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Lester and Sue Smith Breast Center

Houston, Texas

The Lester and Sue Smith Breast Center's mission is to improve prevention, diagnosis and treatment of breast disease.
Lester & Sue Smith Breast Center
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Eric C. Chang, Ph.D.

Associate Professor, Department of Molecular and Cellular Biology

D. Craig Allred, M.D.Phone: 713-798-3519
Fax: 713-798-1642



1977-1981 - BS, National Taiwan University, Plant pathology, Taipei, Taiwan.
1984-1989 - Ph. D: State University of New York at Buffalo, Biochemistry Buffalo, New York.
1989-1992 - Post doctoral fellow, Cold Spring Harbor lab., Molecular Biology and Genetics, Cold Spring Harbor, NY.

Research Interests:

Ras proteins are key switches for signal transduction pathways that are central for the control of cell growth and differentiation. We are using a combination of Genetic, Molecular and Cell Biology, and Biochemistry to address two key issues:

  1. Ras proteins engage in a complex network of molecular interactions. How is any given Ras protein connected to this web of interactions with specificity?
  2. Which downstream pathways controlled by Ras are important for cancer formation?

Honors and Awards:

1989 - National Research Service Award (NIH)
1992 - Andrew Seligson Memorial Award (Cold Spring Harbor Lab)


1997 - Whitehead Fellowship (NYU)
1999 - Goddard Fellowship (NYU)

Professional Associations and Affiliations:

American Society of Cell Biology
American Society of Microbiology
American Association for the Advancement of Science
American Society for Biochemistry and Molecular Biology

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