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CNRC - Davis Lab

Houston, Texas

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CNRC - Teresa Davis Lab
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Renán Orellana, M.D.

Renán Orellana, M.D.

Assistant Professor of Pediatrics, Baylor College of Medicine

Section of Critical Care
Department of Pediatrics
Baylor College of Medicine

View Dr. Orellana's bio.

Residency in Pediatrics: Nassau County Medical Center, 2000
Post-Doctoral Fellow, USDA/ARS Children’s Nutrition Research Center at Baylor College of Medicine, 2003
Pediatric Critical Care Fellowship: Baylor College of Medicine, 2004
Medical Doctorate: Universidad de El Salvador, 2006

Under the mentorship of Dr. Teresa Davis, the long-term objective of Dr. Orellana's research efforts is to alleviate muscle catabolism by specific nutritional and pharmacological interventions to support critically ill infants and children at different stages of development so as to decrease morbidity and improve recovery from critical illness. By using a pig model of critical illness, Orellana is examining the effects of sepsis and mechanical ventilation on the mechanisms that limit diaphragm and skeletal muscle protein deposition and accelerate muscle catabolism in pediatric patients, and the impact of maturation on these physiological events.

Agus Suryawan, Ph.D.Agus Suryawan, Ph.D.

Instructor of Pediatrics, USDA/ARS Children’s Nutrition Research Center, Baylor College of Medicine

View Dr. Suryawan's bio.

B.S. (Animal Science) Padjadjaran University, Indonesia, 1984
M.S. (Animal Science) Oregon State University, 1990
Ph.D. (Animal Science) Oregon State University, 1995
Research Fellow, Wake Forest School of Medicine, 1999
Postdoctoral Fellow, USDA/ARS Children’s Nutrition Research Center, Baylor College of Medicine, 2003

Dr. Suryanwan's main interest is the molecular mechanism by which insulin and amino acids regulate skeletal muscle protein synthesis and degradation. The majority of the information regarding protein synthesis and degradation has been generated from cell culture studies. However, less is known about the molecular mechanisms that regulate protein synthesis/degradation in whole animals or in vivo. Thus, the elucidation of molecular mechanisms controlling these major metabolic processes will allow us to formulate interventions that can improve skeletal muscle growth during the neonatal period.

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