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Positions
- Professor Emeritus
- Medicine-Cardiovascular Sciences
- Baylor College of Medicine
- Houston, TX, US
- Adjunct Professor
- Bioengineering
- Rice University
- Houston, TX
- Adjunct (Associate) Professor
- Electrical and Mechanical Engineering
- University of Houston
- Houston, TX
Education
- B.S. from University Of Washington
- Electrical Engineering
- Ph.D. from University Of Washington
- Post-doctoral Fellowship from Rice University
Honors & Awards
- NDEA Title IV Fellow
- NIH Research Career Development Award
- NIH MERIT Award
- AAMI Foundation Laufman Prize for Career Achievement
- Made the first 2-D (C-Scan) ultrasonic images of human atherosclerotic plaques showing that calcium was responsible for the high attenuation and would likely cause shadowing in ultrasonic images (1969)
- Designed a high-resolution (100 nm) tissue Doppler displacement system and measured carotid artery wall motion in mice (2004)
- Developed instrumentation and transducers for noninvasive measurement of central (1992) and regional (1996) flow velocity, and aortic pulse-wave velocity (1997) in mice
- Developed the first ultrasonic displacement (tissue Doppler) system to measure ventricular wall thickening (myocardial strain) in animals (1981) and in man (1987).
- Developed the first modular multipurpose ultrasonic system to measure regional blood flows and cardiac dimensions in large animals (1975) and in rats (1976)
- Developed the first 20 MHz pulsed Doppler velocimeter (1973) and catheter to measure coronary blood flow velocity (1974) and made the first measurements of coronary flow Reserve in man (1977)
Professional Statement
Since 1970 Dr. Hartley has been involved in the design, development, and application of ultrasonic instrumentation for cardiovascular measurements in man and in animal models of human diseases. His group designed the first high frequency (20 MHz) pulsed Doppler velocimeter and catheters to measure coronary blood flow velocity and reserve in man (1973), the first multichannel pulsed Doppler system and implantable probes to measure regional blood flow in chronically instrumented animals (1976), and the first tissue Doppler to measure ventricular wall thickening (myocardial strain) in animals (1981) and in man (1987). Since 1992, he has been developing and using similar methods noninvasively to measure blood flow velocity and arterial wall motion in mice with unprecedented precision (100 nm) and temporal resolution (100 us). His group recently showed that left main coronary flow reserve, measured noninvasively in mice, is reduced by many types of heart disease and loading and is a sensitive index of global cardiac function. The ultrasonic technology developed by Dr. Hartley's laboratory has been incorporated into many clinical and research systems.
Memberships
- American Institute for Medical and Biological Engineering
- IEEE and EMBS
- Biomedical Engineering Society
- Cardiovascular System Dynamics Society
- American Institute for Ultrasound in Medicine
- American Heart Association
- American Physiological Society
- Institute of Electrical and Electronic Engineers