Diabetes Research Center
The Diabetes Research Center at Baylor College of Medicine is part of an integrated program for diabetes and related endocrinology and metabolism research overseen by the National Institute of Diabetes and Digestive and Kidney Diseases. Information on all ongoing NIDDK Diabetes Research Centers can be found at www.diabetescenters.org.
The center's goal is support and facilitate innovative research towards the elucidation of the pathogenesis of diabetes mellitus and the pathphysiologic basis of diabeticcomplications, development of new treatments and the implementation of translational research in diverse diabetes populations.
While the administrative team is housed in the Margaret M. Alkek Building for Biomedical Research, the BCM Diabetes Research Center serves biomedical research in all BCM departments and centers.
- The DRC has 92 investigators in its Biomedical Research Base, whose research interest and expertise can be broadly categorized into four interrelated focus areas.
- It provides support via seven Biomedical Research Cores.
- It presents enrichment opportunities via meetings and seminars.
- It offers a Pilot and Feasibility Program.
Mouse Metabolism Core
Dr. Pradip Saha heads the Mouse Metabolism Core for the Diabetes Research Center. The XF24 from Seahorse Bio service is open to all DRC investigators and BCM investigators who perform diabetes/endocrinology/metabolism research.
Cellular oxygen consumption and glycolysis monitoring using extracellular flux analyzer (XF24) from Seahorse Bio: Measure mitochondrial respiration in intact skeletal muscle fibers, Fatty Acid Oxidation in C2C12 myocytes, glycolysis and oxidative metabolism in cancer cells, understand the relationship between bioenergetic rates, ATP turnover and more.