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Dan L. Duncan Cancer Center

Houston, Texas

BCM has 25 departments and more than 90 research and patient-care centers.
Dan L. Duncan Cancer Center
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Biostatistics and Informatics Shared Resource

Mission

The primary purpose of the biostatistics and informatics shared resource is to support the research efforts of Dan L. Duncan Cancer Center investigators through collaboration on biostatistical and informatic aspects of design, conduct, analysis, and interpretation of clinical, translational and basic science studies.

Services

Requests for service are initiated in several ways, but virtually always involve personal contact and discussion. Investigators with an existing collaboration with a resource member should contact the member directly. Investigators with new projects may contact a member or Dr. Hilsenbeck or Dr. Becnel. Projects may also be undertaken at the request of center leadership.

Physical Location

We are located on the 3rd and 4th floors of the Cullen Building and Biomedical Informatics Group is located on the 5th floor of the Jewish Building, Suite 529D.

Susan Hilsenbeck, Ph.D.
One Baylor Plaza
Cullen Building
Room 333A, BCM MS 600
Houston, TX 77030
Tel: 713-798-1632
Fax: 713-798-1642
E-mail: sgh@bcm.edu

Lauren Becnel, Ph.D.
One Baylor Plaza
Jewish Building
Room 529, BCM MS 305
Houston, TX 77030
Tel: 713-798-7490
Fax: 713-798-6822
E-mail: becnel@bcm.edu

The Resource will provide the following services:

Biostatistics, Bioinformatics & Analytics

  • General consultation
  • Grant planning and preparation
  • Experimental design
  • Assistance with conduct of clinical trials
  • Data analysis & interpretation
  • Methodologic development
  • Web based, database & backed applications development
  • Project Management
  • Application Hosting
  • High performance computing
  • Standards-compliant

(WHO, CDISC, NCI Database)

Site Licenses for Scientific Software

SAS, SPSS, Ingenuity, SigmaPlot, Ocnomine Pro

Contact the License Support Group: licensing@breastcenter.tmc.edu

Statistical review for PRMS, DRC, etc.

Reviewer Assignments:

Susan Hilsenbeck, Ph.D. - PRMC Executive Committee, PRMC Adult Working Group, DRC Clinical Research Leadership Committee
Hao Liu, Ph.D. - PRMC CAGT Working Group, Adult DRC, CAGT DRC
Charlotte Ahern, Ph.D. - PRMC Pediatric Working Group, Pediatric DRC
Anna Frolov, M.S. - PRMC Adult Working Group

Education and Training

Course 805-403: Introduction to Biostatistics for Translational Research

This course will introduce biostatistical principles and technology most likely to be useful to laboratory scientists interested in translational research, including ANOVA, linear regression, logistic regression, survival analysis, and nonparametric statistics. The course also introduces basic designs for clinical trials and statistical analysis of genomic data from clinical samples.

Credits: 3 Term: 4 Director: Dr. Susan Hilsenbeck

310-459J Bioinformatics and Genome Analysis

This course is intended to provide a background in the theory and application of standard computational methods for molecular biology research. The topics to be discussed include databases, sequence comparison, phylogeny, pattern inference and matching, RNA secondary structure, and protein structure. The course will also address computational issues for the Human Genome Program in the areas of large-scale DNA sequencing, chromosome mapping, and gene recognition. During the term, a seminar speaker, with expertise in an area relevant to the subject area of the course, is invited as a guest lecturer. Students are required to attend this seminar.

Credits: 3 Term: 4 Director: Dr. Kim Worley Instructors: Dr. Lauren Becnel, Dr. Susan Hilsenbeck

Personnel

Co-Directors

Susan Hilsenbeck, Ph.D.
Professor & Director
Prognostic/predictive factors; early phase clinical trials; genomic analysis
sgh@bcm.edu

Lauren Becnel, Ph.D.
Asst. Professor & Co-Director
Subject matter expert, object modeling, basic biobanking, translational and clinical applications
becnel@bcm.edu

Shared Resource Faculty

Anna Tsimelzon, Ph.D.
Assistant Professor
Microarray analysis
annat@bcm.edu

Chad Creighton, Ph.D.
Associate Professor
Bioinformatics, genomic analysis
creighto@bcm.edu

Chad Shaw, Ph.D.
Assistant Professor
Bioinformatics, genomic analysis
cashaw@bcm.edu

Hao Liu, Ph.D.
Associate Professor
Survival analysis and longitudinal data
haol@bcm.edu

Wei Li, Ph.D.
Associate Professor
Epigenetic and transcriptional regulation in cancer
wl1@bcm.edu

Quincy Mo, Ph.D.
Assistant Professor
Genomic analysis, bioinformatics, clinical trials, general statistical analysis
qmo@bcm.edu

Biostatistics Staff

Anna Frolov, M.S.
Instructor
Prostate cancer, prognostic factors
afrolov@bcm.edu

Eunji Jo, M.S.
Senior Biostatistician
General statistical analysis
ejo@bcm.edu

Meng-Fen Wu, M.S.
Senior Biostatistician
Early clinical trials, general statistical analysis
mengfenw@bcm.edu

Tao Wang, M.S.
Senior Biostatistician
Analysis of clinical trials
taow@bcm.edu

Yiqun Zhang, M.S.
Senior Biostatistician
Genomic analyses, general statistical analysis
yiqunz@bcm.edu

Biomedical Informatics Staff and Trainees

Apollo McOwiti
Lead Bioinformatics Programmer
Software Systems
amcowiti@bcm.edu

Benjamin Pew
Sr. Programmer/Analyst
Java Enterprise Edition applications programming, model-driven design
pew@bcm.edu

Chastity Smith
Active directory, MAC OSX, Desktop Support
cs4@bcm.edu

Dapeng “Paul” Wang, M.D.
Programmer/Analyst
.NET Application Programming, SQL Server, Database developer
dapengw@bcm.edu

Yolanda Darlington, Ph.D.
Postdoctoral Associate
Business Analyst, basic application development, biobanks
darlingt@bcm.edu

Hiedi Dowst
Project Manager
Six Sigma PM, Business Analyst, biobanks application development
dowst@bcm.edu

Jeremy Easton-Marks
Senior Programmer/Analyst
Java Enterprise Edition applications programming, model-driven design, Hbase, Hadoop
eastonma@bcm.edu

Jon Barney
Manager, Technical Project Manager
Project management, systems administration
jbarney@bcm.edu

Michael Dehart
System Administrator
System administration, High performance computing
dehart@bcm.edu

Pamela Mayfield, BS, ACS
Project Manager
Project Management, business, analyst, subject matter expert, clinical research application development
pmayfiel@bcm.edu

Shijing “Jane” Qu, MS
Database Administrator
Oracle, MySQL, Database Administration, Data QA/QC
shijingq@bcm.edu

Yingying Sun, MS
Programmer Analyst II
Java Developer
ysun1@bcm.edu

Weimen Wu, Ph.D
Lead Scientific Programmer
Oracle Certified database administrator
weiminw@bcm.edu

Roger Ramirez
Senior, Administrative Coordinator
Administration & Licensing
rogerr@bcm.edu

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