Venezia by PVII

Paul Nakata, Ph.D.Paul Nakata, Ph.D.

Assistant Professor of Pediatrics
Baylor College of Medicine
Plant Biologist, Agricultural Research Service
US Department of Agriculture

Nutrient partitioning in plants and its manipulation for nutritional improvements of plant foods

My primary research interest is in elucidating the mechanisms regulating nutrient partitioning in plants and the manipulation of these mechanisms for nutritional improvement of plant foods. Current focus is to understand the mechanisms regulating calcium partitioning and sequestration in plants. To accomplish this goal, we are taking and integrated biochemical, cellular, molecular, and genetic approach to identify and characterize the components regulating calcium transport and storage. Such studies may lead to the rational design of strategies to enhance calcium abundance and bioavailability in plant foods.

Representative publications:

Morris, J, Nakata, PA, McConn, MM, Brock, A and Hirschi, KD (2007). Increased calcium bioavailability in mice fed genetically engineered plants lacking calcium oxalate. Plant Molecular Biology. 64:613-618.

Nakata, PA and McConn, MM (2007). Genetic evidence for differences in the pathways of druse and prismatic calcium oxalate crystal formation in Medicago truncatula. Functional Plant Biol. 34:332-338.

Nakata, PA and McConn, MM (2007). Calcium oxalate content affects the nutritional availability of calcium from Medicago truncatula leaves. Plant Science. 172:958-961.

Nakata, PA and McConn, MM (2007). Isolated Medicago truncatula mutants with increased calcium oxalate crystal accumulation have decreased ascorbic acid levels. Plant Physiology and Biochemistry. 45:216-220.

Nakata, PA and McConn, MM (2006). A genetic mutation that reduces calcium oxalate content increases calcium availability in Medicago truncatula. Functional Plant Biol. 33:703-706.

Korth, KL, Doege, SJ, Park, S-H, Goggin, FL, Wang, Q, Gomez, SK, Liu, G, Jia, L, Nakata, PA (2006). Medicago truncatula mutants demonstrate the role of plant calcium oxalate crystals as an effective defense against chewing insects. Plant Physiol. 141:188-195.

Franceschi, VR and Nakata, PA (2005). Calcium oxalate in plants: Formation and function. Annu. Rev. Plant Biol. 56:41-71.

McConn, MM and Nakata, PA (2004). Oxalate reduces calcium availability in the pads of the prickly pear cactus through formation of calcium oxalate crystals.  J. Agric. and Food Chem. 52:1371-1374.

Kostman, TA, Franceschi, VR, and Nakata, PA (2003). Endoplasmic reticulum sub-compartments are involved in calcium sequestration within raphide crystal idioblasts of Pistia stratiotes, L. Plant Science 165:205-212. .

Nakata, PA (2003). Advances in our understanding of calcium oxalate crystal formation and function in plants. Plant Science 164:901-909.

Nakata, PA, Kostman, TA, and Franceschi, VR (2003). Calreticulin is enriched in the crystal idioblasts of Pistia stratiotes. Plant Physiol. and Biochem. 41:425-430.

Nakata, PA and McConn, MM (2003). Calcium oxalate crystal formation is not essential for growth of Medicago truncatula. Plant Physiol. and Biochem. 41:325-329.

Nakata, PA and McConn, MM (2003). Influence of the calcium oxalate defective 4 (cod4) mutation on the growth, oxalate, and calcium content of Medicago truncatula. Plant Science 164:617-621.

Nakata, PA and McConn, MM (2002). Sequential subtractive approach facilitates identification of differentially expressed genes. Plant Physiol. and Biochem. 40:307-312.

Nakata, PA (2002). The generation of a transposon-mutagenized Burkeholderia glumae library to isolate novel mutants. Plant Science 162:267-271.

McConn, MM and Nakata, PA (2002). Calcium oxalate crystal morphology mutants from Medicago truncatula. Planta 215:380-386.

Nakata, PA (2002). Calcium oxalate crystal morphology. Trends in Plant Science 7:324.

Nakata and McConn. Isolation of Medicago truncatula mutants defective in calcium oxalate formation. Plant Physiol, 2000; 124:1097-1104.


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