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Lester and Sue Smith Breast Center

Houston, Texas

The Lester and Sue Smith Breast Center's mission is to improve prevention, diagnosis and treatment of breast disease.
Lester & Sue Smith Breast Center
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2009 Journal Club Schedule

Journal Club

1st and 3rd Tuesday each month
Noon, room M323

Pizza is provided

Date Presenter Title Host
Jan. 6 Luca Malorni
Systemic endocrine instigation of indolent tumor growth requires osteopontin Rachel Schiff/
CK Osborne
Jan. 13 Jinfeng Suo
A mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis
Developmental Cell. Vol 15(6) 12/09/08:813-828 (Login to HAM TMC Library for PDF)
Eric Chang
Feb. 3 Bonita Chan Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
Cell. Vol 135(5) 11/28/08:865-878 (Login to HAM TMC Library for PDF)
Adrian Lee
Feb. 17 Alexandra Richter
Abstract, Presentation
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock Steffi Oesterreich
March 3 Yen-Chao Wang
Paper, Supplemental Info,
RPN2 gene confers docetaxel resistance in breast cancer Rachel Schiff/
CK Osborne
March 17


The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells
Cancer Research.69 2009: 1722-1727 (Login to HAM TMC Library for PDF)
Suzanne Fuqua
April 7 Ryan Hartmaier
Paper, Supplemental Info
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing Steffi Oesterreich
April 21 No Journal Club due to AACR
May 5 No Journal Club
May 19 Jay Reddy

Distinct Thresholds Govern the Biological Output of Myc
Cancer Cell. 14(6) 12/09/08: 447-457 (Login to HAM TMC Library for PDF)

Yi Li
June 2 No Journal Club Summer Break
June 16 No Journal Club Summer Break
July 7 No Journal Club Summer Break
July 21 No Journal Club Summer Break
Aug. 4 No Journal Club Summer Break
Aug. 18 Bhuvanesh Dave
Paper, Presentation
Regulation of mammary stem/progenitor cells by PTEN/Akt/b-Catenin signaling Jenny Chang
Sept. 1 Angelo Casa
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer
Cancer Cell. Vol 16(1) 07/07/09: 21-32 (Login to HAM TMC for pdf)
Adrian Lee
Sept. 15 Yuanxin Xi
Paper, Presentation
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing Wei Li (DLDCC)
Oct. 6 Jason Garee
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
Cell. Vol 138(6) 09/18/09: 1082-1095 (Login to HAM TMC for pdf)
Steffi Oesterreich
Oct. 20 Svasti Haricharan
Paper and Supplement Info
A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression
Yi Li
Nov. 3 No Journal Club
Nov. 17 Evelin Young
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells Eric Chang
Dec. 1 Albert Chen
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
Dec. 15 No Journal Club due to SABCS

Please remember to submit your Journal Club paper two weeks prior to your scheduled presentation. E-mail you paper to Robin Sample.

After you give your talk, please e-mail your PowerPoint file to Robin Sample to be uploaded to this page.

2008 Journal Club Schedule

2010 Journal Club Schedule

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