Molecular and Human Genetics News
Unexplained developmental disorder linked to gene involved in essential cellular processes Aug 18, 2016 Researchers have linked a neurodevelopmental disorder for which there was no known cause to a gene involved in essential mechanisms a cell uses to translate DNA into protein.
Rett and MECP2 duplication syndrome mice have identical malfunction in neural circuits that can be corrected by DBS Aug 4, 2016 Deep brain stimulation reversed circuit malfunctions in mouse models of both Rett syndrome and MECP2 duplication syndrome.
Leaky calcium triggers brainstem blackout that results in sudden cardiac death Aug 1, 2016 Researchers report how a mutation in a gene involved in the regulation of calcium inside brain cells can help trigger blackouts of the brainstem, increasing the risk of sudden unexpected death.
Center for Genome Architecture explores 3-D structure of DNA Aug 1, 2016 Dr. Erez Lieberman Aiden and his colleagues introduce Juicer, an open-source tool used in three-dimensional (3-D) genome sequencing (Hi-C) processes.
Scientists cut “Gordian knot” in the human genome Jul 18, 2016 Emerging field of 3-D genome surgery sheds light on female development in mammals.
Baylor researchers advance rat model to enhance understanding of Rett syndrome Jul 15, 2016 Researchers at Baylor College of Medicine have developed a novel rat model to better understand what causes patients with RTT to lose behavioral, cognitive and physical abilities.
Primate brain development can help explain human developmental disorders Jul 13, 2016 Baylor scientists helped associate observed changes in gene expression during development with significant human disease characteristics.
Collisions during DNA replication and transcription contribute to mutagenesis Jun 29, 2016 Researchers have determined that Collisions during DNA replication and transcription can significantly contribute to mutagenesis.
Baylor College of Medicine welcomes Dr. Chonghui Cheng Jun 24, 2016 Dr. Chonghui Cheng joins Baylor's Lester and Sue Smith Breast Center and the Department of Molecular and Human Genetics as an associate professor, continuing her work to explore how RNA regulation controls breast cancer metastasis.
Negative feedback loops help maintain function of mutated proteins Jun 22, 2016 A study by Cullen Chair and Professor Olivier Lichtarge and Dr. Christophe Herman pins down a process by which some mutations may foster an organism’s long term adaptation while putting its immediate fitness at less risk.