2012 Journal Club Schedule
Director: Rachel Schiff
|Jan. 3||N315||Xixi Cao -||
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. Nature Medicine 2011. 17:1646-1651.
|Jan. 17||N315||Cancelled due to Think Tank|
|Feb. 7||N315||Kim Holloway||
Histone demethylase JMJD2B coordinates H3K4/H3K9methylation and promotes hormonally responsive breast carcinogenesis. PNAS 2011. 108(18): 7541-7546.
|Feb. 21||N315||Natalie Fernandez||
Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis mediated by Met Signaling Pathway. Cancer Cell 2012. 21:66-81.
|March 6||N317||Wei Wei||A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer. Cell Stem Cell 2012. 10(2):183-97.||Michael Lewis|
|March 20||N317||Liguo Wang||
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell 2011. 147(6): 1408-1419.
|Wei Li (DLDCC)|
|April 17||N317||Cuijuan Yu||
Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State. Cell 2012. 148: 1015-1028.
|May 1||N317||Vidya Sinha||
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop. Nature Medicine 2011. 18: 529-537.
|May 15||N317||Andrew Ciupek||
Stromal ER-alpha promotes tumor growth by normalizing an increased angiogenesis. Cancer Res. 2012. 72(12): 3010-3019.
|Sept. 18||M321||Toyin Babarinde||
Identification of human triple-negative
breast cancer subtypes and preclinical
models for selection of targeted therapies. J Clin Invest. 2011; 121(7): 2750-2767.
|Oct. 2||M423||Sarah Hein||
Comprehensive molecular portraits of
human breast tumours. Nature 2012.
|Oct. 16||M423||Atreyi Dasgupta||
p53 -Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer. Cancer Cell 2012. 21(6): 793-806
|Oct. 30||N315||Teresa Monkkonen||
Activation of Robo1 Signaling of Breast Cancer Cells by Slit2 from Stromal Fibroblast Restrains Tumorigenesis via Blocking PI3K/Akt/ beta-Catenin Pathway. Cancer Res. 2012; 72(18):4652-4661.
|Nov. 13||No Meeting||Cancelled due to DLDCC Symposium|
|Nov. 20||N315||Sabrina Herrera||Prognostic value of proliferation assay in the luminal, HER2 positive and triple negative biological classes of breast cancer. Breast Cancer Research 2012.||Carolina Gutierrez|
|Dec. 4||No Meeting||Cancelled due to SABCS|
|Dec.18||No Meeting||Cancelled due to upcoming Holidays|
Coordinator: Janice Lemmon
Please select key recent papers, mostly those with high relevance to various research fields in cancer and specifically breast cancer. Try to be broad in selecting the papers; it is highly recommended that you do not choose papers with a very close insight to your own direct project. Please consider this point when you select your manuscript and get your mentor’s approval. If you feel that you need my help in selecting a paper, do not hesitate to contact Dr. Rachel Schiff.
This seminar series is also designed to give an opportunity to the trainee to deliver a formal presentation that includes introduction to the topic and a clear presentation of the results, and to lead a discussion of the strengths and weaknesses of the paper. Finally, it is important that all attendees read the paper before the presentation to allow a fruitful discussion.
Two weeks before your day to present: Submit a pdf of the manuscript to Janice Lemmon