Final Report

The spine in focus.
From the OPUS Wrap-Up Meeting, September 6, 2006

The 2-year follow-up, multi-center OPUS soy isoflavone study was completed in June, 2006 with 406 women enrolled in the study. The Experimental Biology 2006 minisymposium, Soy and Potential Health Benefits, co-chaired by Drs. William Wong and Richard Lewis, received a total of 23 abstracts. Our annual OPUS team meeting, co-chaired by Ms. Karen Konzelmann and Dr. William Wong, was held on April 3, 2006 in San Francisco, California.

The meeting was attended by Drs. Susan Welsh and Etta Saltos of CSREES/USDA. An OPUS Wrap-up Meeting was held on September 6, 2006 in Houston, Texas. There the team finalized plans for data analyses, publications, writing assignments, and publication timelines. An R03 grant application, Soy Isoflavone Supplementation and Mammographic Density in Postmenopausal Women, submitted by the team and Dr. Gertruad Maskarinec from the Cancer Research Center of Hawaii, was selected for funding by the NIH/NCI.

This successful collaboration was a result of our invitation of the EB minisymposium speakers to our annual team meetings. In terms of education and extension: Drs. Sharon Robinson and Mary Bielamowicz of Texas Cooperative Extension (TCE) at Texas A&M University (TAMU) developed an education kit, Standing On Your Own: Osteoporosis and the Benefits of Soy Foods.

The kit, which targets adults and teens, is available online through the TCE bookstore: - item #B-6174.

The adult curriculum is available online through the TCE website:

In November 2005, Drs. Robinson and Bielamowicz conducted five concurrent workshops and trained ~350 county agents in Family and Consumer Sciences and EFNEP and FSNEP staff with the education kit.

In August 2006, Dr. Robinson trained 50 teachers at Houston DeBakey High School for Health Professionals. The education kit was disseminated to Extension Food and Nutrition Specialists in 50 states. Dr. Sharon Robinson presented a poster, Focus Groups with Texas Women Indicates Lack of Awareness of Osteoporosis Risk Factors, at the American Dietetic Association annual meeting in October, 2005.

Dr. William Wong presented the project, Effect of Soy Isoflavones on Osteoporosis in Postmenopausal Women, at the North American Research Conference on Complementary and Integrative Medicine in Edmonton, Canada on May 27, 2006.

Dr. Paula Amato, presented an abstract, Effect of Soy Isoflavone Supplementation on Serum Lipids in Postmenopausal Women, at the Endocrine Society 88th Annual Meeting, June 24-27, 2006 in Boston, MA.

Dr. William Wong has been invited to present, Soy and Women’s Health, at the TAMU 34th Annual Nutrition Conference in February, 2007 with an expected attendance of ~ 300 researchers, students, and county Extension agents.

For the 4th year, the team will chair a minisymposium, Soy and Potential Health Benefits, during the 2007 Experimental Biology meeting in Washington, DC. The OPUS website,, has educational resources and will include study results as they become available.

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