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BCM tackles Alzheimer's on all fronts: Interdepartmental Research

The fight to find a more effective treatment for Alzheimer's disease goes beyond the Alzheimer's Disease and Memory Disorders Center. Researchers in other BCM departments are focusing their work on this debilitating disease.

Dr. Hui Zheng, professor in the Huffington Center on Agingand the Department of Molecular and Human Genetics at BCM, and her colleagues are now using what is called knock-in mouse models to zero in on the genes and molecules that play a role in the disease. See New generation of mouse models mimic progression of AD.

Dr. Robia Pautler, assistant professor of molecular physiology and biophysics at BCM, and her team are researching MRI (magnetic resonance imaging) and imaging techniques to use as diagnostic tools to increase early detection so treatment can begin before cognitive decline. See Identification of axonal transport deficits may aid in early detection, treatment.

Dr. Jeffrey Noebels, professor of neurology, neuroscience, and molecular and human genetics, and his research team in the Blue Bird Developmental Neurogenetics Laboratory at BCM are exploring new pharmacology to rescue patterns of abnormal brain network activity in mouse models of Alzheimer's disease. His work also involves collaborations with ADMDC researchers.