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CNRC - Abrams Lab

Houston, Texas

Images depicting the Abram lab's research work
Steven Abrams' Micronutrient Research Lab
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Abrams SA, Hawthorne KM. Bone Health in Children. CRC Press, Boca Raton, Florida, 2012.

Bone health is one of the most widely discussed topics in pediatric nutrition. Ensuring adequate calcium and vitamin D intake is essential, and other factors also play a significant role. Bone Health in Children explores the recent decades of research and public commentary on the subject, debunks popular myths, and clarifies the often confusing and contradictory scientific literature. Presenting practical and theoretical education and advice, the book provides rational and accessible information geared to a wide audience of individuals interested in this critical element of pediatric health.

Highlights include:

  • The Institute of Medicine process by which Dietary Reference Intakes (DRIs) are developed
  • Iron, calcium, and vitamin D requirements for infants, children, & pregnant and lactating women
  • Controversy over high-dose vitamin D supplementation and pregnancy
  • Detailed explanation of the scientific research process related to human nutrition
  • The non-bone health aspects of vitamin D & why literature claims about this topic can be misleading
  • Frequently Asked Questions regarding nutrition with answers in short format

Abrams SA, Wong WW, eds. Stable isotopes in Nutrition. CABI Publishing, Oxon, UK 2003

Journal Articlies

Abrams SA, Copeland KC, Gunn SK, Gundberg CM, Klein KO, Ellis KJ. Calcium absorption, bone accretion and kinetics increase during early pubertal development in girls. J Clin Endocrinol Metab 2000;85:1805-1808. Abstract : : Full text html

Griffin IJ, Davila PM, Abrams SA. Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes. Br J Nutr 2002;87:S187-S191 Abstract: : Full text html : : Full text pdf

Abrams SA, Griffin IJ, Davila PM. Calcium and zinc absorption from lactose-containing and lactose-free infant formulas. Am J Clin Nutr. 2002;76:442-6. Abstract : : Full text html

Domellöf, M, Bo Lönnerdal B, Abrams SA, Hernell O. Iron absorption in breast-fed infants:Effect of age, iron status, iron supplements and complementary foods. Am J Clin Nutr 2002;76:198-204.
Abstract: : Full text html

Herman S, Griffin IJ, Suwarti S, Ernawati F, Permaesih D, Pambudi D, Abrams SA. Co-fortification of iron fortified flour with zinc sulfate, but not zinc oxide, decreases iron absorption in Indonesian children Am J Clin Nutr 2002;76:813-817. Abstract : : Full text html

Olivares M, Lonnerdal B, Abrams SA, Pizarro F, Uauy. Effects of age and copper intake on copper absorption in young infants measured using 65Cu as a tracer Am J Clin Nutr 2002;76:641-645.
Abstract : : Full text html

Abrams SA, Griffin IJ, Herman S. Using stable isotopes to assess the bioavailability of minerals in food-fortification programs. Food Nutr Bull 2002:23:158-165. Abstract

Zavaleta N, O'Brien KO, Abrams SA, Caulfield LE Maternal iron status influences iron transfer to the fetus during the third trimester of pregnancy. Am J Clin Nutr 2003;77:924-30. Abstract : : Full text html

Diaz M, Rosado JL, Garcia PA, Abrams SA, Allen LH. The efficacy of a local ascorbic acid-rich food to improve iron absorption from Mexican diets: a field study using stable isotopes. Am J Clin Nutr 2003 (In Press).

Abrams SA, Mushi A, Hilmers DC, Griffin IJ, Davila P, Allen A. A multi-nutrient-fortified beverage enhances the nutritional status of children in Botswana. J Nutr 2003 (In Press).

Shah, M, Griffin IJ, Lifschitz CF, Abrams SA. Effect of orange and apple juices on iron absorption in children. Arch Pediatr Adol Medicine 2003 (In Press).

Abrams, S. A., Griffin, I. J., Hawthorne, K. M., Liang, L. Height and Height Z-Score Are Related to Calcium Absorption in Five- to Fifteen-Year-Old Girls J Clin Endocrinol Metab 2005 90: p. 5077-5081

Avalos Mishaan AM, Zavaleta N, Griffin IJ, Hilmers DC, Hawthorne KM, Abrams SA. Bioavailability of iron and zinc from a multiple micronutrient-fortified beverage. Journal of Pediatrics 2004 Jul;145(1):26-31.

Etcheverry P, Hawthorne KM, Abrams SA, Griffin IJ. Beef protein increases iron and zinc absorption compared to soy protein. Pediatr Res 2004;55:180A.

Abrams SA, Weaver CM, McCabe GP, Griffin IJ, Hilmers DC, Hawthorne KM, Martin BR, McCabe LD, Ellis KJ. Calcium absorption is related to growth during puberty. Pediatr Res 2004;55:181A.

Hawthorne KM, Griffin IJ, Ellis KJ, Abrams SA. Soft drink intake is not related to phosphorus intake or bone density. Journal of the American Dietetic Association, August 2004, Suppl 2 ­ Abstracts; Vol 104, Number 8, A-50.

