Positions

Associate Professor
Neurosurgery
Director of Cerebrovascular Surgery
Baylor College of Medicine
Houston, TX, US
Chief of Neuroendovascular Service, Baylor St. Luke's Medical Center

Education

MD from University of Toronto
Residency at University of Utah
Neurosurgery
Clinical Fellowship at University of Toronto
Skull base and cerebrovascular surgery
Clinical Fellowship at University at Buffalo
Endovascular neurosurgery
MPH from University of Utah

Certifications

Certified - American Board of Neurological Surgeons
American Board of Neurological Surgeons
Certified - Royal College of Physicians and Surgeons of Canada
Royal College of Physicians and Surgeons of Canada
Texas Medical License
Texas Medical Board

Professional Statement

My goal is to strive for excellence in patient care, cerebrovascular research, and medical education

Selected Publications

  • "3-D vascular skeleton extraction and decomposition."
  • "3D Vascular decomposition and classification for computer-aided detection."
  • "A proposed grading system for endovascular treatment of cerebral arteriovenous malformations: Buffalo score."
  • "Acute stroke therapy: are we ready for primetime clinical trials?."
  • "Adjunctive use of eptifibatide for complication management during elective neuroendovascular procedures."
  • "Cervical carotid artery stenosis: latest update on diagnosis and management."
  • "Complications after treatment with pipeline embolization for giant distal intracranial aneurysms with or without coil embolization."
  • "Computed tomography (CT) perfusion in the treatment of acute stroke."
  • "Double-barrel stent-assisted coiling of a basilar artery fenestration aneurysm."
  • "Early postmarket results after treatment of intracranial aneurysms with the pipeline embolization device: a U.S. multicenter experience."
  • "Endovascular coil embolization of a very small ruptured aneurysm using a novel microangiographic technique: technical note."
  • "Endovascular therapy of wake-up strokes in the modern era of stent retriever thrombectomy."
  • "External carotid dissection and external carotid proatlantal intersegmental artery with subclavian steal prompting external carotid and subclavian artery stenting."
  • "Feasibility, safety, and periprocedural complications associated with endovascular treatment of selected ruptured aneurysms under conscious sedation and local anesthesia."
  • "First reported use of retrievable stent technology for removal of a large septic embolus in the middle cerebral artery."
  • "Horizontal deployment of an intracranial stent via an antegrade approach for coil embolization of a basilar apex aneurysm: technical note."
  • "Intra-arterial thrombolysis and thrombectomy for acute ischemic stroke: technique and results."
  • "Intracerebral hemorrhage secondary to intravenous and endovascular intraarterial revascularization therapies in acute ischemic stroke: an update on risk factors, predictors, and management."
  • "Intravascular ultrasound in the evaluation and management of cerebral venous disease."
  • "Intravascular ultrasound-guided thrombus retrieval with a multipurpose-angled catheter during carotid artery stenting."
  • "Intravenous thrombolysis and endovascular therapy for acute ischemic stroke with internal carotid artery occlusion: a systematic review of clinical outcomes."
  • "Letter to the editor: Multimodal treatment of co-existent callosal cavernous malformation and anterior communicating artery aneurysm associated with an infraoptic anterior cerebral artery."
  • "Long-term results of enterprise stent-assisted coiling of cerebral aneurysms."
  • "Panacea or problem: flow diverters in the treatment of symptomatic large or giant fusiform vertebrobasilar aneurysms."
  • "Posterior inferior cerebellar artery to posterior inferior cerebellar artery in situ bypass for the treatment of Bow hunter's-type dynamic ischemia in holovertebral dissection."
  • "Results of endovascular treatment of middle cerebral artery aneurysms after first giving consideration to clipping."
  • "Results of stent-assisted vs non-stent-assisted endovascular therapies in 489 cerebral aneurysms: single-center experience."
  • "Revisiting angioplasty without stenting for symptomatic intracranial atherosclerotic stenosis after the stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) study."
  • "Solitaire Flow Restoration thrombectomy for acute ischemic stroke: retrospective multicenter analysis of early postmarket experience after FDA approval."
  • "Stenting of the vertebral artery origin with ostium dilation: technical note."
  • "Stroke intervention for middle cerebral artery thrombus in a young patient with an ipsilateral Spetzler-Martin grade V arteriovenous malformation."
  • "Tandem symptomatic internal carotid artery and persistent hypoglossal artery stenosis treated by endovascular stenting and flow reversal."
  • "Treatment and outcomes of acute intracranial vertebrobasilar artery occlusion: one institution's experience."
  • "Unyielding progress: carotid stenting cases from Millard Fillmore Gates Circle Hospital in Buffalo, New York."
  • "Utility of CT perfusion scanning in patient selection for acute stroke intervention: experience at University at Buffalo Neurosurgery-Millard Fillmore Gates Circle Hospital."
  • "Utility of intravascular ultrasound in intracranial and extracranial neurointerventions: experience at University at Buffalo Neurosurgery-Millard Fillmore Gates Circle Hospital."
  • "Vascular decomposition using weighted approximate convex decomposition."
  • "Surpass Flow Diverter for Treatment of Posterior Circulation Aneurysms." AJNR. 2016 December 22
  • "Use of self-expanding stents for better intracranial flow diverter wall apposition." Interv Neuroradiol. 2016 December 12
  • "Vessel perforation during stent retriever thrombectomy for acute ischemic stroke: technical details and clinical outcomes." JNIS. 2016 September 29
  • "Aneurysms with persistent patency after treatment with the Pipeline Embolization Device." JNS. 2016 September 16
  • "An intraoperative look at failure of flow diversion: when additional or alternative treatments should be considered." World Neurosurg. 2016 July 12
