Jian Zhou
Picture
Jian Zhou
Postdoctoral Associate
Positions
- Postdoctoral Associate
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Department of Molecular and Human Genetics
Laboratory of Dr. Huda Zoghbi
Baylor College of Medicine
Houston, TX US
Education
- BA from Wuhan University
- Wuhan, China
- PhD from Texas A&M University
- College Station, Texas United States
Professional Interests
- Molecular basis of autism and neurodevelopmental disorders
- Pathogenesis of Rett syndrome
Selected Publications
- Jian Zhou, Hamdan Hamdan, Hari Krishna Yalamanchili, Kaifang Pang, Amy E. Pohodich, Joanna Lopez, et al "Disruption of MeCP2–TCF20 complex underlies distinct neurodevelopmental disorders." Proc Natl Acad Sci U S A .. 2022 Jan 25;4 Pubmed PMID: 35074918
- GBS Rivas*, J Zhou*, C Merlin, PE Hardin "CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN." Curr Biol. 2021 Jul 30; Pubmed PMID: 34331859
- Aya Ito-Ishida, Steven A Baker, Roy V Sillitoe, Yaling Sun, Jian Zhou, Yukiteru Ono, Junichi Iwakiri, Michisuke Yuzaki, Huda Y Zoghbi "MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons." J Neurosci.. 2020 Nov 4;40(45):8746-8766. Pubmed PMID: 33046553
- Kaifang Pang, Li Wang, Wei Wang, Jian Zhou, Chao Cheng, Kihoon Han, Huda Y Zoghbi, Zhandong Liu "Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders." Genome Res.. 2020 Jun 1;30(6):835-848. Pubmed PMID: 32554779
- Parul Agrawal, Jerry H Houl, Kushan L Gunawardhana, Tianxin Liu, Jian Zhou, Mark J Zoran, Paul E Hardin "Drosophila CRY entrains clocks in body tissues to light and maintains passive membrane properties in a non-clock body tissue independent of light." Curr Biol.. 2017 Aug 21;27(16):2431-2441. e3. Pubmed PMID: 28781048
- Jian Zhou, Wangjie Yu, Paul E Hardin "CLOCKWORK ORANGE enhances PERIOD mediated rhythms in transcriptional repression by antagonizing E-box binding by CLOCK-CYCLE." PLoS Genet.. 2016 Nov 4;12(11):e1006430. Pubmed PMID: 27814361
- Jian Zhou, Wangjie Yu, Paul E Hardin "ChIPping away at the Drosophila clock." Methods Enzymol.. 2015 Jan 1;551:323-347. Pubmed PMID: 25662463
- Huan Nan Wang, Yan Xu, Ling Jie Tao, Jian Zhou, Meng Xi Qiu, Yu Hang Teng, Feng Jiao Deng "Identification and characterization of the pumilio-2 expressed in zebrafish embryos and adult tissues." Mol Biol Rep.. 2012 Mar;39(3):2811-2819. Pubmed PMID: 21660475
- Yan Xu, Huannan Wang, Jian Zhou, Yong Lei, Yaping Zhou, Qiwen Yang, Ding Ye, Wenhua Li, Fengjiao Deng "Zebrafish Nanos interacts with and regulates the phosphorylation of Mylz2." Biochimie.. 2010 Dec 1;92(12):1812-1817. Pubmed PMID: 20673786
- Sameer S Bajikar, Ashley G Anderson, Jian Zhou, Mark A Durham, Alexander J Trostle, Ying-Wooi Wan, Zhandong Liu, Huda Y Zoghbi "MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function." eLife. 2023 Feb 27; Pubmed PMID: 36848184
Funding
- Pathway to Independence Awards (K99/R00) Grant funding from National Institutes of Health/National Institute of Neurological Disorders and Stroke
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