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CNRC - Xu Lab

Houston, Texas

BCM faculty, staff and trainees are the heart of the organization.
CNRC - Xu Lab
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Principal Investigator

Hui Mei, Ph.D.

Yong Xu, M.D., Ph.D.

Department and Interdepartmental Affiliations

Pediatrics- Nutrition Department
Cellular and Molecular Biology (CMB) Program

Translational Biology and Molecular Medicine Program
Molecular and Cell Biology


BA Medicine, Tongi Medical University 1999
MS Internal Medicine, Tongi Medical University 2002
Ph.D. Cell Biology, University of Alberta 2006
Post-doc, Neuroendocrinology, University of Texas Southwestern 2009
Instructor, Neuroendocrinology, University of Texas Southwestern 2010

Awards & Honors

  • 1994-1999 Excellent Student Scholarships, Tongji Medical College
  • 1995-1998 Federal General Scholarships, Federal Pharmaceutic Inc.
  • 1999 Outstanding Graduate Award, Tongji Medical College
  • 2000 Excellent Student Cadre Awards, Tongji Medical College
  • 2000, 2001 Excellent Graduate Scholarships, Tongji Medical College
  • 2002 Outstanding Graduate Award, Tongji Medical College
  • 2003 Canadian Association for Neuroscience Travel Award
  • 2003 J Gordin Kaplan Graduate Student Travel Award, University of Alberta
  • 2003-2004 FS Chia Ph. D. Scholarship, University of Alberta
  • 2005 75th Anniversary Award, University of Alberta
  • 2005 Andrew Stewart Memorial Graduate Prize, University of Alberta
  • 2005-2007 Izaak Walton Killam Memorial Scholarship, Killam Trustee
  • 2005-2006 Doctoral Research Award, Heart and Stoke Foundation of Canada
  • 2006 Young Investigator Forum Travel Award, Canadian Institute of Health Research
  • 2007-2009 Postdoctoral Research Award, Canadian Institute of Health Research
  • 2009-2013 NIH Pathway to Independence Award (K99/R00)
  • 2011 DERC Pilot & Feasibility Project Grant (P30)
  • 2011-2014 American Diabetes Association Basic Science Award
  • 2011-2015 American Heart Association National Scientist Development Grant (declined)
  • 2011-2012 Naman Family Fund for Basic Research
  • 2011-2012 Curtis Hankamer Basic Research Fund
  • 2011-2016 NIH (R01)
  • 2012-2014 Klarman Family Foundation for Eating Disorders

Books & Book Chapters

Xu Y and Clegg DJ. Brain Estrogens and Metabolism. In “Environment and breast Cancer”.

Corresponding Author Publications

  1. Zhu L, Yang Y, Xu P, Zou F, Yan X, Liao L, Xu J, O’Malley BW, Xu Y. Steroid receptor co-activator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology 2012 (in press).
  2. Tong Q and Xu Y. Central Leptin Regulation of Obesity and Fertility. Current Obesity Reports 2012 (in press).
  3. Xu Y (corresponding author), Faulkner LD and Hill JW. Cross-talk between metabolism and reproduction: The Role of POMC and SF-1 Neurons. Frontiers in Systems and Translational Endocrinology 2012 Jan 4; 2: 1-13.

Hypertension Publications

  1. Xu Y and Krukoff TL. Adrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases. Molecular Pharmacology. 2007 Jul;72(1):112-20. PMID: 17446268.
  2. Xu Y and Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate: a role for protein kinase A. British Journal of Pharmacology. 2006 May;148(1):70-7. PMID: 16501581.
  3. Xu Y and Krukoff TL. Adrenomedullin stimulates nitric oxide release from SK-N-SH human neuroblastoma cells by modulating intracellular calcium mobilization. Endocrinology. 2005 May;146(5):2295-305. PMID: 15677761.
  4. Xu Y and Krukoff TL. Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: roles of glutamate and nitric oxide. American Journal of Physiology- Regulatory, Integrative and Comparative Physiology. 2004 Oct;287(4):R729-34. PMID: 15178541.
  5. Xu Y and Krukoff TL. Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus of is mediated by nitric oxide and GABA. Regulatory Peptides 119: 21-30, 2004. PMID: 15093693.
  6. Additional Publications
  7. Xu Y, Zhou L, Qian W, Xie X and Hou X. Relationship between the expression of calcitonin gene-related peptide and gastrohypersensitivity in non-ulcer dyspepsia patients. Chinese Journal of Digestive Diseases 23(5): 285-288, 2003.
  8. Xu Y. Choice of disinfectors for endoscopes. Chinese Journal of Endoscopy 8(7): 28-30, 2002.
  9. Xu Y and Hou X. Orphanin FQ and gastrointestinal motility. Foreign Medical Sciences 22(1):14-16, 2002.

Baylor Recognition