  • "Pediatric Cerebral Cavernous Malformations: Genetics, Pathogenesis, and Management." Surgical Neurology International. 2016 December 28
  • "Application of 4D-DSA for Dural Arteriovenous Fistulas." World Neurosurg. 2016 May 14
  • "Evaluation of C-arm CT metal artifact reduction algorithm during intra-aneurysmal coil embolization." European Journal of Radiology. 2016 July
  • "Pediatric knowledge update: approach to the management of Vein of Galen aneurysmal malformations in neonates." Surgical Neurology International. 2016 May 13
  • "Clinical and Procedural Predictors of Outcomes From the Endovascular Treatment of Posterior Circulation Strokes." Stroke. 2016 March
  • "ARTS (Aspiration-Retriever Technique for Stroke): Initial clinical experience." Interventional Neuroradiology. 2016 January 21
  • "Safety, efficacy, and short-term follow-up of the use of Pipeline Embolization Device in small (<2.5 mm) cerebral vessels for aneurysm treatment: single institution experience." Neuroradiology. 2015 December 23
  • "Treatment of Distal Anterior Circulation Aneurysms With the Pipeline Embolization Device: A US Multicenter Experience." Neurosurgery. 2015 November 16
  • "Two-color 3D-3D fusion of selective rotational cerebral angiograms: a novel approach to imaging in cerebrovascular neurosurgery." JNIS. 2015 November 16
  • "Endovascular reconstruction of unruptured intradural vertebral artery dissecting aneurysms with the Pipeline embolization device." JNIS. 2015 November 6
  • "Treatment failure of fetal posterior communicating artery aneurysms with the pipeline embolization device." JNIS. 2015 September 11
  • "Techniques in distal access of wide-necked giant intracranial aneurysms during treatment with flow diversion." Surgical Neurology International. 2015 May 28
  • "Successful treatment of a giant pediatric fusiform basilar trunk aneurysm with surpass flow diverter." JNIS. 2015 June 10
  • "Onyx embolization in distal dissecting posterior inferior cerebellar artery aneurysms." JNIS. 2015 April 2
  • 1. Ghali MGZ, Srinivasan VM, Cherian J, Kim L, Siddiqui A, Aziz-Sultan MA, Froehler M, Wakhloo A, Savageau E, Rai A, Chen SR, Johnson J, Lam SK, Kan P. "Pediatric intracranial aneurysms: considerations and recommendations for follow-up imaging." World Neurosurg. 2017 October 3
  • 2. Stowe RC, Kan P, Breen DB, Agarwal S. "Mechanical thrombectomy for pediatric acute stroke and ventricular assist device." Brain Dev. 2017 August 24
  • Cherian J, Srinivasan VM, Kan P, Duckworth EAM. "Double-Barrel STA-MCA Bypass: Can It Be Considered “High-Flow?”." Operative Neurosurgery. 2017 August 18
  • Srinivasan VM, Chintalapani G, Duckworth EAM, Kan P. "Advanced cone-beam CT venous angiographic imaging." J Neurosurg. 2017 August 18
  • Wilson TA, Leslie-Mazwi T, Hirsch JA, Frey C, Kim TE, Spiotta AM, Leacy R, Mocco J, Albuquerque FC, Ducruet AF, Cheema A, Arthur A, Srinivasan VM, Kan P, Mokin M, Dumont T, Rai A, Singh J, Wolfe SQ, Fargen KM. "A multicenter study evaluating the frequency and time requirement of mechanical thrombectomy." J Neurointerv Surg. 2017
  • Srinivasan VM, Carlson AP, Mokin M, Cherian J, Chen SR, Puri A, Kan P. "Prolapse of the Pipeline embolization device in aneurysms: incidence, management, and outcomes." Neurosurg Focus. 2017 June
  • De Macedo Rodrigues K, Kühn AL, Tamura T, Dabus G, Kan P, Marosfoi MG, Lozano JD, Perras M, Brooks C, Howk MC, Hou SY, Rex DE, Massari F, Gounis MJ, Wakhloo AK, Puri AS. "Pipeline Embolization Device for Pericallosal Artery Aneurysms: A Retrospective Single Center Safety and Efficacy Study." Oper Neurosurg. 2017 May 17
  • Srinivasan VM, Chen SR, Camstra KM, Chintalapani G, Kan P. "Development of a recalcitrant, large clot burden, bifurcation occlusion model for mechanical thrombectomy." Neurosurg Focus. 2017 April
  • Mokin M, Primiani CT, Ren Z, Kan P, Duckworth E, Turner RD 4th, Turk AS, Fargen KM, Dabus G, Linfante I, Dumont TM, Brasiliense LB, Shallwani H, Snyder KV, Siddiqui AH, Levy EI. "Endovascular Treatment of Middle Cerebral Artery M2 Occlusion Strokes: Clinical and Procedural Predictors of Outcomes." Neurosurgery. 2017 May 10
  • 11. Srinivasan VM, Mokin M, Duckworth EA, Chen S, Puri A, Kan P. "Tourniquet parent artery occlusion after flow diversion." J Neurointerv Surg. 2017 March 6
  • "Flow diversion for the treatment of posterior inferior cerebellar artery aneurysms: a novel classification and strategies."
  • "Flow diversion for anterior choroidal artery (AChA) aneurysms: a multi-institutional experience."
  • "Spinal Dural Arteriovenous Fistula and Concomitant Intramedullary Spinal Lesion."
  • "Multimodal Treatment of Intracranial Aneurysms in Children: Clinical Case Series and Review of the Literature."
  • "John Allcock and a brief history of Allcock’s test."
  • Srinivasan VM, Chintalapani G, Camstra KM, Effendi ST, Cherian J, Johnson JN, Chen SR, Kan P. "Fast acquisition cone-beam computed tomography: initial experience with a 10 s protocol." JNIS. 2018 January
  • 1. Williams MM, Wilson TA, Leslie-Mazwi T, Hirsch JA, Kellogg RT, Spiotta AM, De Leacy R, Mocco J, Albuquerque F, Ducruet AF, Arthur A, Srinivasan VM, Kan P, Mokin M, Dumont TM, Reeves A, Singh J, Wolfe SQ, Fargen KM. "The burden of neurothrombectomy call: a multicenter prospective study." J Neurointerv Surg. 2018 April 20
  • Mokin M, Chinea A, Primiani CT, Ren Z, Kan P, Srinivasan VM, Hanel R, Aguilar-Salinas P, Turk AS, Turner RD, Chaudry MI, Ringer AJ, Welch BG, Mendes Pereira V, Renieri L, Piano M, Elijovich L, Arthur AS, Cheema A, Lopes DK, Saied A, Baxter BW, Hawk H. "Treatment of blood blister aneurysms of the internal carotid artery with flow diversion." J Neurointerv Surg. 2018 February 24
  • Zaki Ghali MG, Srinivasan VM, Wagner K, Rao C, Chen SR, Johnson JN, Kan P.. "Cognitive sequelae of subarachnoid hemorrhage, cerebral aneurysm treatment, and neuropsychological assessment.." World Neurosurg.. 2018 June 29 Pubmed PMID: 29966787
  • Srinivasan VM, Kaufmann A, Kan P, Duckworth EA.. "Surgical Reconstruction to Allow Endovascular Access for Flow Diversion of Giant Cavernous Aneurysm: A Combined Approach.." Cureus.. 2018 March 28 Pubmed PMID: 29850376

