Email

kevinp@bcm.edu

Positions

Assistant Professor

Molecular and Cellular Biology

Academic Co-Director

Protein and Monoclonal Antibody Production Core

Baylor College of Medicine Houston, TX

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Education

Postdoctoral Fellowship at UCSF

San Francisco, CA

Structural and Molecular Biology

PhD from Harvard University

Cambridge, MA

Chemistry and Chemical Biology

BSc from California State University, Long Beach

Long Beach, CA

Biochemistry

Professional Interests

• Energy Balance
• Lipid Homeostasis
• Experimental Therapeutics

Professional Statement

The thyroid hormone system is a key regulator of fundamental metabolic processes, including the control of basal metabolic rate. A major current focus of my group is understanding how thyroid hormone receptor (TR) signaling regulates adaptive thermogenesis, the conversion of excess energy (e.g. fat) to heat, with an eye towards manipulating this system pharmacologically to develop new therapeutics to treat diabetes and obesity. We use a multidisciplinary approach to that combines pharmacology, genetic mouse models, biochemistry, and structural studies to develop a holistic understanding of TR mediated beige and brown fat thermogenesis.

Websites

Selected Publications

• "Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat." Cell Reports. 2015 :
• "Hunt for new obesity pills." :