawrence Chan, DRC director, is also the director of the Pilot/Feasibility Program. This program provides support for three types of investigators:

  1. New investigators initiating projects in a diabetes-related area who have no prior independent NIH or other federal funding
  2. Established investigators in diabetes-related research who wish to pursue an innovative or high-risk high-impact project in diabetes
  3. Established investigators in a nondiabetes research area who propose P/F projects in a diabetes-related area

The DRC provides up to $50,000 per year and services of the core laboratories to each project selected for funding. Each P/F project is funded for up to two years, pending satisfactory progress at the end of the first year. After a call for applications is issued, applicants must submit the NIH PHS 398 form.

Pilot and Feasibiity Program Investigators
Year Name Department P&F Application Title Type of P&F Research
(2008-2012) P&F Awardee's Name (Last Name, First Name) at time of P&F award Basic, Clinical, Translational [may use more than one term]
2008-2009 Yechoor, Vijay Medicine Engineering Autoimmune-resistant Lslet Neogenesis to Cure Type 1 Diabetes in NOD Mice Basic diabetes
2008-2009 Dickinson, Mary Molecular Physiology Cellular and Molecular Targets of Diabetic Embryopathy Basic diabetes
2008-2009 Lumpkin, Ellen Neuroscience The role of sensory innervation in healthy and diabetic pancreas Basic diabetes
2009-2010 Pautler, Robia Molecular Physiology Radical Scavenging Carbon Materials as a Diabetes Treatment Basic diabetes
2009-2010 Wehrens, Xander Molecular Physiology Role of CaMKII Phosphorylation of Ryanodine Receptor Type 2 in Insulin Secretion Basic diabetes
2009-2010 Zhang, Pumin Molecular Physiology Functional Dissection of the Role of FTO in the Control of Body Weight Basic diabetes
2009-2010 Yechoor, Vijay Medicine Disruption of the Circadian Molecular Clock Leads to β-cell Failure and Diabetes Basic diabetes
2010-2011 Balyle, Joseph Molecular Physiology Evasion of the CTL and NK Cell Response to Transplanted Pancreatic Islets Basic diabetes
2010-2011 Hommel, Jonathan Pharmacology Neuromedin U as an Innovative Target to Treat Metabolic Diseases Basic diabetes
2010-2011 Samson, Susan Medicine Signaling and Transcription Factor 7-like 2 in the Beta Cell Basic diabetes
2010-2011 Sun, Yuxiang Pediatrics Ghrelin Receptor in Obesity and Insulin Resistance during Aging Basic diabetes
2010-2011 Xu, Yong Pediatrics Mechanisms for Estrogenic Regulation of Glucose Balance Basic diabetes
2011-2012 Mitsiades, Nicholas Medicine Targeting The Contribution Of The Metabolic Syndrome In Cancer Progression: A Pilot Interventional Study Using Metformin And Simvastatin Clinical diabetes
2011-2012 Feng, Qin Molecular Cell Biology Suppression of hepatic PPARα function by CARM1 Basic diabetes
2011-2012 Li, Xiaotao Molecular Cell Biology REGγdeficiency protects against adiposity and improves insulin sensitivity in mice Basic diabetes
2012-2013 Sahin, Ergun Huffington Center On Aging Role of Sirtunins in telomere-mediated metabolic disease
2012-2013 Chen, Wenhao Medicine Therapeutic potential of IL-21 blockade: reversal of overt type 1 diabetes in NOD mice by abrogating the persistent T-cell response to islets
2012-2013 Hu, Zhaoyong Medinie Low Irisin leads to obesity and insulin resistance in mice with muscle-specific ROCK1 activation
2012-2013 Hartig, Sean Molecular Cell Biology A Novel Axis Regulates Adipocyte Plasticity
2012-2013 Borowiak, Malgorzata Ctr Stem Cell & Regen Microenviroment in expansion and maturation of pluripotent stem cell derived human pancreatic progenitors

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