Memberships

American Association of Neurological Surgeons
Congress of Neurological Surgeons
Society of Neurointerventional Surgery

Funding

Pipeline Embolization Device for Intracranial aneurysms in PEDiatric patients (PEDIPED): a multi-center trial
Grant funding from Medtronic
Characterization of Arterial Occlusive Thrombi in Acute Ischemic Stroke (CLOTS)
Grant funding from Stryker Neurovascular
A Recalcitrant Swine Model of Large Vessel Occlusion
Grant funding from MicroVention Terumo
Systematic Evaluation of Patients Treated with Neurothrombectomy Devices for Acute Ischemic Stroke (STRATIS) Registry
Grant funding from Medtronic
Safety and Effectiveness of the Treatment of Wide Neck, Saccular Intracranial Aneurysms with the Neuroform Atlas Stent System
Grant funding from Stryker Neurovascular
The WEB Intrasaccular Therapy Study (WEB-IT)
Sequent Medical
Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms
Grant funding from MicroVention Terumo
The Surpass Intracranial Aneurysm Embolization System Pivotal Trial to Treat Large or Giant Wide Neck Aneurysms
Grant funding from Stryker Neurovascular
Prospective Study on Embolization of Intracranial Aneurysms with Pipeline Embolization Device
Grant funding from Medtronic
Apollo Onyx Delivery Micro Catheter Post Market Safety Study
Grant funding from Medtronic
Preliminary Study of Super-selective Intra-arterial Infusion of Human Mesenchymal Stem Cell-based Therapy in a Rabbit Glioblastoma Model
- #2P50CA127001
Grant funding from National Cancer Institute
MD Anderson Cancer SPORE

Skills

Brain aneurysms
Subarachnoid hemorrhage
Brain arteriovenous malformations and fistula
Cavernous malformations
Carotid stenosis
Intracranial stenosis
Acute ischemic stroke