2011 Journal Club Schedule
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
PNAS Dec 14, 2010, vol 107 no 50 21737-21742.
|Jan. 18||-||cancelled - due to Think Tank||-||-|
|Feb. 1||N315||Guowei Gu||A microRNA targeting dicer for metastasis control. Cell 141, 1195-1207, June 25, 2010. www.sciencedirect.com/science||Suzanne Fuqua|
|March 1||N315||Vidya Sinha||Identification of aneuploidy-selective antiproliferation compounds. Cell 144(4) Feb 2011. 465-466.||Yi Li|
|March 15||N315||Andrew Ciupek||Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells. Cancer Res 2010;70:4092-4101.||Suzanne Fuqua|
|April 19||N315||Yassine Rechoum||Epigenetic silencing mediated through activated P13K/AKT signaling in breast cancer. Cancer Res 2011; 71(5) Mar 1||Suzanne Fuqua|
|April 26||N315||Yasmine Haddad||Genome remodeling in a basal-like breast cancer metastasis and xenograft. Nature, Vol 464, Apr 2010: 999 - 1005||Suzanne Fuqua|
|May 10||N315||Mario Giuliano||Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nature Medicine, Vol 17 (4) March 2011: 461-470.||Rachel Schiff|
|May 17||N315||Homer Adams||Tumor-Derived jagged1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells.||Michael Lewis|
|Oct. 4||M321||Evelin Young||Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion.||Eric Chang|
|Oct. 18||M321||Mario Giuliano||Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell. 2011; Sept 13;20(3):300-14||Rachel Schiff|
|Nov. 1||N315||Christopher Bland||-Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. 2011; July; 475: 231-234.||Thomas Westbrook|
|Nov. 15||N315||Hugo Villanueva||Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 145; 926-940, June 2011.||Michael Lewis|
|Dec. 20||M321||Jie Dong||-||-|
Please select key recent papers, mostly those with high relevance to various research fields in cancer and specifically breast cancer. Try to be broad in selecting the papers; it is highly recommended that you do not choose papers with a very close insight to your own direct project. Please consider this point when you select your manuscript and get your mentor’s approval. If you feel that you need my help in selecting a paper, do not hesitate to contact Dr. Rachel Schiff.
This seminar series is also designed to give an opportunity to the trainee to deliver a formal presentation that includes introduction to the topic and a clear presentation of the results, and to lead a discussion of the strengths and weaknesses of the paper. Finally, it is important that all attendees read the paper before the presentation to allow a fruitful discussion.