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Dan L. Duncan Cancer Center

Houston, Texas

BCM has 25 departments and more than 90 research and patient-care centers.
Dan L. Duncan Cancer Center
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Mass Spectrometry

(Hon-chiu Eastwood Leung, Ph.D., Director)

Mission and Goals

The Mass Spectrometry-Proteomics Core Laboratory (MS-PCL) of Baylor College of Medicine provides services for high sensitivity high throughput triple Time-of-Flight mass spectrometer and full-fledged proteomics technologies for discovery and validation of biomarkers of various diseases. The services include (i) rapid mass determination of proteins and peptides, (ii) identification of proteins/peptides in complex biological samples, (iii) subproteome isolation and characterization, and (iv) detailed analysis of post-translational modification of proteins/peptides. The MS-PCL is also planning to meet the Good Laboratory Practice.

Services Provided
  • Protein/peptide QC
  • OFFgel liquid phase isoelectric focusing
  • Strong cation exchange liquid chromatography
  • ITRAQ labeling, profiling, and quantitation
  • Depletion of highly abundant proteins in serum/plasma
  • Phosphoproteome enrichment
  • Glycoproteome enrichment
  • 2D gel electrophoresis
  • DIGE labeling and 2D gel electrophoresis
  • Spot cutting and protein identification
  • Accurate mass determination of proteins
  • High-throughput identification of proteins in complex samples
  • Peptide sequencing using tandem mass spectrometry
  • Multiple Reaction Monitoring (MRM) of biological samples
  • Post-translational modification analysis of proteins/peptides
Price List

Mass Spectrometry Price List

Equipment
  • Eksigen nanoLC-Ultra 2D system
  • AB SCIEX TripleTOF 5600 mass spectrometer
  • Agilent OFFgel isoelectric focusing system
  • Agilent 1200 capillary LC system
  • Biotek Synergy 2 plate reader
  • BioRad Versadoc 400MP gel imaging system
Request Form for Services

Mass Spectrometry Request Form

Personnel
Hon-chiu Eastwood Leung, Ph.D.
Assistant Professor
Phone: 713-798-6360
E-mail:Hleung@bcm.edu
Physical Location
Baylor College of Medicine
One Baylor Plaza
1st Floor Jewish Wing 120D
Alkek Center for Molecular Discovery
Houston, TX 77030

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