Assistant Professor
Mol. & Human Gen./B Lee Lab
Baylor College of Medicine
Assistant Director - Clinical Lab
Human Genome Sequencing Center
Baylor College of Medicine


BS from Rice University
MD from Baylor College of Medicine
Postdoctoral Fellowship at Baylor College of Medicine
Human Genome Sequencing Center
Residency at Louisiana State University Health Sciences Center
Internal Medicine
Clinical Fellowship at the National Institutes of Health
Clinical Genetics, NIH-Johns Hopkins Consortium
Fellowship at the National Institutes of Health
Molecular Genetics


Internal Medicine
American Board of Internal Medicine
Clinical Genetics
American Board of Medical Genetics and Genomics
Molecular Genetics
American Board of Medical Genetics and Genomics

Professional Interests

  • Connective Tissue Disorders (Marfan, Loeys-Dietz, Ehlers-Danlos)
  • Adult and Cardiovascular Genetics
  • Xia-Gibbs syndrome
  • Precision Medicine
  • Bioinformatics

Professional Statement

My clinical and research interests involve connective tissue disorders such as Marfan syndrome and Loeys-Dietz syndrome, conditions that lead to aortic aneurysms and dissections. I am particularly interested in identifying new genes associated with such aortopathies and exploring the mechanisms of genetically-mediated aneurysm development. I also study Xia-Gibbs syndrome, a developmental disorder due to truncating mutations in the AHDC1 gene. The goal of these research efforts is to develop new therapies to improve outcomes. Among the tools I use are whole exome and genome sequencing as well as RNAseq.

As a member of the adult genetics team I diagnose and manage adults with a variety of genetic conditions (e.g., cancer). I am also the assistant director of the HGSC CAP/CLIA clinical lab where I perform analysis, interpretation, and reporting of sequencing data. I am committed to the growing field of personalized medicine through the eMERGE and BCM Cardiovascular Disease Genetics efforts. Lastly, I am dedicated to education and enjoy teaching about principles of genetics.

Selected Publications