Hawthorne KM, Griffin IJ, Abrams SA. Current issues in nutritional management of very low birth weight infants. Minerva Pediatrica 2004 Aug; 56(4): 359-72.

Hawthorne KM and Abrams SA. Safety and efficacy of human milk fortification for very-low-birth-weight infants. Nutrition Reviews Dec 2004;62(12):482-485.

Abrams SA, Griffin IJ, Hawthorne KM, Zhensheng C, Gunn SK, Wilde M, Darlington G, Shypailo R, Ellis K. Vitamin D receptor fok1 polymorphisms affect calcium absorption, kinetics, and bone mineralization rates during puberty. J Bone Min Res. 2005 Jun;20(6):945-953.

Abrams SA, Griffin IJ, Hawthorne KM, Gunn SK, Gundberg CM, Carpenter TO. Relationships among vitamin D levels, PTH, and calcium absorption in young adolescents. J Clin Endocrinol Metab published August 2, 2005 as doi:10.1210/jc.2005-1021.

Etcheverry, P, Hawthorne KM, Liang LK, Abrams SA, Griffin IJ. Effect of beef and soy proteins on the absorption of non-heme iron and inorganic zinc in children. Journal of the American College of Nutrition 2006; 1:34-40.

Hawthorne KM, Moreland K, Griffin IJ, Abrams SA. An educational program enhances food label understanding of young adolescents. J Am Diet Assoc 2006; 106:913-916.

Etcheverry P, Carstens GE, Brown E, Hawthorne KM, Chen Z, Griffin IJ. Production of stable-isotope-labeled bovine heme and its use to measure heme-iron absorption in children. Am J Clin Nutr 2007;85:452-9.

Lynch MF, Griffin IJ, Hawthorne KM, Chen Z, Hamzo MG, Abrams SA. Calcium balance in 1-4-y-old children. Am J Clin Nutr 2007;85:750-4.

Lynch MF, Griffin IJ, Hawthorne KM, Chen Z, Hamzo MG, Abrams SA. Iron absorption is more closely related to iron status than to daily iron intake in 12- to 48-mo-old children. J Nutr 2007;137:88-92.

Griffin IJ, Lynch MF, Hawthorne KM, Chen Z, Hamzo MG, Abrams SA. Zinc homeostasis in 1-4 year olds consuming diets typical of US children. Brit J Nutr 2007;98:358-63.

Hawthorne KM, Abrams SA, Weird WC. Plasma phospholipid levels in children improve with supplementation of DHA to orange juice. J Am Diet Assoc 2007;107:8,A-56.

Abrams SA, Griffin IJ, Hawthorne KM, Ellis KJ. Effect of prebiotic supplementation and calcium intake on body mass index. J Pediatr 2007;151:293-8.

Abrams SA, Hawthorne KM, Aliu O, Hicks PD, Chen Z, Griffin IJ. An inulin-type fructan enhances calcium absorption primarily via an effect on colonic absorption in humans. J Nutr 2007;137:2208-12.

Griffin IJ, Lynch MF, Hawthorne KM, Chen Z, Hamzo M, Abrams SA. Magnesium retention in 12 to 48 month-old children. JACN 2008;27:349-355.

Morris J, Hawthorne KM, Hotze T, Abrams SA, Hirschi KD. Nutritional impact of elevated calcium transport activity in children. Proc Natl Acad Sci USA 2008; Feb 5;105(5): 1431-5.

Hawthorne KM, Morris J, Hotze T, Hirschi KD, Abrams SA. Biotechnologically-modified carrots: calcium absorption relative to milk. J Bioequivalence Bioavailability 2009, 1:034-038. doi: 10.4172/jbb.1000006.

Mitchell SM, Rogers SP, Hicks PD, Hawthorne KM, Parker BR, Abrams SA. High frequencies of elevated alkaline phosphatase activity and rickets exist in extremely low birth weight infants despite current nutritional support. BMC Pediatr 2009; Jul 29;9:47.

Balay KS, Hawthorne KM, Hicks PD, Griffin IJ, Chen Z, Westerman M, Abrams SA. Orange but not apple juice enhances ferrous fumarate absorption in small children. JPGN 2009;49.

Abrams SA, Hicks PD, Hawthorne KM. Higher serum 25-hydroxyvitamin D levels in school-age children are inconsistently associated with increased calcium absorption. J Clin Endocrinol Metab 2009; 94:2421-2427.

Willis T, Carter B, Rogers S, Hawthorne KM, Hicks PD, Abrams SA. High rates of mortality and morbidity occur in infants with parenteral nutrition-associated cholestasis. JPEN 2010;34:32-37.

Abrams SA, Hawthorne KM, Rogers SP, Hicks PD, Carpenter TO. Effects of ethnicity and vitamin D supplementation on vitamin D status and changes in bone mineral content in infants. BMC Pediatrics 2012; 12:6.

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