Email

pzhang@bcm.edu

Positions

Professor

Molec. Physiology/Zhang
Baylor College of Medicine
Houston, TX US

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Education

Advanced Training from Baylor College Of Medicine

01/1998 - Houston, TX United States

Ph.D. from University Of Wisconsin, Madison

01/1993 - Madison, WI United States

M.S. from Shanghai Medical University

01/1987 - Shanghai, China, People's Rep

B.S. from Shanghai Medical University

01/1984 - Shanghai, China, People's Rep

Professional Interests

• Cell and Developmental Biology
• Human Disease
• Molecular Biology and Genetics

Professional Statement

Research in this laboratory focus on the control of cell division cycles in development and disease. We are particularly interested in how the cell cycle checkpoints are activated in response to internal and external stimuli and how these checkpoints prevent cell cycle progression.

Websites

Selected Publications

• Li M, Shin YH, Hou L, Huang X, Wei Z, Klann E, Zhang P "The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory.." Nat. Cell Biol.. 2008 Sep;10(9):1083-9. Pubmed PMID: 19160489
• Li M, York JP, Zhang P "Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.." Mol. Cell. Biol.. 2007 May;27(9):3481-8. Pubmed PMID: 17325031
• Wei Z, Peddibhotla S, Lin H, Fang X, Li M, Rosen JM, Zhang P "Early-onset aging and defective DNA damage response in cdc14b-deficient mice.." Mol. Cell. Biol.. 2011 Apr;31(7):1470-7. Pubmed PMID: 21262768
• Huang X, Hatcher R, York JP, Zhang P "Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.." Mol. Biol. Cell. 2005 Oct;16(10):4725-32. Pubmed PMID: 16030258