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Lester and Sue Smith Breast Center

Houston, Texas

The Lester and Sue Smith Breast Center's mission is to improve prevention, diagnosis and treatment of breast disease.
Lester & Sue Smith Breast Center
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Gary Chamness, Ph.D. - Publications

Publications, Abstracts

Selected publications:

S. G. Hilsenbeck, P. M. Ravdin, C. de Moor, G. C. Chamness, C. K. Osborne, and G. M. Clark (1998). Time-dependence of hazard ratios for prognostic factors in primary breast cancer. Breast Cancer Res. Treat., 52:227-237.

R. C. Zellars, S. G. Hilsenbeck, G. M. Clark, D. C. Allred., T. S. Herman, G. C. Chamness, R. M. Elledge (2000). Prognostic value of p53 for local failure in mastectomy-treated breast cancer patients. J Clin Oncol 18:1906-1913. [PDF]

R. Schiff, P. Reddy, M. Ahotupa, E. Coronado-Heinsohn, M. Grim, S. G. Hilsenbeck, R. Lawrence, S. Deneke, R. Herrera, G. C. Chamness, S. A. Fuqua, P. H. Brown, C. K. Osborne (2000). Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst 92(23):1926-1934. [PDF]

J. Chang, G.M. Clark, D.C. Allred, S. Mohsin, G. Chamness, R.M. Elledge (2003). Survival of patients with metastatic breast carcinoma. Cancer 97(3):545-553. [PDF]

C.K. Osborne, V. Bardou, T.A. Hopp, G.C. Chamness, S.G. Hilsenbeck, S.A. Fuqua, J. Wong, D.C. Allred, G.M. Clark, R. Schiff (2003). Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J Natl Cancer Inst 95(5):353-361. [PDF]

J.C. Chang, E.C. Wooten, A. Tsimelzon, S.G. Hilsenbeck, M.C. Guiterrez, R. Elledge, S. Mohsin, C.K. Osborne, G.C. Chamness, D.C. Allred, P. O'Connell (2003). Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet 362 (9381):362-369, 2003. [Abstract]

R. Schiff, G.C. Chamness, P.H. Brown (2003). Advances in breast cancer treatment and prevention: Preclinical studies on aromatase inhibitors and new SERMs. Breast Cancer Res 5:228-231. [PDF]

L.A. deGraffenried, T.A. Hopp, A.J. Valente, R.A. Clark, G.C. Chamness, S.A. Fuqua (2004). Regulation of the estrogen receptor α minimal promoter by SP1, USF, and ERα. Breast Cancer Res Treat 85:111-120.

X. Zhang, K. Podsypanina, S. Huang, S.K. Mohsin, G.C. Chamness, S. Hatsell, P. Cowin, R. Schiff, Y. Li (2005). Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collab­orating oncogenic mutations . Oncogene (2005) 24:4220-31. [PDF]

S.K. Mohsin, H.L. Weiss, M.C. Gutierrez, G.C. Chamness, R. Schiff, M.P. Digiovanna, C.X. Wang, S.G. Hilsenbeck, C.K. Osborne, D.C. Allred, R. Elledge, J.C. Chang (2005). Neoadjuvant trastuzumab induces apoptosis in primary breast cancers. J Clin Oncol 23:2460-2468. [PDF]

J.C. Chang, E.C. Wooten, A Tsimelzon, S.G. Hilsenbeck, M.C. Gutierrez, Y.L. Tham, M. Kalidas, R. Elledge, S. Mohsin, C.K. Osborne, G.C. Chamness, D.C. Allred, M.T. Lewis, H. Wong, P. O’Connell (2005). J Clin Oncol 23:1169-1177. [PDF]

Chang JC, Makris A, Gutierrez MC, Hilsenbeck SG, Hackett JR, Jeong J, Liu ML, Baker J, Clark-Langone K, Baehner FL, Sexton K, Mohsin S. Gray T, Alvarez L, Chamness GC, Osborne CK, Shak S. Gene expression patterns in formalin-fixed, paraffin-embedded core biopsies predict docetaxel chemosensitivity in breast cancer patients. Breast Cancer Res Treat 108(2):233-240, 2008. [PDF]

Creighton CJ, Osborne CK, van de Vijver MJ, Foekens JA, Klijn JG, Horlings HM, Nuyten D, Wang Y, Zhang Y, Chamness GC, Hilsenbeck SG. Lee AV, Schiff R. Molecular profiles of progesterone receptor loss in human breast tumors. Breast Cancer Res Treat 2008 Apr 19. [Epub ahead of print] [PDF]

Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008 May 7;100(9):672-9. Epub 2008 Apr 29. [PDF]

Publications, Abstracts

Selected Abstracts:

G.C. Chamness. Perspectives on the biology of breast cancer. Gordon Research Conference on Mammary Gland Biology, June 1999.

G.C. Chamness, P.F. Smith, S. Amir, L.D. Loriaux. Mock study section. 81st Annual Endocrine Society Meeting, San Diego, June 1999. Abstract L-12, p18, 1999.

G.C. Chamness. Writing for your grant reviewers. 82d Annual Endocrine Society Meeting, Toronto, June, 2000.

J.M. Harvey, D.C. Allred, G.C. Chamness, C.K. Osborne, G.M. Clark. Validation of the prognostic significance of mitosin in node-negative patients [abstract 127]. 23d Annual San Antonio Breast Cancer Symposium, Dec. 2000. Breast Cancer Res Treat 64:42, 2000.

C.K. Osborne, V.-J. Bardou, S.G. Hilsenbeck, S.A.W. Fuqua, T. Hopp, G. Chamness, J. Wong, R. Schiff, C. Allred, G. Clark. The estrogen receptor coactivator AIB1 (SRC3) in combination with HER-2 is a prognostic and predictive marker in patients with breast cancer [abstract 129]. Proc Am Soc Clin Oncol 21:33a, 2002.

J.C. Chang, S. Mohsin, H. Weiss, S.G. Hilsenbeck, C. Gutierrez, A. Lucci, M. Kalidas, G.C. Chamness, K. Osborne, R. Elledge. Induction of apoptosis without change in cell proliferation in primary breast cancers with neoadjuvant trastuzumab. 26 th Annual San Antonio Breast Cancer Symposium, Dec. 2003. Breast Cancer Res Treat 82(Suppl 1):S13, 2003.
Publications, Abstracts

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