About the Core

The Integrated Microscopy Core is a light and electron microscopy facility supporting investigators at Baylor College of Medicine and the Texas Medical Center.

We gratefully acknowledge the support of the Advanced Technology Cores at Baylor College of Medicine, the Dan L. Duncan Cancer Center and the Texas Medical Center Digestive Diseases Center. 

Acknowledgment of the IMC Peer-Review Publications:

“This project was supported by the Integrated Microscopy Core at Baylor College of Medicine with funding from the NIH (DK56338, and CA125123), the Dan L. Duncan Cancer Center, and the John S. Dunn Gulf Coast Consortium for Chemical Genomics.”

Equipment and Services

Instruments Available in the IMC:

  • GE Healthcare OMX 3D Structured Illumination Microscope and TIRF
  • Nikon A1-Rs Inverted Laser Scanning Microscope with spectral Detection System
  • GE Healthcare Inverted Deconvolution/ Image Restoration Microscope
  • Biotek Cytation 5 Imager and Plate Reader (Fluorescence, Absorbance, Luminescence)
  • Nikon TE-2000 Epi-Fluorescence Microscope
  • Nikon Ci-L Upright Microscope
  • Titretek Plating System
  • Beckman Biomek Span 8 NX Robot
  • VALA IC-200 High Throughput Microscope
  • Hitachi H7500 Transmission Electron Microscope
  • JEOL 1230 Transmission Electron Microscope
  • Leica U6  and U7 Ultramicrotomes

Which Instrument is Best for Your Project?

Sample type/Instument

Services Available in the IMC:

  • FREE consultation in experimental design and data interpretation (by appointment only)
  • Tech assist in experiment setup, execution and  imaging (limited)
  • Assisted Use on all instruments
  • Laminar flow hood and CO2 incubator for limited time cell maintenance and live experiments (no live virus or bacteria accepted into the facility)
  • High Throughput Microscopy experiments
  • Image Analysis
  • TEM sample prep and processing (tech assist and training)
  • TEM sample thick and thin sectioning (tech assist and training)