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CNRC - Mouse Metabolic Research Unit

Houston, Texas

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CNRC - Mouse Metabolic Research Unit
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Use the MMRU

Step 1. Pricing (per mouse)

Simultaneous indirect calorimetry, food mass monitoring plus access control, and physical activity monitoring w/ or w/o running wheels. $18 per day
Simultaneous indirect calorimetry, food mass monitoring plus access control, physical activity, and core body temperature monitoring. $19 per day
Simultaneous food mass monitoring plus access control $9 per day
Treadmill use with calorimetry $40 set-up + $8/hr
6-Lane Treadmill $8/hr
PIXImus or QMR body composition measurements $2.50 per mouse

Note: To keep costs down, MMRU requests its users perform some setup and takedown tasks for experiments. Read the complete list of Investigator and MMRU responsibilities »

Step 2. Check MMRU availability

Use the MMRU calendar via Outlook calendar:

  1. In Outlook, click "Folder List" at the bottom left of the Outlook screen.
  2. Click the + before "Public Folders" then click the + before "All Public Folders."
  3. Scroll down to "BCM Pediatrics," then inside to "Nutrition."
  4. Click the Calendar named "MMRU Schedule."
  5. To add to favorites, right-click "MMRU Schedule" and then select "Add to Favorites."
  6. Click "Calendar" (beside "Folder List" at the bottom left of the Outlook screen).

Step 3. Read and Understand Investigator and MMRU responsibilities

Investigator responsibilities

  • Obtain the appropriate institutional approvals for MMRU (e.g., IACUC protocol, IBC protocol). For reference, the MMRU IACUC protocol number is AN-5020.
  • For mice not currently housed within the CNRF, investigator must organize the transfer as discussed in "Procedure for Requesting Use of Facilities."
  • Investigator, investigtor's staff or students must be in the CNRF at 8:30 a.m. on the days when experiments start and finish, unless otherwise instructed by Firoz Vohra.
  • Provide mice with the correct diet (in a powdered form) in accordance with an approved IACUC protocol. Check for sufficient food in the feeders at least every other day.
  • Provide mice with water; check water at the same time as food.
  • For long-term studies, cages and water must be changed a minimum of once every 5 days.
  • Implantation of telemetric devices (training provided by MMRU upon request).
  • Provide Firoz Vohra an Excel spreadsheet with the IDs, genotype, diet, sex, and date-of-birth of the mice, and beginning body weight, prior to placement within CLAMS cages.
  • Decide whether acclimatization of mice within the CLAMS cages is performed prior to data measurements (an acclimatization period of 2-3 days is strongly recommended).
  • Check Temperature and humidity of the room in which your mice are housed and enter the values in the individual room's log book. This is a BCM requirement and must be done daily, including weekends.
  • Clean treadmill and QMR mouse holders after every use.
  • Empty all feed from feeders at the end of studies.

MMRU responsibilities

  • Supply, cleaning, and preparation of CLAMS cages
  • Calibration and programming of monitoring devices
  • Provision of conditions conducive to generation of high caliber data
  • Aid in data handling and interpretation

Step 4. Select instrument to reserve